AVAMYS NASAL SPRAY 10 GM

How AVAMYS NASAL SPRAY 10 GM Works

• AVAMYS Nasal Spray 10 GM contains fluticasone furoate, a synthetic corticosteroid, as its active ingredient. It is primarily used to manage symptoms of allergic rhinitis, including nasal congestion, runny nose, itching, and sneezing. Fluticasone furoate works by reducing inflammation in the nasal passages. When you spray Avamys into your nose, the fluticasone furoate is deposited onto the nasal lining.
• Fluticasone furoate acts as a potent anti-inflammatory agent. It binds to glucocorticoid receptors in the nasal mucosa. This binding initiates a cascade of intracellular events that ultimately lead to the suppression of inflammatory processes. Specifically, it inhibits the release of inflammatory mediators such as histamine, cytokines, and leukotrienes. These mediators are responsible for triggering the symptoms of allergic rhinitis.
• By reducing the release of these inflammatory substances, fluticasone furoate effectively diminishes the swelling and irritation in the nasal passages. This leads to a decrease in nasal congestion, making it easier to breathe through your nose. Additionally, it reduces the production of mucus, alleviating a runny nose. The itching and sneezing associated with allergic rhinitis are also lessened as the inflammatory response is subdued.
• Unlike some other nasal sprays, Avamys is designed to have minimal systemic absorption. This means that very little of the drug is absorbed into the bloodstream. This reduces the risk of systemic side effects, making it a safer option for long-term use in many patients. However, it is still important to use the spray as directed by your doctor to minimize any potential risks.
• The full effect of Avamys may not be noticeable immediately. It typically takes a few days of regular use to achieve maximum benefit. It's crucial to continue using the spray as prescribed, even if your symptoms improve, to maintain control over your allergic rhinitis. Consistent use helps to keep the inflammation at bay and prevent the recurrence of symptoms.
• In summary, AVAMYS Nasal Spray works by delivering fluticasone furoate directly to the nasal passages, where it reduces inflammation by inhibiting the release of inflammatory mediators. This action alleviates nasal congestion, runny nose, itching, and sneezing, providing relief from the symptoms of allergic rhinitis with minimal systemic absorption when used as directed.

Like all medicines, Avamys Nasal Spray can cause side effects, although not everybody gets them. **Very Common (may affect more than 1 in 10 people):** * Nosebleeds **Common (may affect up to 1 in 10 people):** * Nasal ulceration (sores inside the nose) - which may cause irritation or discomfort. * Headache **Uncommon (may affect up to 1 in 100 people):** * Nosebleeds **Rare (may affect up to 1 in 1,000 people):** * Hypersensitivity reactions: Skin rash, swelling, itching and urticaria (hives). **Very Rare (may affect up to 1 in 10,000 people):** * Anaphylaxis: Severe allergic reactions that may cause difficulty breathing. * Glaucoma * Cataracts * Increased ocular pressure * Nasal Septal Perforation

• If you forget to use Avamys Nasal Spray, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and use your next dose at the regular time. Do not use a double dose to make up for a missed dose.

• Keep AVAMYS NASAL SPRAY 10GM away from the reach of children and pets.
• Store AVAMYS NASAL SPRAY 10GM at room temperature.

• Shake Well Before Use: Always shake the AVAMYS nasal spray bottle gently before each use to ensure a consistent dose of the medication. This helps to evenly distribute the active ingredient, fluticasone furoate, in the spray.
• Prime the Spray: Before the first use, or if you haven't used the spray for a few days, prime the pump by spraying it into the air until a fine mist appears. This ensures that you get the correct dose.
• Proper Nasal Administration: Tilt your head slightly forward and insert the nozzle into one nostril, aiming towards the outer wall of your nose. This helps to avoid spraying directly onto the septum, which can cause irritation. Breathe in gently as you spray.
• Clean the Nozzle Regularly: After each use, clean the nozzle with a clean, dry tissue and replace the dust cap. This prevents the nozzle from becoming blocked and keeps the spray hygienic. Avoid using water to clean the nozzle.
• Consistent Usage is Key: Use AVAMYS nasal spray every day, as prescribed by your doctor, even if you feel better. It may take several days for the medication to reach its full effect. Consistent use will help manage your symptoms effectively.
• Store Properly: Store AVAMYS nasal spray in an upright position at room temperature, away from direct sunlight and heat. Keep out of reach of children.
• Consult Your Doctor: If your symptoms do not improve after using AVAMYS nasal spray for a week, or if they worsen, consult your doctor. They may need to adjust your treatment plan.

• AVAMYS NASAL SPRAY 10 GM is generally not affected by food. It can be used regardless of meals. There are no known food interactions with this medication.