CALCIUM FOLINATE 15MG/2ML INJECTION
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CALCIUM FOLINATE 15MG/2ML INJECTION
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CALCIUM FOLINATE 15MG/2ML INJECTION

By FRESENIUS KABI INDIA PVT LTD

MRP

146

₹63.75

56.34 % OFF


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Product DetailsArrow

About CALCIUM FOLINATE 15MG/2ML INJECTION

  • CALCIUM FOLINATE 15MG/2ML INJECTION is an anticancer drug belonging to the class of detoxifying agents, containing the active ingredient Calcium Folinate. It plays a crucial role in managing megaloblastic anemia, a condition characterized by the presence of large, immature, and dysfunctional red blood cells (megaloblasts) in the bone marrow. Furthermore, it is strategically employed to enhance the effectiveness of 5-fluorouracil, a chemotherapy drug, in the treatment of certain cancers. CALCIUM FOLINATE 15MG/2ML INJECTION boosts the drug's efficacy while simultaneously mitigating its potential toxicity.
  • Beyond its role in cancer treatment and anemia management, this medication is also valuable in addressing overdosages of folic acid antagonists, a class of drugs that interfere with folic acid metabolism. Additionally, CALCIUM FOLINATE 15MG/2ML INJECTION exhibits a protective effect on healthy cells, shielding them from the harmful effects of certain chemotherapy drugs through a mechanism known as "rescue." This "rescue" action minimizes collateral damage during chemotherapy, improving patient outcomes and quality of life. It's important to note that CALCIUM FOLINATE 15MG/2ML INJECTION can be a vital part of cancer treatment plans by protecting healthy cells and reducing side effects.
  • This drug is contraindicated in patients with known hypersensitivity reactions to Calcium Folinate or any of the other ingredients in the formulation. It is crucial to inform your doctor about any previous allergic reactions you have experienced. This medicine may trigger allergic reactions in susceptible individuals, manifesting as itching, difficulty breathing, swelling of the face or throat, and a rapid heartbeat. Seek immediate medical attention if you develop any of these symptoms.
  • Excessive doses of CALCIUM FOLINATE 15MG/2ML INJECTION should be avoided, as they may compromise the antitumor activity of methotrexate, particularly in the context of central nervous system (CNS) tumors where this drug tends to accumulate after repeated administrations. Careful monitoring and dosage adjustments are essential to maintain the therapeutic balance.
  • Currently, there is no evidence to suggest that folic acid, and by extension, CALCIUM FOLINATE 15MG/2ML INJECTION, induces harmful effects when administered during pregnancy. However, it remains uncertain whether this injection can cause fetal harm. Consequently, CALCIUM FOLINATE 15MG/2ML INJECTION should only be used during pregnancy if deemed clearly necessary by a healthcare professional, carefully weighing the potential benefits against the possible risks to the fetus.
  • During pregnancy, methotrexate should only be administered under strict indications, where the benefits of the drug to the mother are carefully weighed against potential hazards to the fetus. It is also unknown whether this medicine is excreted in human breast milk. Therefore, the use of CALCIUM FOLINATE 15MG/2ML INJECTION during breastfeeding should be determined based on therapeutic indications and a careful assessment of the potential risks and benefits. Inform your physician about all medications, herbal remedies, and supplements you are currently taking before initiating treatment with CALCIUM FOLINATE 15MG/2ML INJECTION.

Uses of CALCIUM FOLINATE 15MG/2ML INJECTION

  • Treatment of Megaloblastic Anemia: CALCIUM FOLINATE 15MG/2ML INJECTION is crucial in managing megaloblastic anemia, a condition characterized by abnormally large red blood cells. It helps in the production of normal red blood cells by providing the necessary folate.
  • Reduce the Toxicity of Methotrexate: CALCIUM FOLINATE 15MG/2ML INJECTION is administered to lessen the harmful effects of methotrexate, a medication used in chemotherapy and to treat certain autoimmune diseases. It acts as a rescue medication, helping to protect healthy cells from methotrexate's toxic effects.
  • Overdose of Folic Acid Antagonists: CALCIUM FOLINATE 15MG/2ML INJECTION is utilized to counteract the effects of an overdose of folic acid antagonists. By supplying an active form of folate, it helps to overcome the blockade caused by these drugs.
  • Enhance the Effectiveness of 5-Fluorouracil: CALCIUM FOLINATE 15MG/2ML INJECTION can be combined with 5-fluorouracil in cancer treatment to boost the latter's effectiveness. It enhances the cytotoxic effect on cancer cells, leading to improved treatment outcomes.

Side Effects of CALCIUM FOLINATE 15MG/2ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. CALCIUM FOLINATE 15MG/2ML INJECTION can cause serious side effects like reduced blood cell counts, inflammation in the mouth and intestine lining, and severe allergic reactions. Common side effects include nausea, vomiting, severe diarrhea, and redness and swelling of the palms of hands and soles of feet.

  • Reduced number of blood cells
  • Inflammation in the lining of mouth and intestine
  • Severe allergic reactions
  • Nausea, vomiting, severe diarrhoea
  • Redness and swelling of palms of hands and soles of feet

Safety Advice for CALCIUM FOLINATE 15MG/2ML INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

It is not known whether CALCIUM FOLINATE 15MG/2ML INJECTION can cause foetal harm, when administered to pregnant women. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Dosage of CALCIUM FOLINATE 15MG/2ML INJECTIONArrow

  • CALCIUM FOLINATE 15MG/2ML INJECTION will be administered to you by a trained healthcare professional in a hospital or clinical setting. This ensures the injection is given safely and effectively.
  • The medicine can be given slowly into a vein, either as a direct injection or as a longer infusion, allowing for controlled absorption. Alternatively, it may be injected directly into a muscle, depending on your specific medical needs and the doctor's judgment.
  • It is crucial that you do not attempt to self-administer this medication. The correct dosage and administration technique are vital for its effectiveness and to minimize potential side effects. A healthcare professional is best equipped to handle this.
  • Your doctor will determine the precise dose of CALCIUM FOLINATE 15MG/2ML INJECTION based on several factors, including the specific disease or condition being treated, its severity, your overall health, weight, kidney function, and response to treatment. Regular monitoring will help the doctor adjust the dosage as needed.

How to store CALCIUM FOLINATE 15MG/2ML INJECTION?Arrow

  • Keep CALCIUM FOLINATE 15MG INJ 2ML away from the reach of children and pets.
  • Store CALCIUM FOLINATE 15MG INJ 2ML at room temperature.

Benefits of CALCIUM FOLINATE 15MG/2ML INJECTIONArrow

  • CALCIUM FOLINATE 15MG/2ML INJECTION, also known as folinic acid, is crucial for DNA production and red blood cell formation. It plays a vital role when cells divide rapidly, such as in cancer cells and normal bone marrow cells, where folic acid is essential for cell division. This medication boosts the effects of folic acid in the body by being absorbed by cells through a specific transporter protein. Once inside the cells, it converts into the active form of folic acid, enabling the cells to produce DNA and form new cells.
  • This drug is administered following methotrexate treatment to protect normal cells that rely on folate for growth. Methotrexate can interfere with folic acid metabolism, harming both cancer cells and healthy cells. CALCIUM FOLINATE 15MG/2ML INJECTION acts as a rescue medication by providing a readily usable form of folate to the healthy cells, minimizing the toxic effects of methotrexate. By supplementing the body with this active form of folate, CALCIUM FOLINATE 15MG/2ML INJECTION helps restore the normal function of these cells and supports their recovery after exposure to methotrexate.
  • Furthermore, CALCIUM FOLINATE 15MG/2ML INJECTION ensures that essential bodily functions that depend on folate, such as cell growth, division, and the creation of genetic material, are maintained even when methotrexate is present. This targeted approach helps to mitigate the harmful side effects of chemotherapy while allowing the chemotherapy to effectively target and destroy cancer cells. This support is critical for patients undergoing cancer treatment, as it helps to improve their overall well-being and ability to tolerate the therapy.

How to use CALCIUM FOLINATE 15MG/2ML INJECTIONArrow

  • CALCIUM FOLINATE 15MG/2ML INJECTION will be administered by a trained healthcare professional in a hospital or clinical setting. It is not intended for self-administration. This medication will be given slowly, either directly into a vein (intravenously) as an injection or infusion, or alternatively, it can be injected into a muscle (intramuscularly).
  • The specific method and rate of administration will be determined by your doctor based on your individual needs and the treatment protocol for your condition. The dosage of CALCIUM FOLINATE 15MG/2ML INJECTION will be carefully calculated by your doctor, taking into account the severity of your condition, your overall health, and any other medications you may be taking. It is crucial to adhere to the prescribed dosage and schedule for optimal results.
  • Your doctor will monitor you closely during and after the injection to assess your response to the medication and manage any potential side effects. If you have any concerns or questions about the administration of CALCIUM FOLINATE 15MG/2ML INJECTION, please do not hesitate to discuss them with your healthcare provider.

FAQs

What are the special precautions I should be aware of before starting treatment with CALCIUM FOLINATE 15MG/2ML INJECTION?Arrow

This drug is eliminated from the body primarily through the kidneys. Patients with impaired kidney function may need a lower dose or less frequent dosing of CALCIUM FOLINATE 15MG/2ML INJECTION.

Can CALCIUM FOLINATE 15MG/2ML INJECTION be used in combination with other drugs?Arrow

Yes, CALCIUM FOLINATE 15MG/2ML INJECTION is used as an antidote to reduce the toxic effects of methotrexate, a chemotherapy drug that is used to treat certain types of cancer.

What does CALCIUM FOLINATE 15MG/2ML INJECTION do to your body?Arrow

CALCIUM FOLINATE 15MG/2ML INJECTION works by supplying the body with the necessary folate, which is required for the production of red blood cells, DNA synthesis, and other important cellular functions.

When you must not be given CALCIUM FOLINATE 15MG/2ML INJECTION?Arrow

CALCIUM FOLINATE 15MG/2ML INJECTION should not be given to patients who have had an allergic reaction to it or any of its components.

What is CALCIUM FOLINATE 15MG/2ML INJECTION rescue?Arrow

CALCIUM FOLINATE 15MG/2ML INJECTION rescue is typically used in cancer treatment, particularly in the treatment of leukaemia and lymphoma. This involves administering CALCIUM FOLINATE 15MG/2ML INJECTION to patients who are receiving high-dose methotrexate treatment. CALCIUM FOLINATE 15MG/2ML INJECTION helps to reduce the toxic effects of methotrexate on healthy cells by providing a form of folic acid that can be used by the body to make new cells and DNA.

Can I drive after receiving a CALCIUM FOLINATE 15MG/2ML INJECTION?Arrow

It is generally safe to drive after receiving a CALCIUM FOLINATE 15MG/2ML INJECTION. However, you may experience dizziness or drowsiness as a side effect, which may impair your ability to operate a vehicle or heavy machinery. It is important to wait until you feel fully alert and able to function normally before driving.

NULL interaction of CALCIUM FOLINATE 15MG/2ML INJECTION with other drungsArrow

No specific known interaction information is available with this medicine.

Special care is needed if you are elderly and you are about to receive any fluorouracil treatment and CALCIUM FOLINATE 15MG/2ML injection at the same time in case you undergo radiotherapy or stomach trouble. Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.Arrow

This information should be provided to your doctor so that they can adjust your treatment plan accordingly.

What is CALCIUM FOLINATE?Arrow

CALCIUM FOLINATE is a molecule/combination used for making CALCIUM FOLINATE 15MG/2ML INJECTION.

For which ailments/diseases/conditions is CALCIUM FOLINATE 15MG/2ML INJECTION prescribed?Arrow

CALCIUM FOLINATE 15MG/2ML INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

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Hospira UK Ltd, Electronic Medicines Compendium (EMC)

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Pfizer Singapore

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Package leaflet: Summary of the product characteristics for the user. www.hpra.ie.

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Calcium folinate sandoz - medsafe. Available at:

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CALCIUM FOLINATE 15MG/2ML INJECTION

CALCIUM FOLINATE 15MG/2ML INJECTION

MRP

146

₹63.75

56.34 % OFF

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