CALCIUM FOLINATE 50MG/5ML INJECTION
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CALCIUM FOLINATE 50MG/5ML INJECTION
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CALCIUM FOLINATE 50MG/5ML INJECTION

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CALCIUM FOLINATE 50MG/5ML INJECTION

By FRESENIUS KABI INDIA PVT LTD

MRP

400

₹198

50.5 % OFF

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Product DetailsArrow

About CALCIUM FOLINATE 50MG/5ML INJECTION

  • CALCIUM FOLINATE 50MG/5ML INJECTION is an important medication classified as a detoxifying agent, with Calcium Folinate as its active ingredient. It plays a vital role in treating megaloblastic anemia, a condition characterized by the presence of abnormally large and dysfunctional red blood cells in the bone marrow. Beyond anemia, this injection is also used alongside 5-fluorouracil in cancer treatment. It boosts the effectiveness of 5-fluorouracil, enhancing its ability to target cancer cells while simultaneously reducing its toxic side effects on the body.
  • Furthermore, CALCIUM FOLINATE 50MG/5ML INJECTION serves as an antidote in cases of folic acid antagonist overdose. These antagonists can interfere with the body's use of folic acid, leading to complications. This injection helps to reverse these effects and restore normal folic acid function. Another critical function of this medication is its ability to protect healthy cells from the harmful effects of chemotherapy. It acts as a rescue agent, minimizing the damage caused by chemotherapy drugs and supporting the body's recovery during cancer treatment.
  • However, it is crucial to remember that CALCIUM FOLINATE 50MG/5ML INJECTION is not suitable for everyone. Individuals with known hypersensitivity reactions to Calcium Folinate or any of the injection's components should not use it. Allergic reactions can manifest as itching, breathing difficulties, facial or throat swelling, and a rapid heartbeat. If any of these symptoms arise, immediate medical attention is essential. It's also important to avoid excessive doses of this medication, as they can potentially reduce the effectiveness of methotrexate, especially in cases of CNS tumors where the drug tends to accumulate after repeated treatments. Always follow your doctor's prescribed dosage carefully.
  • If you are pregnant or breastfeeding, discuss the use of CALCIUM FOLINATE 50MG/5ML INJECTION with your healthcare provider. While there is no clear evidence that folic acid causes harm during pregnancy, the potential risks and benefits should be carefully weighed. Methotrexate, in particular, should only be used during pregnancy when absolutely necessary, considering the possible risks to the fetus. It is also unknown whether this medicine passes into breast milk, so caution is advised during breastfeeding. Before starting CALCIUM FOLINATE 50MG/5ML INJECTION, inform your doctor about all other medications you are taking, including herbal remedies and supplements, to avoid potential interactions.

Uses of CALCIUM FOLINATE 50MG/5ML INJECTION

  • Treatment of Megaloblastic Anemia: CALCIUM FOLINATE 50MG/5ML INJECTION is crucial in managing megaloblastic anemia, a condition characterized by abnormally large red blood cells due to folate deficiency. It helps restore normal red blood cell production.
  • Reduce the Toxicity of Methotrexate: CALCIUM FOLINATE 50MG/5ML INJECTION is used to counteract the toxic effects of methotrexate, a medication used in cancer treatment and for certain autoimmune diseases. It helps protect healthy cells from methotrexate's harmful effects.
  • Overdose of Folic Acid Antagonists: CALCIUM FOLINATE 50MG/5ML INJECTION is administered in cases of overdose with folic acid antagonists, such as trimethoprim or pyrimethamine. It reverses the effects of these drugs by providing an active form of folate.
  • Enhance the Effectiveness of 5-Fluorouracil: CALCIUM FOLINATE 50MG/5ML INJECTION can be used in conjunction with 5-fluorouracil in cancer chemotherapy. It enhances the cytotoxic effect of 5-fluorouracil on cancer cells, improving treatment outcomes.

Side Effects of CALCIUM FOLINATE 50MG/5ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. CALCIUM FOLINATE 50MG/5ML INJECTION can cause side effects.

  • Reduced number of blood cells
  • Inflammation in the lining of mouth and intestine
  • Severe allergic reactions
  • Nausea, vomiting, severe diarrhoea
  • Redness and swelling of palms of hands and soles of feet

Safety Advice for CALCIUM FOLINATE 50MG/5ML INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

It is not known whether CALCIUM FOLINATE 50MG/5ML INJECTION can cause foetal harm, when administered to pregnant women. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Dosage of CALCIUM FOLINATE 50MG/5ML INJECTIONArrow

  • CALCIUM FOLINATE 50MG/5ML INJECTION will be administered by a qualified healthcare professional within a hospital or clinical setting. This ensures proper monitoring and management of any potential side effects.
  • The method of administration will be determined by your doctor. It can be given slowly into a vein, either as a direct injection or a longer infusion, or alternatively, it may be injected directly into a muscle.
  • It is crucial that you do not attempt to self-administer CALCIUM FOLINATE 50MG/5ML INJECTION. This medication requires careful handling and precise administration techniques that only trained professionals can provide.
  • The specific dosage of CALCIUM FOLINATE 50MG/5ML INJECTION will be determined by your doctor. They will consider several factors, including the specific condition being treated, its severity, your overall health, and your response to the medication. Regular monitoring will help optimize the dosage for the best possible outcome.
  • Your doctor may also adjust the dosage based on the results of blood tests and other relevant investigations. It is important to attend all scheduled appointments and inform your doctor about any other medications you are taking, as these may influence the dosage of CALCIUM FOLINATE 50MG/5ML INJECTION.

How to store CALCIUM FOLINATE 50MG/5ML INJECTION?Arrow

  • Keep CALCIUM FOLINATE 50MG INJ 5ML away from the reach of children and pets.
  • Store CALCIUM FOLINATE 50MG INJ 5ML at room temperature.

Benefits of CALCIUM FOLINATE 50MG/5ML INJECTIONArrow

  • CALCIUM FOLINATE 50MG/5ML INJECTION, also known as folinic acid, plays a crucial role in DNA production and the formation of red blood cells. It's particularly important when cells are rapidly dividing, such as in cancer cells or the bone marrow's normal cells, where folic acid is essential for cell division.
  • This medication amplifies the effects of folic acid within the body. Cells absorb it via a specific transporter protein, converting it into folic acid's active form. This active form is then utilized by the cells to create DNA and generate new cells. Think of it as a boost to the cell's ability to replicate and function properly.
  • CALCIUM FOLINATE 50MG/5ML INJECTION is frequently administered following methotrexate treatment. Methotrexate, while effective against certain conditions, can also inhibit folate metabolism. This injection acts as a 'rescue' agent, helping to restore folate levels in normal cells that depend on it for growth and survival, mitigating the adverse effects of methotrexate. It allows normal cells to recover and continue functioning effectively. It is a valuable tool in managing treatment side effects and ensuring patient well-being.
  • It is important to remember that CALCIUM FOLINATE 50MG/5ML INJECTION is prescribed to help protect the normal cells in your body from the harmful effects of some medications. Always follow your doctor's instructions carefully.

How to use CALCIUM FOLINATE 50MG/5ML INJECTIONArrow

  • CALCIUM FOLINATE 50MG/5ML INJECTION will be administered to you by a qualified healthcare professional in a hospital or clinical setting. It is crucial to understand that this medication is not intended for self-administration.
  • The method of administration will be determined by your doctor and may involve a slow injection directly into a vein (intravenous injection or infusion) or an injection into a muscle (intramuscular injection). The healthcare provider will carefully monitor you during the administration process.
  • The precise dosage of CALCIUM FOLINATE 50MG/5ML INJECTION will be determined by your doctor, taking into account several factors, including the specific disease or condition being treated, your overall health status, and any other medications you may be taking. It is essential to adhere to the prescribed dosage and schedule for optimal results.
  • If you have any questions or concerns regarding the administration of CALCIUM FOLINATE 50MG/5ML INJECTION, please do not hesitate to discuss them with your doctor or healthcare provider. They can provide you with detailed information and address any anxieties you may have.

FAQs

What are the special precautions I should be aware of before starting treatment with CALCIUM FOLINATE 50MG/5ML INJECTION?Arrow

This drug is eliminated from the body primarily through the kidneys. Patients with impaired kidney function may need a lower dose or less frequent dosing of CALCIUM FOLINATE 50MG/5ML INJECTION.

Can CALCIUM FOLINATE 50MG/5ML INJECTION be used in combination with other drugs?Arrow

Yes, CALCIUM FOLINATE 50MG/5ML INJECTION is used as an antidote to reduce the toxic effects of methotrexate, a chemotherapy drug that is used to treat certain types of cancer.

What does CALCIUM FOLINATE 50MG/5ML INJECTION do to your body?Arrow

CALCIUM FOLINATE 50MG/5ML INJECTION works by supplying the body with the necessary folate, which is required for the production of red blood cells, DNA synthesis, and other important cellular functions.

When you must not be given CALCIUM FOLINATE 50MG/5ML INJECTION?Arrow

CALCIUM FOLINATE 50MG/5ML INJECTION should not be given to patients who have had an allergic reaction to it or any of its components.

What is CALCIUM FOLINATE 50MG/5ML INJECTION rescue?Arrow

CALCIUM FOLINATE 50MG/5ML INJECTION rescue is typically used in cancer treatment, particularly in the treatment of leukaemia and lymphoma. This involves administering CALCIUM FOLINATE 50MG/5ML INJECTION to patients who are receiving high-dose methotrexate treatment. CALCIUM FOLINATE 50MG/5ML INJECTION helps to reduce the toxic effects of methotrexate on healthy cells by providing a form of folic acid that can be used by the body to make new cells and DNA.

Can I drive after receiving a CALCIUM FOLINATE 50MG/5ML INJECTION?Arrow

It is generally safe to drive after receiving a CALCIUM FOLINATE 50MG/5ML INJECTION. However, you may experience dizziness or drowsiness as a side effect, which may impair your ability to operate a vehicle or heavy machinery. It is important to wait until you feel fully alert and able to function normally before driving.

NULL interaction of CALCIUM FOLINATE 50MG/5ML INJECTION with other drungsArrow

For more information about this medicine, please consult your doctor.

Special care is needed if you are elderly and you are about to receive any fluorouracil treatment and CALCIUM FOLINATE 50MG/5ML injection at the same time in case you undergo radiotherapy or stomach trouble. Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.Arrow

It is important to tell your doctor about all of your medications, so they can check for potential interactions.

What is CALCIUM FOLINATE?Arrow

CALCIUM FOLINATE is molecule/combination used for making CALCIUM FOLINATE 50MG/5ML INJECTION.

What is the use of CALCIUM FOLINATE 50MG/5ML INJECTION in Oncology?Arrow

CALCIUM FOLINATE 50MG/5ML INJECTION is used in Oncology for the treatment of cancer.

References

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Hospira UK Ltd, Electronic Medicines Compendium (EMC)

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Pfizer Singapore

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Package leaflet: Summary of the product characteristics for the user. www.hpra.ie.

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Calcium folinate sandoz - medsafe. Available at:

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CALCIUM FOLINATE 50MG/5ML INJECTION

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50.5 % OFF

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