CCBEST M 10/25MG TABLET 10'S

How CCBEST M 10/25MG TABLET 10'S Works

• CCBEST M 10/25MG TABLET 10'S is a combination medication designed to manage hypertension (high blood pressure) effectively. It combines two active ingredients, Cilnidipine and Metoprolol, each working through different mechanisms to lower blood pressure and reduce the risk of cardiovascular complications.
• Cilnidipine, a calcium channel blocker, primarily targets L-type calcium channels found in the smooth muscle cells of blood vessels. These channels play a crucial role in regulating vascular tone. When calcium ions enter these cells, they cause the muscles to contract, leading to vasoconstriction (narrowing of blood vessels) and increased blood pressure. Cilnidipine selectively blocks these calcium channels, preventing calcium influx. This results in the relaxation of smooth muscle cells, causing vasodilation (widening of blood vessels). By widening the blood vessels, Cilnidipine reduces peripheral vascular resistance, the force against which the heart must pump, ultimately lowering blood pressure. Moreover, Cilnidipine's action extends to the renal afferent arterioles, which supply blood to the kidneys. By dilating these arterioles, Cilnidipine improves blood flow to the kidneys, which can be particularly beneficial for individuals with hypertension and kidney issues. Unlike some other calcium channel blockers, Cilnidipine exhibits a unique dual action by also blocking N-type calcium channels, which are present in nerve terminals. This additional action helps to reduce sympathetic nerve activity, further contributing to blood pressure reduction and providing a potential benefit in reducing heart rate.
• Metoprolol, a beta-blocker, primarily targets beta-1 adrenergic receptors found in the heart. These receptors are responsible for mediating the effects of adrenaline (epinephrine) and noradrenaline (norepinephrine), hormones that increase heart rate and blood pressure. Metoprolol selectively blocks these beta-1 receptors, diminishing the effects of adrenaline and noradrenaline on the heart. This results in several beneficial effects: Reduced Heart Rate: By blocking beta-1 receptors, Metoprolol slows down the heart rate, giving the heart more time to fill with blood between beats. Decreased Cardiac Output: Metoprolol reduces the force with which the heart contracts, leading to a decrease in the amount of blood pumped out of the heart per minute (cardiac output). Lowered Blood Pressure: Both the reduced heart rate and decreased cardiac output contribute to lowering blood pressure. Metoprolol also affects the renin-angiotensin-aldosterone system (RAAS), a hormonal system that regulates blood pressure and fluid balance. By blocking beta-1 receptors in the kidneys, Metoprolol reduces the release of renin, an enzyme that initiates the RAAS cascade. This further contributes to lowering blood pressure and reducing fluid retention.
• In summary, CCBEST M 10/25MG TABLET 10'S effectively lowers blood pressure through the complementary actions of Cilnidipine and Metoprolol. Cilnidipine widens blood vessels by blocking calcium channels and reducing sympathetic nerve activity, while Metoprolol slows down the heart rate and reduces cardiac output by blocking beta-1 receptors. This dual mechanism provides a comprehensive approach to managing hypertension and reducing the risk of cardiovascular events.
• It's crucial to remember that this medication should be taken as prescribed by a healthcare professional. They will determine the appropriate dosage and monitor your blood pressure regularly to ensure the medication is working effectively and safely. Always inform your doctor about any other medications you are taking, as well as any existing medical conditions, to avoid potential drug interactions or adverse effects.

Common side effects of CCBEST M 10/25MG TABLET may include: Headache, Dizziness, Nausea, Vomiting, Stomach upset, Diarrhea, Constipation, Fatigue, Weakness, Muscle cramps, Increased urination, Blurred vision, Dry mouth, Increased thirst, Skin rash, Itching, Swelling of ankles or feet. Uncommon side effects may include: Changes in heart rhythm, Low blood pressure, Fainting, Difficulty breathing, Allergic reactions, Liver problems, Kidney problems, Changes in blood sugar levels, Nervousness, Anxiety, Depression, Sleep disturbances, Hair loss, Sexual dysfunction.

• If you miss a dose of CCBEST M 10/25MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep CCBEST M 10/25MG TAB 1X10 away from the reach of children and pets.
• Store CCBEST M 10/25MG TAB 1X10 at room temperature.

• Take CCBEST M 10/25MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting them, even if you feel better. This helps ensure the medication works effectively and minimizes the risk of side effects or withdrawal symptoms. Consistent adherence to your doctor's instructions is crucial for managing your condition.
• CCBEST M 10/25MG TABLET 10'S can be taken with or without food, but try to take it at the same time each day to maintain a consistent level of medication in your body. This can help improve the effectiveness of the medication and reduce the likelihood of missed doses. Establishing a daily routine can make it easier to remember to take your tablet.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting CCBEST M 10/25MG TABLET 10'S. Certain medications can interact with CCBEST M, potentially altering its effectiveness or increasing the risk of side effects. Providing a complete list of your medications helps your doctor make informed decisions about your treatment plan.
• Be aware of potential side effects associated with CCBEST M 10/25MG TABLET 10'S, such as dizziness, lightheadedness, or changes in blood pressure. If you experience any bothersome or persistent side effects, contact your doctor promptly. They can provide guidance on managing side effects or adjust your treatment plan if necessary. Do not ignore or self-treat any adverse reactions.
• Store CCBEST M 10/25MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage helps maintain the integrity and effectiveness of the medication. Do not store the medicine in the bathroom due to high humidity. Always check the expiration date before taking the medicine.

• CCBEST M 10/25MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood levels. Avoid consuming large amounts of grapefruit juice while taking this medicine, as it may increase the blood levels of the drug.