COLIHENZ P 400MG TABLET 10'S

How COLIHENZ P 400MG TABLET 10'S Works

• COLIHENZ P 400MG TABLET 10'S is a combination medication containing two active ingredients: Aceclofenac and Paracetamol. These components work synergistically to alleviate pain and reduce inflammation. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that inhibits the production of prostaglandins, which are responsible for causing pain, inflammation, and fever. By blocking the cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, Aceclofenac reduces the synthesis of these inflammatory mediators.
• Paracetamol, also known as Acetaminophen, is an analgesic and antipyretic. While its exact mechanism of action is not fully understood, it is believed to work primarily in the central nervous system (CNS) to reduce pain and fever. Paracetamol elevates the pain threshold, meaning it reduces the perception of pain. It also inhibits the heat-regulating center in the brain, leading to a decrease in body temperature during fever.
• When taken together, Aceclofenac and Paracetamol provide comprehensive pain relief. Aceclofenac targets the inflammation at the site of injury or pain, while Paracetamol modulates pain perception in the brain. This combination is effective in managing various painful conditions, such as osteoarthritis, rheumatoid arthritis, muscle pain, toothache, and menstrual cramps. The synergistic effect of these two drugs allows for a lower dose of each individual component, potentially reducing the risk of side effects compared to taking each drug alone.
• In summary, COLIHENZ P 400MG TABLET 10'S works by Aceclofenac reducing inflammation and pain locally by blocking prostaglandin production, while Paracetamol reduces pain and fever centrally by affecting pain perception and heat regulation in the brain. This dual action provides effective relief from pain and inflammation.

Common side effects of Colihenz P 400mg Tablet may include nausea, vomiting, stomach pain, heartburn, loss of appetite, diarrhea, constipation, and drowsiness. Less common but potentially serious side effects include allergic reactions (rash, itching, swelling), liver problems (yellowing of skin/eyes, dark urine), kidney problems (changes in urine output), and gastrointestinal bleeding (bloody/black stools, persistent stomach pain). Other rare side effects may involve changes in blood counts or neurological symptoms. This is not an exhaustive list. Consult your doctor if you experience any unusual symptoms while taking this medication.

• If you miss a dose of COLIHENZ P 400MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep COLIHENZ P 400MG TAB 1X10 away from the reach of children and pets.
• Store COLIHENZ P 400MG TAB 1X10 at room temperature.

• **Take COLIHENZ P exactly as prescribed by your doctor:** Adhering to the prescribed dosage and schedule is crucial for optimal effectiveness and to minimize potential side effects. Do not alter the dosage or frequency without consulting your healthcare provider. Consistent use ensures a steady level of the medication in your system, maximizing its therapeutic benefits.
• **COLIHENZ P can be taken with or without food:** While you can take it either way, taking it with food may help reduce the chance of stomach upset. If you experience nausea or discomfort when taking it on an empty stomach, try taking it after a meal or with a snack. However, always follow your doctor's specific recommendations.
• **Inform your doctor about all other medications you're taking:** COLIHENZ P can interact with other drugs, potentially reducing its effectiveness or increasing the risk of adverse effects. Provide a complete list of all prescription medications, over-the-counter drugs, herbal supplements, and vitamins you're currently using. This information will help your doctor manage potential drug interactions safely.
• **Stay hydrated while taking COLIHENZ P:** Drinking plenty of water is essential to help flush out the medication and prevent kidney problems. Aim for at least 8 glasses of water a day, or as directed by your healthcare provider. Proper hydration supports kidney function and helps your body process the medication more efficiently.
• **Be aware of potential side effects:** Common side effects of COLIHENZ P may include nausea, vomiting, diarrhea, or abdominal pain. If these side effects persist or become severe, contact your doctor immediately. Other less common but serious side effects may occur, so it's important to be vigilant and report any unusual symptoms to your healthcare provider promptly. Do not drive or operate machinery if you feel dizzy or drowsy.

• While taking COLIHENZ P 400MG TABLET 10'S, there are no specific food restrictions. It can be taken with or without food. Consult your doctor for personalized advice.