COSVATE S OINTMENT 30 GM

How COSVATE S OINTMENT 30 GM Works

• COSVATE S OINTMENT 30 GM is a potent topical medication combining two active ingredients: Clobetasol Propionate and Salicylic Acid. This synergistic formulation is designed to treat inflammatory skin conditions characterized by excessive scaling or hyperkeratosis. Understanding how each component works is crucial to appreciating the ointment's overall efficacy.
• Clobetasol Propionate is a highly potent corticosteroid. It works by reducing inflammation, itching, and redness by suppressing the activity of the immune system in the skin. At the cellular level, clobetasol binds to glucocorticoid receptors within skin cells. This binding initiates a cascade of events that ultimately decrease the production of inflammatory mediators such as prostaglandins and leukotrienes. These mediators are responsible for the symptoms of inflammation. By inhibiting their production, clobetasol effectively reduces swelling, itching, and irritation. Furthermore, clobetasol narrows blood vessels in the affected area, further reducing redness and swelling. It essentially calms down the overactive immune response that is causing the skin problem.
• Salicylic Acid is a keratolytic agent, meaning it helps to soften and shed the outer layer of skin (stratum corneum). It works by increasing the amount of moisture in the skin and dissolving the substance that causes skin cells to stick together. This action promotes desquamation (shedding of skin cells), which helps to reduce scaling and allows clobetasol propionate to penetrate the skin more effectively. Salicylic acid also possesses mild anti-inflammatory and antimicrobial properties, which can further contribute to the overall therapeutic effect.
• The combination of clobetasol propionate and salicylic acid in COSVATE S OINTMENT 30 GM offers a dual-action approach. Salicylic acid prepares the skin by removing scales and dead skin cells, thereby enhancing the penetration and absorption of clobetasol propionate. This allows the corticosteroid to reach the affected area more effectively, maximizing its anti-inflammatory and immunosuppressive effects. The result is a reduction in inflammation, itching, and scaling, leading to improved skin condition.
• In essence, COSVATE S OINTMENT 30 GM works by reducing inflammation through the action of clobetasol propionate and promoting the shedding of dead skin cells through the action of salicylic acid. This combination provides a comprehensive approach to treating skin conditions characterized by both inflammation and excessive scaling.

Like all medicines, COSVATE S OINTMENT 30 GM can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Itching * Burning sensation * Local skin irritation * Dryness * Thinning of the skin * Changes in skin color * Acne * Increased hair growth **Uncommon Side Effects (may affect up to 1 in 100 people):** * Stretch marks * Spider veins * Skin rash * Allergic contact dermatitis **Rare Side Effects (may affect up to 1 in 1,000 people):** * Worsening of infection * Suppression of adrenal gland function **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Glaucoma * Cataracts **Other potential side effects:** * **Skin:** Folliculitis (inflammation of hair follicles), secondary infection. * **Endocrine:** Hyperglycemia (high blood sugar), glycosuria (sugar in the urine), Cushing's syndrome (symptoms include weight gain, moon face, and high blood pressure). **If you experience any of these side effects, especially if they are severe or persistent, stop using COSVATE S OINTMENT 30 GM and consult your doctor or pharmacist immediately.**

• If you forget to apply Cosvate S Ointment, apply it as soon as you remember. However, if it is almost time for your next application, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.

• Keep COSVATE S OINTMENT 30GM away from the reach of children and pets.
• Store COSVATE S OINTMENT 30GM at room temperature.

• Apply a thin layer: Only apply a small amount of Cosvate S Ointment to the affected area. A thin layer is sufficient for effective treatment and minimizes the risk of side effects. Over application won't speed up healing and can actually worsen skin irritation.
• Use as directed: Follow your doctor's instructions regarding frequency and duration of use. Do not use Cosvate S Ointment for longer than prescribed. Prolonged use can lead to adverse effects, including skin thinning and increased susceptibility to infections.
• Avoid contact with eyes and mouth: Be careful to avoid getting the ointment in your eyes, mouth, or other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Consult a doctor if irritation persists.
• Not for open wounds: Do not apply Cosvate S Ointment on open wounds, cuts, or severely irritated skin. It is intended for use on specific skin conditions as diagnosed by a healthcare professional. Applying it to open wounds can delay healing and increase the risk of infection.
• Monitor for side effects: Watch for any signs of skin irritation, burning, itching, or allergic reactions. If you experience any unusual symptoms, discontinue use and consult your doctor immediately. Promptly addressing side effects can prevent them from becoming more severe.

• COSVATE S OINTMENT 30 GM is for external use only and is unlikely to interact with food. However, avoid applying the ointment near the mouth to prevent accidental ingestion.