ES-LC 50MG/5ML INJECTION
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ES-LC 50MG/5ML INJECTION
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ES-LC 50MG/5ML INJECTION

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ES-LC 50MG/5ML INJECTION

By ESPERER BIORESEARCH

MRP

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325

₹64

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Product DetailsArrow

About ES-LC 50MG/5ML INJECTION

  • ES-LC 50MG/5ML INJECTION contains leucovorin calcium, a substance related to folic acid, a vital vitamin. It belongs to the class of medications known as folic acid analogs. This medication is primarily used to mitigate the harmful effects of methotrexate, a drug used in the treatment of specific cancers. It serves as a protective agent, reducing the severity of methotrexate's side effects.
  • Furthermore, ES-LC 50MG/5ML INJECTION is crucial in treating cases of methotrexate overdose, whether accidental or intentional. It is also effective against overdoses of drugs belonging to a similar class as methotrexate. Its applications extend to colorectal cancer treatment, where it is used in conjunction with other anticancer drugs to target cancer originating in the colon or rectum. In some instances, it is also employed to address anemia resulting from folic acid deficiency.
  • It is important to avoid using ES-LC 50MG/5ML INJECTION if you have a known allergy to leucovorin calcium, calcium folinate, or any of the other components of the injection. Individuals with specific types of anemia, such as pernicious anemia or megaloblastic anemia associated with vitamin B12 deficiency, should also refrain from using this medication. Prior to starting treatment, inform your doctor about any pre-existing conditions, including anemia, kidney problems, heart issues, or liver ailments. Disclose all medications you are currently taking, especially those used to control seizures. Immediately notify your healthcare provider if you experience symptoms such as wheezing, difficulty breathing, skin rashes, itching, hives, or swelling of the lips, face, or tongue.

Uses of ES-LC 50MG/5ML INJECTION

  • Methotrexate overdose and toxicity: Information on managing the risks associated with methotrexate overdose and toxicity.
  • Prevent the harmful effects of methotrexate or similar medications: Ways to prevent the negative effects of medications like ES-LC 50MG/5ML INJECTION.
  • Colorectal cancer: Information about colorectal cancer.
  • Anemia: Information about anemia, a condition in which the body doesn't have enough healthy red blood cells.

Side Effects of ES-LC 50MG/5ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. Common side effects include diarrhea, nausea, vomiting, inflamed and sore mouth, and tiredness. Serious side effects may include allergic reactions.

  • Diarrhea
  • Nausea
  • Vomiting
  • Inflamed and sore mouth
  • Tiredness
  • Allergic reactions

Safety Advice for ES-LC 50MG/5ML INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

There is a limited number of studies on the safety of ES-LC 50MG/5ML INJECTION during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Dosage of ES-LC 50MG/5ML INJECTIONArrow

  • ES-LC 50MG/5ML INJECTION will be administered to you by a qualified healthcare professional, such as a physician or a registered nurse who is specifically trained in the administration of cancer chemotherapy drugs. This ensures that the injection is given safely and effectively.
  • The specific dosage of ES-LC 50MG/5ML INJECTION, as well as the duration of your treatment, will be carefully determined by your doctor. This decision will be based on a comprehensive assessment of your individual disease condition, the severity of your cancer, and other relevant factors, such as your overall health and any other medications you may be taking.
  • ES-LC 50MG/5ML INJECTION is administered either intravenously, meaning directly into your vein, or intramuscularly, meaning directly into your muscle. The method of administration will depend on your specific disease condition and the doctor's best judgment for optimal treatment.
  • During the administration of ES-LC 50MG/5ML INJECTION, you will be closely monitored for any potential side effects or adverse reactions. It is important to inform your healthcare provider immediately if you experience any unusual symptoms or discomfort during or after the injection. Regular blood tests and other monitoring procedures may be conducted to assess your response to the treatment and to ensure your safety and well-being throughout the course of therapy.

How to store ES-LC 50MG/5ML INJECTION?Arrow

  • Keep ES-LC 50MG INJ 5ML away from the reach of children and pets.
  • Store ES-LC 50MG INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of ES-LC 50MG/5ML INJECTIONArrow

  • ES-LC 50MG/5ML INJECTION works by interfering with certain enzymes in the body, specifically dihydrofolate reductase. This enzyme is crucial for the activation of folic acid, a vital nutrient involved in cell growth and division. By inhibiting this enzyme, ES-LC 50MG/5ML INJECTION can counteract the effects of medications like methotrexate, which are used to treat conditions like cancer and autoimmune diseases. Methotrexate works by blocking folic acid metabolism, and ES-LC 50MG/5ML INJECTION can help to reduce its toxic effects.
  • In cases of anemia caused by folic acid deficiency, ES-LC 50MG/5ML INJECTION provides the body with the necessary folic acid to produce healthy red blood cells. Red blood cells are essential for carrying oxygen throughout the body, and a deficiency can lead to fatigue, weakness, and other health problems. By supplementing with folic acid, ES-LC 50MG/5ML INJECTION helps to restore normal red blood cell production and alleviate the symptoms of anemia.
  • Furthermore, ES-LC 50MG/5ML INJECTION can be used in conjunction with other cancer medications, such as 5-fluorouracil, to enhance their therapeutic effects. 5-fluorouracil is an anticancer drug that works by interfering with DNA synthesis in cancer cells. ES-LC 50MG/5ML INJECTION can help to increase the effectiveness of 5-fluorouracil by making cancer cells more sensitive to its effects, leading to improved treatment outcomes. This combination therapy is often used in the treatment of colorectal cancer and other types of cancer.
  • It's important to note that ES-LC 50MG/5ML INJECTION should only be used under the guidance and supervision of a qualified healthcare professional. The dosage and duration of treatment will depend on the individual's specific medical condition and response to therapy. Regular monitoring may be necessary to ensure that the medication is working effectively and to minimize the risk of side effects.

How to use ES-LC 50MG/5ML INJECTIONArrow

  • ES-LC 50MG/5ML INJECTION will be administered to you by a trained healthcare professional, such as a physician or nurse, who specializes in cancer chemotherapy. The dosage and duration of your treatment will be carefully determined by your doctor, taking into account several crucial factors. These include the specific type and stage of your cancer, the severity of your condition, your overall health status, and your response to the medication. Regular monitoring and adjustments to the treatment plan may be necessary to optimize its effectiveness and minimize potential side effects.
  • The method of administration will also depend on your individual needs and the characteristics of your cancer. ES-LC 50MG/5ML INJECTION is typically administered either intravenously (directly into a vein) or intramuscularly (directly into a muscle). Intravenous administration allows the medication to enter your bloodstream quickly and circulate throughout your body. Intramuscular administration involves injecting the medication into a muscle, where it is gradually absorbed into the bloodstream. Your doctor will choose the most appropriate method of administration based on your specific circumstances.
  • It's important to follow your doctor's instructions carefully and attend all scheduled appointments for your ES-LC 50MG/5ML INJECTION treatment. If you have any questions or concerns about the medication, its administration, or potential side effects, don't hesitate to discuss them with your healthcare team. They are there to provide you with the information and support you need throughout your cancer treatment journey.

FAQs

Why is ES-LC 50MG/5ML INJECTION given 24 hours after methotrexate?Arrow

ES-LC 50MG/5ML INJECTION is usually administered 24 hours after methotrexate so that it does not interfere with the therapeutic effect of methotrexate. It can also be used in methotrexate overdose; it should be administered as soon as possible.

Can ES-LC 50MG/5ML INJECTION cause swelling?Arrow

ES-LC 50MG/5ML INJECTION may cause allergic reactions like rash, low blood pressure, wheezing, shortness of breath, and swelling of the face or throat.

Can ES-LC 50MG/5ML INJECTION cause seizures?Arrow

There is no evidence that ES-LC 50MG/5ML INJECTION cause seizures. But the medicine can affect the effect of seizure medication when administered concurrently. Inform your physician about all your medicines, including over-the-counter medications.

How long does it take for ES-LC 50MG/5ML INJECTION to work?Arrow

ES-LC 50MG/5ML INJECTION starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

What measures should be taken to ensure the prompt excretion of methotrexate during treatment with ES-LC 50MG/5ML INJECTION?Arrow

A healthcare professional will monitor you during the treatment with this medicine. Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor the alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

NULL interaction of ES-LC 50MG/5ML INJECTION with other drungsArrow

There are no known interactions of ES-LC 50MG/5ML INJECTION with other drugs.

What is the advice related to ES-LC 50MG/5ML INJECTION?Arrow

If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much ES-LC 50MG/5ML Injection. contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine. 

What molecule/combination is used for making ES-LC 50MG/5ML INJECTION?Arrow

LEUCOVORIN CALCIUM is molecule/combination used for making ES-LC 50MG/5ML INJECTION.

For what type of ailments/diseases/conditions is ES-LC 50MG/5ML INJECTION prescribed?Arrow

ES-LC 50MG/5ML INJECTION is prescribed for Oncology related ailments/diseases/conditions.

References

Book Icon

Calcium Folinate 10 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. 2020

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HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet].

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Best and cheapest medicine.

Shubham Jain

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Reviewed on 23-11-2022

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Nisha Khan

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Reviewed on 01-07-2023

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Reviewed on 27-11-2023

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Reviewed on 13-04-2024

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(5/5)

Excellent service

Ali Akhtar

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Reviewed on 26-07-2023

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(5/5)

Marketer / Manufacturer Details

ESPERER BIORESEARCH

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India

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ES-LC 50MG/5ML INJECTION

ES-LC 50MG/5ML INJECTION

MRP

₹

325

₹64

80.31 % OFF

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અસ્વીકરણ

અહીંની કન્ટેન્ટ માત્ર માહિતીના હેતુઓ માટે છે અને વ્યાવસાયિક તબીબી સલાહ, નિદાન અથવા સારવારનો વિકલ્પ બનવાનો હેતુ નથી. તબીબી સ્થિતિને લગતા કોઈપણ પ્રશ્નો માટે કૃપા કરીને ચિકિત્સક અથવા અન્ય યોગ્ય આરોગ્ય પ્રદાતાની સલાહ લો. કોઈપણ માહિતી અને અનુગામી ક્રિયા અથવા નિષ્ક્રિયતા પર મેડકાર્ટ ફક્ત વપરાશકર્તાના જોખમ પર છે, અને અમે તેના માટે કોઈ જવાબદારી લેતા નથી. પ્લેટફોર્મ પરનો કન્ટેન્ટ વ્યાવસાયિક અને યોગ્ય તબીબી સલાહના વિકલ્પ તરીકે ધ્યાનમાં લેવી જોઈએ નહીં અથવા તેનો ઉપયોગ કરવો જોઈએ નહીં.દવાઓ, પરીક્ષણો અને/અથવા રોગોને લગતી કોઈપણ પ્રશ્ન માટે કૃપા કરીને તમારા ડૉક્ટરની સલાહ લો, કારણ કે અમે સમર્થન આપીએ છીએ, અને ડૉક્ટર-દર્દી સંબંધને બદલશો નહીં.

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