HUMSTARD 30/70 VIAL 10 ML

How HUMSTARD 30/70 VIAL 10 ML Works

• HUMSTARD 30/70 VIAL 10 ML is a premixed human insulin formulation containing 30% soluble insulin and 70% isophane insulin. This combination provides both rapid-acting and intermediate-acting insulin effects, helping to control blood sugar levels throughout the day.
• The soluble insulin component (30%) is a rapid-acting insulin that starts working within 30 minutes of injection. It helps to cover the rise in blood sugar levels that occur after meals. This rapid onset helps manage postprandial hyperglycemia, preventing spikes in blood glucose following food consumption.
• The isophane insulin component (70%) is an intermediate-acting insulin. It has a slower onset and a longer duration of action, providing a basal level of insulin throughout the day and night. This helps to control blood sugar levels between meals and during sleep, contributing to overall glycemic control.
• When injected subcutaneously, HUMSTARD 30/70 is absorbed into the bloodstream. The soluble insulin is quickly absorbed, initiating the lowering of blood glucose. The isophane insulin is absorbed more slowly, creating a prolonged effect that extends blood sugar control over a longer period.
• Insulin works by allowing glucose to enter cells, where it can be used for energy. In people with diabetes, the body either doesn't produce enough insulin or can't effectively use the insulin it produces. HUMSTARD 30/70 helps to compensate for this deficiency by providing exogenous insulin.
• Specifically, insulin binds to insulin receptors on cell membranes, triggering a cascade of intracellular events. This leads to the translocation of glucose transporters (GLUT4) to the cell surface, facilitating glucose uptake into cells of muscle, liver, and adipose tissue. The glucose is then either used for immediate energy, stored as glycogen in the liver and muscles, or converted to fat for long-term energy storage.
• By promoting glucose uptake into cells, insulin lowers blood glucose levels. It also inhibits the liver from producing more glucose and prevents the breakdown of glycogen and fat. This comprehensive action helps maintain blood glucose levels within a target range, reducing the risk of hyperglycemia (high blood sugar) and its associated complications.
• The premixed nature of HUMSTARD 30/70 offers convenience for patients who require both rapid and intermediate-acting insulin. It simplifies the injection process by providing a single injection that covers both mealtime and basal insulin needs. However, it's crucial to follow a consistent meal schedule and carbohydrate intake to optimize the effectiveness of this premixed insulin.
• Consistent use of HUMSTARD 30/70, along with diet and exercise, helps manage blood sugar effectively. Regular monitoring of blood glucose levels is necessary to adjust the dosage of HUMSTARD 30/70 and ensure optimal glycemic control. This allows for personalized diabetes management, tailoring the treatment to individual needs and lifestyle.

Like all medicines, Humulin NPH may cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Hypoglycemia (low blood sugar). Early symptoms include: sweating, dizziness, tremor, hunger, headache, fast heartbeat. * Local allergic reactions: Redness, swelling, or itching at the injection site. **Uncommon side effects (may affect up to 1 in 100 people):** * Lipodystrophy: Changes in the fat tissue at the injection site (pitting or thickening of the skin). * Systemic allergy: Generalized itching, difficulty breathing, wheezing, fast heartbeat, drop in blood pressure. **Rare side effects (may affect up to 1 in 1,000 people):** * None reported in clinical trials, but theoretically possible. **Very rare side effects (may affect up to 1 in 10,000 people):** * None reported. **Other possible side effects:** * Weight gain * Edema (swelling), especially in ankles and feet **If you experience any of the following, seek immediate medical attention:** * Severe allergic reaction (anaphylaxis) * Severe hypoglycemia (very low blood sugar) leading to unconsciousness or seizures.

• If you miss a dose of Huminsulin 30/70, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Contact your doctor for advice if you are concerned about managing your blood sugar levels.

• Keep HUMSTARD 30/70 VIAL 10ML away from the reach of children and pets.
• Store HUMSTARD 30/70 VIAL 10ML in a refrigerator (2 - 8°C). Do not freeze.

• **Understand Your Insulin:** HUMSTARD 30/70 is a premixed insulin, containing 30% short-acting and 70% intermediate-acting insulin. This means it covers your insulin needs at meal times and between meals. Always double-check the vial before each use to ensure it is the correct type and concentration.
• **Proper Storage is Key:** Store unopened vials of HUMSTARD 30/70 in the refrigerator (2°C to 8°C). Do not freeze. Once in use, the vial can be kept at room temperature (below 25°C) for up to 28 days, away from direct heat and sunlight. Discard the vial after 28 days, even if it still contains insulin.
• **Injection Technique Matters:** Inject HUMSTARD 30/70 subcutaneously (under the skin) as instructed by your doctor or diabetes educator. Rotate injection sites within the same area (e.g., abdomen, thigh, or upper arm) to prevent lipodystrophy (lumps or pits in the skin). Use a new needle for each injection to ensure sterility and reduce discomfort.
• **Timing is Crucial:** Administer HUMSTARD 30/70 approximately 30 minutes before a meal. This allows the short-acting insulin component to start working when you begin eating. Consistent timing helps maintain stable blood sugar levels.
• **Monitor Your Blood Sugar Regularly:** Regularly monitor your blood glucose levels as advised by your healthcare provider. This will help you understand how HUMSTARD 30/70 is working for you and whether any adjustments to your dosage or diet are needed. Keep a log of your blood sugar readings to share with your doctor at your appointments.
• **Be Prepared for Hypoglycemia:** Know the signs and symptoms of hypoglycemia (low blood sugar), such as sweating, shakiness, dizziness, and confusion. Always carry a fast-acting source of glucose (e.g., glucose tablets, juice, or hard candy) with you to treat hypoglycemia promptly. Inform your family and friends about how to recognize and treat hypoglycemia in case you are unable to do so yourself.
• **Never Share Your Insulin:** HUMSTARD 30/70 is prescribed specifically for you. Sharing your insulin with others can be dangerous and lead to serious health consequences.
• **Consult Your Doctor Regularly:** Schedule regular check-ups with your doctor or diabetes educator to review your insulin regimen, blood sugar control, and overall health. They can provide personalized guidance and make any necessary adjustments to your treatment plan.

• HUMSTARD 30/70 VIAL 10 ML should be administered 15 minutes before or after meals. Consistent timing with meals is crucial for maintaining stable blood sugar levels. Avoid drastic changes in diet without consulting your doctor, as this can affect your insulin needs. Be mindful of the carbohydrate content of your meals, as insulin dosage is often adjusted based on carbohydrate intake.