INSUGEN 30/70 100IU VIAL 10 ML

How INSUGEN 30/70 100IU VIAL 10 ML Works

• INSUGEN 30/70 100IU VIAL 10 ML is a premixed insulin formulation containing 30% rapid-acting insulin and 70% intermediate-acting insulin. This combination is designed to provide both a quick burst of insulin to cover mealtime glucose spikes and a sustained release to manage blood sugar levels between meals and overnight. The rapid-acting component, typically a soluble insulin, starts working within 30 minutes of injection, helping to control the rise in blood glucose that occurs after eating. This is crucial for preventing hyperglycemia immediately following meals.
• The intermediate-acting component, usually an isophane insulin (NPH), has a slower onset of action and a longer duration. It begins to work within 1-3 hours and can last for up to 24 hours. This provides a basal level of insulin, helping to keep blood glucose levels stable throughout the day and night. By combining these two types of insulin, INSUGEN 30/70 mimics the natural insulin release pattern of a healthy pancreas, which releases a bolus of insulin after meals and a steady background level throughout the day.
• Insulin works by allowing glucose to enter cells, where it can be used for energy. In people with diabetes, the pancreas either doesn't produce enough insulin (Type 1 diabetes) or the body's cells become resistant to insulin (Type 2 diabetes). INSUGEN 30/70 supplements the body's own insulin supply, enabling glucose to be transported from the bloodstream into cells. This helps to lower blood glucose levels and prevent the complications of diabetes, such as nerve damage, kidney damage, and eye damage.
• When injected subcutaneously, insulin binds to insulin receptors on the surface of cells, triggering a cascade of intracellular events. This leads to the translocation of glucose transporters (GLUT4) to the cell membrane, which facilitates the uptake of glucose into the cell. The liver also plays a crucial role in glucose homeostasis. Insulin promotes glucose storage in the liver in the form of glycogen and inhibits the production of glucose by the liver. This coordinated action of insulin in various tissues helps to maintain stable blood glucose levels.
• The 30/70 ratio in INSUGEN 30/70 is designed to provide a balance between mealtime and basal insulin coverage. This ratio may need to be adjusted based on individual needs, dietary habits, and activity levels. Regular monitoring of blood glucose levels is essential to determine the optimal dosage and timing of INSUGEN 30/70 injections. Factors such as stress, illness, and changes in diet or exercise can affect insulin requirements, so it's important to work closely with a healthcare provider to manage diabetes effectively.

- Hypoglycemia (low blood sugar): This is the most common side effect. Symptoms can include shakiness, sweating, rapid heartbeat, blurred vision, dizziness, and confusion. - Injection site reactions: Redness, swelling, itching, or pain at the injection site. - Lipodystrophy: Changes in fat tissue at the injection site (either thickening or thinning of the skin). - Allergic reactions: These can range from mild skin reactions to severe, life-threatening reactions (anaphylaxis). Symptoms of a severe allergic reaction include rash, itching, swelling of the face, tongue, or throat, trouble breathing, and dizziness. - Weight gain: Insulin can promote weight gain. - Edema: Swelling of the ankles and feet. - Visual disturbances: Temporary blurred vision may occur when starting insulin therapy. - Peripheral neuropathy: Nerve damage causing pain, numbness, and tingling in the hands and feet (long-term complication). - Insulin resistance: The body's cells become less responsive to insulin over time.

• If you miss a dose of INSUGEN 30/70, it is important to monitor your blood sugar levels regularly.
• Take your next dose as soon as you remember, but only if it is at least 2 hours before your next meal. If it is closer to your next mealtime, skip the missed dose and take your next scheduled dose as usual.
• Do not take a double dose to make up for a missed one, as this can lead to hypoglycemia (low blood sugar).
• If you are unsure about what to do, consult your doctor or diabetes educator for guidance.

• Keep INSUGEN 30/70 100IU VIAL 10ML away from the reach of children and pets.
• Store INSUGEN 30/70 100IU VIAL 10ML in a refrigerator (2 - 8°C). Do not freeze.

• **Understand Your Insulin Type:** INSUGEN 30/70 is a premixed insulin containing 30% rapid-acting and 70% intermediate-acting insulin. This combination helps manage blood sugar levels after meals and between meals. Ensure you understand the proportions and how they affect your blood sugar.
• **Proper Storage is Key:** Store unopened INSUGEN 30/70 vials in the refrigerator (2°C to 8°C). Do not freeze. Once opened, the vial can be stored at room temperature (below 30°C) for up to 28 days. Discard the vial if it has been open for longer, even if there is insulin remaining.
• **Administer Subcutaneously:** INSUGEN 30/70 is administered via subcutaneous injection (under the skin). Rotate injection sites (abdomen, thigh, upper arm) to prevent lipodystrophy (skin thickening or pitting) which can affect insulin absorption. Use a new needle for each injection to maintain sterility and minimize discomfort.
• **Timing Matters:** Inject INSUGEN 30/70 approximately 30 minutes before a meal. This allows the rapid-acting component to start working when you eat. Consult your doctor or diabetes educator for personalized timing based on your meal schedule and blood sugar levels.
• **Monitor Blood Sugar Regularly:** Regular blood glucose monitoring is crucial while using INSUGEN 30/70. This helps you understand how the insulin is working and allows you to adjust your diet and activity levels accordingly. Keep a record of your blood sugar readings to share with your healthcare provider.
• **Watch for Hypoglycemia:** Be aware of the signs and symptoms of hypoglycemia (low blood sugar), such as sweating, shakiness, dizziness, confusion, and hunger. Carry a source of fast-acting glucose (glucose tablets, juice, or candy) with you at all times. Treat hypoglycemia immediately and inform your doctor about any frequent or severe episodes.
• **Carry Identification:** Always carry identification indicating that you have diabetes and are using insulin. This is important in case of an emergency. Consider wearing a medical alert bracelet or necklace.
• **Travel Smart with Insulin:** When traveling, keep your insulin in its original packaging and carry it in a cooler bag with ice packs. Do not store insulin in checked luggage, as temperature fluctuations can affect its potency. Inform airport security that you are carrying insulin and syringes.
• **Diet and Exercise are Essential:** Insulin is most effective when combined with a healthy diet and regular exercise. Work with a registered dietitian to develop a meal plan that fits your needs and consult your doctor before starting a new exercise program.
• **Consult Your Healthcare Provider Regularly:** Regular check-ups with your doctor and diabetes educator are essential for managing your diabetes and ensuring that your insulin regimen is appropriate. Discuss any concerns or questions you have about your insulin therapy.

• It is important to have regular meals and monitor your blood glucose levels regularly while using INSUGEN 30/70 100IU VIAL 10 ML.
• The timing of your insulin dose should be coordinated with your food intake. Discuss any changes to your diet or meal schedule with your doctor.
• Be cautious about alcohol consumption, as it can affect blood sugar levels. Consume in moderation and monitor your blood glucose carefully.