KEFCLAV 200MG TABLET 4'S

How KEFCLAV 200MG TABLET 4'S Works

• KEFCLAV 200MG TABLET 4'S is a powerful combination antibiotic medication designed to combat a wide range of bacterial infections. It contains two active ingredients: cefixime and clavulanic acid. Cefixime is a cephalosporin antibiotic, while clavulanic acid is a beta-lactamase inhibitor. Understanding how each component works is crucial to appreciating the overall effectiveness of KEFCLAV 200MG TABLET 4'S.
• Cefixime works by interfering with the bacteria's ability to build cell walls. Bacteria, like all cells, need a protective outer layer. This layer, known as the cell wall, is crucial for their survival and replication. Cefixime specifically targets the enzymes responsible for synthesizing peptidoglycans, which are essential building blocks of the bacterial cell wall. By blocking these enzymes, cefixime prevents the bacteria from properly constructing their cell walls. This leads to weakened cell walls, making the bacteria vulnerable and eventually causing them to rupture and die. Because human cells do not have cell walls, cefixime selectively targets bacteria without harming the host's cells. The bactericidal action of cefixime makes it highly effective against various bacterial strains.
• However, some bacteria have developed a defense mechanism against cephalosporin antibiotics like cefixime. They produce enzymes called beta-lactamases, which can break down the structure of cefixime, rendering it ineffective. This is where clavulanic acid plays a critical role. Clavulanic acid is a beta-lactamase inhibitor. It works by binding to and inactivating the beta-lactamase enzymes produced by resistant bacteria. By inhibiting these enzymes, clavulanic acid prevents the breakdown of cefixime, allowing cefixime to reach its target and effectively inhibit bacterial cell wall synthesis. The presence of clavulanic acid restores the effectiveness of cefixime against bacteria that would otherwise be resistant.
• Therefore, the combination of cefixime and clavulanic acid in KEFCLAV 200MG TABLET 4'S provides a two-pronged approach to fighting bacterial infections. Cefixime directly attacks the bacterial cell wall, while clavulanic acid protects cefixime from being deactivated by bacterial enzymes. This synergistic effect broadens the spectrum of activity of KEFCLAV 200MG TABLET 4'S, making it effective against a wider range of bacteria, including those that have developed resistance to cefixime alone. This makes KEFCLAV 200MG TABLET 4'S a valuable tool in treating various infections, such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, and other bacterial ailments.
• In summary, KEFCLAV 200MG TABLET 4'S works by a dual mechanism: cefixime inhibits bacterial cell wall synthesis, leading to bacterial death, while clavulanic acid inhibits beta-lactamase enzymes, preventing the breakdown of cefixime. This combination enhances the antibiotic's efficacy and broadens its spectrum of activity, enabling it to combat a wider array of bacterial infections effectively. Always take KEFCLAV 200MG TABLET 4'S as prescribed by your healthcare provider to ensure optimal treatment and minimize the risk of antibiotic resistance.

Like all medicines, KEFCLAV 200MG TABLET 4'S can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Diarrhea * Nausea * Vomiting * Skin rash * Urticaria * Thrush (a fungal infection of the vagina, mouth or skin folds) **Uncommon Side Effects (may affect up to 1 in 100 people):** * Indigestion * Dizziness * Headache * Increase in some substances (enzymes) produced by the liver * Abdominal pain **Rare Side Effects (may affect up to 1 in 1,000 people):** * Skin rash, which may blister, and looks like small targets (central dark spots surrounded by a paler area, with a dark ring around the edge – erythema multiforme) * Low number of white blood cells (leukopenia) * Low number of platelets (cells that help the blood to clot) (thrombocytopenia) **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Allergic reactions (which can be severe, such as angioedema, anaphylaxis) * Drug-induced fever * Serum sickness-like syndrome * Hepatitis (inflammation of the liver) * Cholestatic jaundice (a liver problem causing yellowing of the skin or whites of the eyes) * Increased blood urea * Increased serum creatinine * Prolongation of bleeding time * Prolonged prothrombin time * Black tongue **Other Side Effects:** * Clostridium difficile colitis * Serious skin reactions: a widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome), and a more severe form causing extensive peeling of the skin (more than 30% of the body surface – toxic epidermal necrolysis) * Aseptic meningitis * Seizures (convulsions)

• If you miss a dose of KEFCLAV 200MG TABLET 4'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to catch up.

• Keep KEFCLAV 200MG TAB 1X4 away from the reach of children and pets.
• Store KEFCLAV 200MG TAB 1X4 at room temperature.

• Take KEFCLAV 200MG TABLET 4'S exactly as prescribed by your doctor. Do not adjust the dosage or frequency without consulting them, even if you start feeling better. Completing the full course of antibiotics is crucial to eliminate the infection and prevent antibiotic resistance. In most cases, you should take the medicine at regular intervals for better absorption.
• To minimize stomach upset, take KEFCLAV 200MG TABLET 4'S with food. The presence of food helps to reduce gastrointestinal side effects like nausea, vomiting, or diarrhea. If you experience persistent stomach problems, inform your doctor. Also ensure you store the medicine in a cool, dry place.
• If you have a known allergy to penicillin or cephalosporin antibiotics, inform your doctor before starting KEFCLAV 200MG TABLET 4'S. Allergic reactions can range from mild skin rashes to severe anaphylaxis. Seek immediate medical attention if you experience symptoms like hives, swelling, difficulty breathing, or wheezing. Your doctor may suggest an alternative if you are allergic.
• Maintain consistent timing when taking KEFCLAV 200MG TABLET 4'S. For instance, if you take it twice a day, space the doses approximately 12 hours apart. This helps maintain a steady level of the medication in your body, maximizing its effectiveness against the bacterial infection. Use an alarm if you need help remembering.
• Be aware of potential drug interactions. Inform your doctor about all other medications, supplements, and herbal products you are currently taking. KEFCLAV 200MG TABLET 4'S can interact with certain drugs, affecting their efficacy or increasing the risk of side effects. For example, it can affect oral contraceptives.

• KEFCLAV 200MG TABLET 4'S can be taken with or without food. However, it is generally recommended to take it with food to minimize potential stomach upset. If you experience nausea or stomach discomfort, taking it with a meal or snack might help.
• Avoid consuming large amounts of acidic foods or beverages (such as citrus fruits or juices, tomatoes, or vinegar-based dressings) at the same time as taking KEFCLAV 200MG TABLET 4'S, as this could potentially affect absorption.