LIPIROSE F 5MG TABLET 10'S

How LIPIROSE F 5MG TABLET 10'S Works

• LIPIROSE F 5MG TABLET 10'S is a combination medication containing two active ingredients: Rosuvastatin and Fenofibrate. Each component works through different mechanisms to manage cholesterol and triglyceride levels in the body, ultimately reducing the risk of cardiovascular diseases. Rosuvastatin belongs to a class of drugs called statins, while Fenofibrate is a fibrate.
• Rosuvastatin primarily functions by inhibiting an enzyme called HMG-CoA reductase. This enzyme is crucial in the liver's production of cholesterol. By blocking HMG-CoA reductase, rosuvastatin reduces the amount of cholesterol the liver produces. This leads to a decrease in LDL-cholesterol (bad cholesterol) levels in the bloodstream. Furthermore, rosuvastatin increases the number of LDL receptors on liver cells. These receptors bind to LDL-cholesterol in the blood, facilitating its removal from the bloodstream and further lowering LDL-cholesterol levels. Rosuvastatin also modestly increases HDL-cholesterol (good cholesterol) and lowers triglycerides.
• Fenofibrate works primarily by activating a protein called peroxisome proliferator-activated receptor alpha (PPARα). PPARα is found in various tissues, including the liver, heart, and muscles. When activated, PPARα increases the production of lipoprotein lipase (LPL), an enzyme that breaks down triglycerides in the blood. This leads to a significant reduction in triglyceride levels. Additionally, fenofibrate reduces the production of apolipoprotein C-III, an inhibitor of LPL, further enhancing triglyceride clearance. Fenofibrate also increases HDL-cholesterol levels, which helps to remove cholesterol from the arteries.
• The combined action of Rosuvastatin and Fenofibrate in LIPIROSE F 5MG TABLET 10'S provides a comprehensive approach to managing dyslipidemia (abnormal lipid levels). Rosuvastatin effectively lowers LDL-cholesterol, while Fenofibrate significantly reduces triglycerides and increases HDL-cholesterol. This combination is particularly beneficial for individuals with mixed dyslipidemia, characterized by elevated LDL-cholesterol, elevated triglycerides, and low HDL-cholesterol. By addressing all these lipid abnormalities, LIPIROSE F 5MG TABLET 10'S helps to reduce the risk of atherosclerosis (plaque buildup in the arteries), heart attack, stroke, and other cardiovascular complications. It's crucial to use this medication in conjunction with a healthy diet and regular exercise for optimal results, and always under the guidance of a healthcare professional.
• In summary, LIPIROSE F 5MG TABLET 10'S employs a dual-action mechanism. Rosuvastatin inhibits cholesterol production in the liver and increases LDL-cholesterol removal from the blood. Fenofibrate activates PPARα, which boosts triglyceride breakdown and increases HDL-cholesterol levels. Together, they provide a more comprehensive lipid management strategy than either drug could achieve alone, leading to better cardiovascular health outcomes when combined with lifestyle modifications.

Like all medicines, LIPIROSE F 5MG TABLET 10'S can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Headache * Muscle pain * Feeling sick (nausea) * Diarrhea * Indigestion * Changes in liver function blood tests * Increased blood sugar levels (hyperglycemia) **Uncommon side effects (may affect up to 1 in 100 people):** * Muscle weakness * Tiredness * Sleeplessness (insomnia) * Memory loss * Tingling or numbness in the fingers and toes (peripheral neuropathy) * Vomiting * Stomach pain * Constipation * Gas (flatulence) * Rash * Itching * Hair loss * Dizziness * Changes in taste * Blurred vision * Ringing in the ears (tinnitus) * Pancreatitis (inflammation of the pancreas) * Hives **Rare side effects (may affect up to 1 in 1,000 people):** * Severe muscle damage (rhabdomyolysis) * Liver problems (hepatitis) * Jaundice (yellowing of the skin and eyes) * Allergic reaction **Very rare side effects (may affect up to 1 in 10,000 people):** * Anaphylaxis (severe allergic reaction) * Liver failure **Other possible side effects:** * Erectile dysfunction * Depression * Breathing problems, including persistent cough and/or shortness of breath or fever * Joint pain

• If you miss a dose of LIPIROSE F 5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

• Keep LIPIROSE F 5MG TAB 1X10 away from the reach of children and pets.
• Store LIPIROSE F 5MG TAB 1X10 at room temperature.

• **Take LIPIROSE F 5MG TABLET 10'S as prescribed by your doctor:** Always follow your doctor's instructions regarding dosage and timing. Do not exceed the recommended dose or stop taking the medication without consulting your healthcare provider, even if you feel better. Consistency is key for optimal results.
• **Maintain a healthy lifestyle:** LIPIROSE F 5MG TABLET 10'S works best when combined with a heart-healthy diet, regular exercise, and weight management. Focus on reducing saturated and trans fats, increasing fiber intake, and engaging in at least 30 minutes of moderate-intensity exercise most days of the week. Quitting smoking and managing stress are also beneficial.
• **Be aware of potential side effects:** Like all medications, LIPIROSE F 5MG TABLET 10'S can cause side effects. Common side effects may include muscle pain, tenderness, or weakness, especially if accompanied by fever or fatigue. Other possible side effects include digestive issues, headache, and elevated liver enzymes. Contact your doctor immediately if you experience severe or persistent side effects.
• **Monitor your cholesterol levels regularly:** Your doctor will likely monitor your cholesterol levels periodically while you are taking LIPIROSE F 5MG TABLET 10'S. This helps assess the effectiveness of the medication and make any necessary adjustments to your treatment plan. Attend all scheduled follow-up appointments and discuss any concerns you have with your doctor.
• **Inform your doctor about other medications and medical conditions:** Before starting LIPIROSE F 5MG TABLET 10'S, inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Also, disclose any existing medical conditions, such as liver or kidney disease, diabetes, or thyroid problems. This information helps your doctor ensure the medication is safe and appropriate for you.

• LIPIROSE F 5MG TABLET 10'S can be taken with or without food. However, it is important to maintain a consistent dietary pattern.
• Avoid consuming large quantities of grapefruit or grapefruit juice while taking this medication, as it can increase the levels of rosuvastatin in your blood, potentially leading to increased side effects.
• Limit your intake of saturated and trans fats, cholesterol, and simple carbohydrates to enhance the effectiveness of the medication and improve your overall health.
• Consult your doctor or a registered dietitian for personalized dietary advice tailored to your specific health needs and conditions.