NADOXIN PLUS CREAM 10 GM

How NADOXIN PLUS CREAM 10 GM Works

• NADOXIN PLUS CREAM 10 GM is a combination medication formulated to combat various skin infections and inflammatory conditions. It leverages the synergistic effects of its active ingredients to provide comprehensive relief. The primary components work in concert to target the underlying causes of the infection and alleviate associated symptoms such as redness, swelling, and itching.
• Nadifloxacin, a fluoroquinolone antibiotic, plays a crucial role in eliminating bacterial infections. It functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, and repair. By blocking these enzymes, Nadifloxacin effectively prevents bacteria from multiplying and spreading, thereby controlling the infection.
• Ivermectin, an antiparasitic agent, targets parasitic infections of the skin. It works by binding to glutamate-gated chloride ion channels in invertebrate nerve and muscle cells. This binding leads to an increase in the permeability of the cell membrane to chloride ions, resulting in hyperpolarization of the nerve or muscle cell. Consequently, the parasite is paralyzed and ultimately dies, resolving the parasitic infection.
• Clotrimazole, an antifungal medication, addresses fungal infections by disrupting the synthesis of ergosterol, a vital component of fungal cell membranes. Ergosterol is crucial for maintaining the integrity and function of the fungal cell membrane. By inhibiting its production, Clotrimazole weakens the cell membrane, causing leakage of cellular contents and ultimately leading to fungal cell death.
• Beclometasone, a corticosteroid, provides relief from inflammation and itching. It works by suppressing the release of inflammatory mediators such as prostaglandins and leukotrienes. Beclometasone binds to glucocorticoid receptors within cells, which then regulate the expression of genes involved in the inflammatory response. This action reduces redness, swelling, and itching associated with skin infections and inflammatory conditions.
• In summary, NADOXIN PLUS CREAM 10 GM works through a multi-pronged approach. Nadifloxacin eradicates bacterial infections, Ivermectin eliminates parasitic infections, Clotrimazole combats fungal infections, and Beclometasone reduces inflammation and itching. This combination ensures comprehensive treatment of mixed skin infections, providing effective relief and promoting healing.

NADOXIN PLUS CREAM 10 GM, like all medications, can cause side effects, although not everyone experiences them. Common side effects may include: * Application site reactions: Burning, stinging, itching, redness, dryness, or scaling at the application site. * Skin irritation: Mild irritation or a temporary worsening of the skin condition. Less common or rare side effects may include: * Allergic reactions: Rash, hives, swelling of the face, lips, or tongue, difficulty breathing. * Photosensitivity: Increased sensitivity to sunlight, leading to sunburn more easily. * Hypopigmentation: Lightening of the skin color in the treated area. * Folliculitis: Inflammation of hair follicles. * Acneiform eruptions: Acne-like breakouts. * Systemic absorption: Although rare with topical application, systemic absorption can lead to side effects similar to those of oral corticosteroids, such as adrenal suppression. It is important to contact your doctor immediately if you experience any severe side effects or signs of an allergic reaction. This is not an exhaustive list, and other side effects may occur. If you notice any unusual symptoms, consult your doctor or pharmacist.

• If you forget to apply NADOXIN PLUS CREAM 10 GM at the scheduled time, apply it as soon as you remember. However, if it is almost time for your next application, skip the missed one and continue with your regular application schedule. Do not double the application to make up for the missed dose.

• Keep NADOXIN PLUS CREAM 10GM away from the reach of children and pets.
• Store NADOXIN PLUS CREAM 10GM at room temperature.

• **Wash and Dry Thoroughly:** Before applying Nadoxin Plus Cream, gently wash the affected area with a mild cleanser and pat it completely dry. This ensures the medication can penetrate effectively and reduces the risk of trapping moisture.
• **Apply a Thin Layer:** Use a small amount of Nadoxin Plus Cream to cover the affected area. Applying too much won't make it work faster and can sometimes lead to increased irritation. A thin layer is all that's needed.
• **Consistent Application is Key:** For best results, apply Nadoxin Plus Cream as directed by your doctor, usually once or twice daily. Consistency is crucial for the medication to work effectively in treating the infection.
• **Avoid Occlusive Dressings:** Unless specifically instructed by your doctor, avoid covering the treated area with airtight bandages or dressings. This can increase absorption and potentially lead to unwanted side effects.
• **Monitor for Irritation:** While Nadoxin Plus Cream is generally well-tolerated, some individuals may experience mild irritation, redness, or itching. If irritation persists or worsens, discontinue use and consult your doctor. Also avoid using other topical medications at the same time unless advised by your doctor.

• NADOXIN PLUS CREAM 10 GM is for external use only and is unlikely to interact with food. However, to minimize potential interactions and ensure optimal absorption, it is advisable to apply the cream on clean, dry skin, preferably 30 minutes before or after meals.