NEBISTAR SA TABLET 15'S

How NEBISTAR SA TABLET 15'S Works

• NEBISTAR SA TABLET 15'S is a combination medication primarily used to manage hypertension (high blood pressure). It combines nebivolol and valsartan, each working through distinct mechanisms to lower blood pressure effectively.
• Nebivolol is a beta-blocker that selectively blocks beta-1 adrenergic receptors, mainly found in the heart. By blocking these receptors, nebivolol slows down the heart rate and reduces the force of heart muscle contraction. This decreased cardiac output lowers blood pressure. Additionally, nebivolol stimulates the production of nitric oxide (NO) in the blood vessels. Nitric oxide is a vasodilator, meaning it helps relax and widen the blood vessels. This vasodilation further contributes to reduced blood pressure and improved blood flow.
• Valsartan, on the other hand, is an angiotensin II receptor blocker (ARB). Angiotensin II is a hormone that causes blood vessels to constrict, increasing blood pressure. It also stimulates the release of aldosterone, which leads to sodium and water retention by the kidneys, further elevating blood pressure. Valsartan blocks the action of angiotensin II by binding to the angiotensin II receptors in blood vessels and the adrenal gland. This prevents vasoconstriction and reduces aldosterone secretion. As a result, blood vessels relax, and the kidneys excrete more sodium and water, lowering blood volume and blood pressure.
• The synergistic action of nebivolol and valsartan provides a comprehensive approach to blood pressure management. Nebivolol reduces cardiac output and increases vasodilation, while valsartan prevents vasoconstriction and reduces fluid retention. This combination effectively lowers blood pressure, reducing the risk of cardiovascular events such as heart attack, stroke, and kidney damage. Regular use of NEBISTAR SA TABLET 15'S, as prescribed by a healthcare professional, helps maintain healthy blood pressure levels and protects overall cardiovascular health. It is important to take the medication consistently and follow any lifestyle recommendations provided by your doctor, such as diet and exercise, to maximize its benefits.
• This medicine should be taken at the same time each day, preferably with or without food, as directed by your physician. Consistency is key to maintaining optimal blood pressure control.

Common side effects of Nebistar SA Tablet may include headache, dizziness, fatigue, and nausea. Some individuals might experience slow heartbeat, low blood pressure, shortness of breath, and swelling in the ankles or feet. Less common side effects can include diarrhea, constipation, vomiting, skin rash, itching, and visual disturbances. In rare cases, Nebistar SA Tablet can cause Raynaud's phenomenon (numbness and coldness in fingers and toes), worsening of psoriasis, and confusion or hallucinations. If you experience any severe or persistent side effects, it is crucial to consult your doctor.

• If you miss a dose of NEBISTAR SA TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep NEBISTAR SA TAB 1X15 away from the reach of children and pets.
• Store NEBISTAR SA TAB 1X15 at room temperature.

• **Take NEBISTAR SA TABLET 15'S exactly as prescribed by your doctor.** Do not change the dose or stop taking the medication without consulting them, as this could lead to serious heart problems. Usually it is recommended to take at same time each day to maintain consisten level of medicine in the body.
• **Monitor your blood pressure and heart rate regularly while taking NEBISTAR SA TABLET 15'S.** Keep a record of these measurements and share them with your doctor during follow-up appointments. This helps in dose adjustments and monitoring the effectiveness of the medication.
• **Inform your doctor about all other medications, supplements, or herbal products you are taking.** NEBISTAR SA TABLET 15'S can interact with other drugs, potentially affecting how they work or increasing the risk of side effects. Be especially cautious with cold remedies, NSAIDs (like ibuprofen), and certain antidepressants.
• **Be aware of potential side effects and what to do.** Common side effects include dizziness, fatigue, headache, and slow heart rate. If you experience any severe or persistent side effects, such as shortness of breath, chest pain, or swelling in your ankles/feet, seek immediate medical attention. Also, rise slowly from sitting or lying down to minimize dizziness.
• **Maintain a healthy lifestyle to support the effectiveness of NEBISTAR SA TABLET 15'S.** This includes following a balanced diet low in sodium and saturated fats, engaging in regular physical activity (as advised by your doctor), managing stress, and avoiding excessive alcohol consumption. Quitting smoking is also highly recommended for overall cardiovascular health.
• **If you have diabetes, monitor your blood sugar levels closely.** NEBISTAR SA TABLET 15'S may mask some of the symptoms of low blood sugar, making it harder to recognize. Consult your doctor for advice on managing your diabetes effectively while taking this medication.

• NEBISTAR SA TABLET 15'S may be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood levels. Avoid consuming large amounts of grapefruit juice while taking this medicine, as it may increase the blood levels of nebivolol.