NEXPRO L CAPSULE 10'S

How NEXPRO L CAPSULE 10'S Works

• NEXPRO L CAPSULE 10'S is a combination medication designed to treat gastrointestinal issues, primarily focusing on acid reflux and related symptoms. It contains two active ingredients: Esomeprazole and Levosulpiride. Each component addresses the problem through distinct mechanisms, offering a comprehensive approach to symptom relief and healing.
• Esomeprazole, a proton pump inhibitor (PPI), is the cornerstone of NEXPRO L's action against acid reflux. PPIs work by directly reducing the amount of acid produced in the stomach. Specialized cells in the stomach lining, known as parietal cells, are responsible for secreting hydrochloric acid, which aids in digestion. Esomeprazole selectively binds to and inhibits the hydrogen-potassium ATPase enzyme system (the 'proton pump') located on these parietal cells. By blocking this pump, Esomeprazole effectively suppresses the final step in acid production. This leads to a significant reduction in stomach acidity, alleviating symptoms such as heartburn, acid regurgitation, and difficulty swallowing. The reduced acidity also creates a more favorable environment for the healing of any existing esophageal damage caused by acid reflux, such as erosions or ulcers.
• Levosulpiride, the second active ingredient, is a prokinetic agent and a dopamine D2 receptor antagonist. It primarily works by influencing the motility (movement) of the gastrointestinal tract. Levosulpiride selectively blocks dopamine D2 receptors in the digestive system. Dopamine normally inhibits the release of acetylcholine, a neurotransmitter that stimulates muscle contractions in the gut. By blocking dopamine's action, Levosulpiride increases acetylcholine release. This, in turn, enhances the contractions of the esophageal and gastric muscles, promoting faster gastric emptying and reducing the likelihood of food and acid refluxing back into the esophagus. Furthermore, Levosulpiride helps to coordinate the movements of the digestive system, ensuring smoother and more efficient transit of food.
• The combined action of Esomeprazole and Levosulpiride in NEXPRO L CAPSULE 10'S addresses both the cause and the symptoms of acid reflux. Esomeprazole reduces acid production, while Levosulpiride improves gastric motility and reduces the chance of reflux. This dual-action approach provides effective relief from acid reflux symptoms, promotes healing of esophageal damage, and improves overall digestive function. It's important to note that while NEXPRO L can effectively manage acid reflux, it is typically prescribed for a specific duration, and long-term use should be monitored by a healthcare professional.

Common side effects of Nexpro L Capsule may include headache, nausea, vomiting, stomach pain, diarrhea, constipation, flatulence (gas), and dry mouth. Less common side effects can include skin rash, itching, dizziness, blurred vision, anxiety, depression, sleep disturbances, and changes in liver function tests. Rarely, it may cause serious allergic reactions, muscle pain or weakness, and blood disorders. Consult your doctor if you experience any persistent or severe side effects.

• If you miss a dose of NEXPRO L CAPSULE 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep NEXPRO L CAP 1X10 away from the reach of children and pets.
• Store NEXPRO L CAP 1X10 at room temperature.

• Take NEXPRO L Capsule 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. This ensures optimal effectiveness and minimizes the risk of side effects. Typically, it's taken once daily, preferably in the morning before a meal, for best absorption.
• If you miss a dose of NEXPRO L Capsule 10'S, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up, as this can increase the risk of adverse effects.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting NEXPRO L Capsule 10'S. This is crucial to avoid potential drug interactions that could reduce the effectiveness of the medication or increase the risk of side effects. Pay special attention to blood thinners, antifungals, and medications for HIV.
• NEXPRO L Capsule 10'S is generally well-tolerated, but some people may experience common side effects such as headache, diarrhea, stomach pain, flatulence, and nausea. If these side effects persist or become bothersome, consult your doctor. Seek immediate medical attention if you experience more serious side effects such as severe allergic reactions (rash, itching, swelling), signs of kidney problems (changes in urine output), or liver problems (yellowing of the skin or eyes).
• Lifestyle modifications can significantly improve the effectiveness of NEXPRO L Capsule 10'S. Avoid alcohol and smoking, as these can worsen stomach irritation and reduce the drug's efficacy. Maintain a healthy diet, manage stress levels, and engage in regular exercise to support overall gastrointestinal health and well-being. Also, elevating the head of your bed can help prevent nighttime reflux.

• NEXPRO L CAPSULE 10'S can be taken with or without food. However, it is generally recommended to take it before a meal, preferably in the morning. This helps to reduce acid production in the stomach effectively. If you experience stomach upset, taking it with food might help.
• Avoid consuming large meals or high-fat foods shortly before or after taking NEXPRO L CAPSULE 10'S as this can reduce the absorption of the medicine.