NISUL S TABLET 10'S

How NISUL S TABLET 10'S Works

• NISUL S TABLET 10'S is a combination medication formulated to alleviate pain and inflammation. It contains two active ingredients: Nimesulide and Serratiopeptidase. Each component contributes uniquely to the overall therapeutic effect.
• Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) that primarily works by inhibiting the production of prostaglandins. Prostaglandins are chemicals in the body that contribute to pain, inflammation, and fever. Nimesulide selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, which is mainly responsible for producing prostaglandins at the site of inflammation. By blocking COX-2, Nimesulide effectively reduces the synthesis of prostaglandins, leading to a decrease in pain and inflammation. Unlike some other NSAIDs, Nimesulide exhibits a relatively weaker effect on the COX-1 enzyme, which is involved in maintaining the normal physiological functions of the stomach and kidneys, potentially resulting in a lower risk of gastrointestinal side effects.
• Serratiopeptidase is a proteolytic enzyme, meaning it breaks down proteins. It possesses anti-inflammatory and anti-edemic (reduces swelling) properties. Serratiopeptidase aids in the breakdown of certain proteins involved in the inflammatory process, such as bradykinin, fibrin, and some other inflammatory mediators. By degrading these proteins, Serratiopeptidase helps reduce swelling, improve tissue repair, and alleviate pain. It also enhances the penetration of antibiotics and other medications into the affected tissues, promoting faster healing.
• In synergy, Nimesulide and Serratiopeptidase address pain and inflammation through complementary mechanisms. Nimesulide tackles the production of inflammatory mediators, while Serratiopeptidase facilitates the breakdown of existing inflammatory proteins and promotes tissue repair. This dual action makes NISUL S TABLET 10'S effective in managing pain and inflammation associated with various conditions like osteoarthritis, rheumatoid arthritis, post-operative pain, and dental pain. The combined action helps to reduce pain, swelling, and inflammation more effectively than either drug could achieve alone. It's crucial to use this medication as directed by a healthcare professional to maximize its benefits and minimize potential side effects.

Like all medicines, NISUL S TABLET 10'S can cause side effects, although not everybody gets them. **Common Side Effects:** * Nausea * Vomiting * Diarrhea * Stomach pain * Heartburn * Loss of appetite * Headache * Dizziness * Drowsiness **Uncommon Side Effects:** * Constipation * Gas * Mouth ulcers * Skin rash * Itching * Swelling of the face, hands, or feet * Increased sweating * Anxiety * Insomnia (difficulty sleeping) * Tingling or numbness in the hands or feet * Blurred vision * Ringing in the ears * Changes in liver function tests **Rare Side Effects:** * Serious allergic reactions (anaphylaxis) * Liver damage * Kidney problems * High blood pressure * Heart failure * Stomach ulcers or bleeding * Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) * Blood disorders (e.g., anemia, low white blood cell count) * Depression * Confusion * Memory problems **If you experience any of these side effects, especially if they are severe or persistent, stop taking NISUL S TABLET 10'S and consult your doctor immediately.**

• If you miss a dose of Nisul S Tablet 10's, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep NISUL S TAB 1X10 away from the reach of children and pets.
• Store NISUL S TAB 1X10 at room temperature.

• Take NISUL S Tablet as prescribed by your doctor. Do not exceed the recommended dosage, as it can increase the risk of side effects. Typically, it is taken once or twice daily after meals to minimize stomach upset.
• Inform your doctor about all other medications, supplements, or herbal products you are currently taking before starting NISUL S Tablet. This is crucial to avoid potential drug interactions that could reduce effectiveness or increase adverse effects. Be particularly cautious if you are on blood thinners or other NSAIDs.
• If you experience any persistent side effects such as stomach pain, nausea, heartburn, or skin rash, discontinue use and consult your doctor immediately. Prolonged use of NISUL S Tablet can sometimes lead to gastrointestinal issues or allergic reactions, which need prompt medical attention. Regular monitoring can help catch complications early.
• NISUL S Tablet provides temporary relief from pain and inflammation. It's important to address the underlying cause of your condition. Consult your doctor for a comprehensive treatment plan, which may include physical therapy, lifestyle changes, or other medications, for long-term management.
• Store NISUL S Tablets in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Always check the expiry date before using the medicine. Proper storage ensures the medication remains effective and safe for use. Discard expired medicines responsibly.

• It is recommended to take NISUL S TABLET 10'S after food to avoid stomach upset. However, consult your doctor for personalized advice.