NUPHOS 500 INJECTION
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NUPHOS 500 INJECTION
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NUPHOS 500 INJECTION

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NUPHOS 500 INJECTION

By ZEE LABORATORIES LTD

MRP

₹

82.2

₹69.87

15 % OFF

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Product DetailsArrow

About NUPHOS 500 INJECTION

  • NUPHOS 500 INJECTION is an anticancer medication utilized in the management of various malignancies. Malignancies arise from the abnormal and uncontrolled proliferation of cells, leading to the development of cancerous tumors and their potential spread throughout the body. This injection contains cyclophosphamide, a potent alkylating agent. Cyclophosphamide functions by cross-linking strands of DNA within cancer cells, thereby disrupting their structure and function. This ultimately leads to the death of the cancerous cells.
  • NUPHOS 500 INJECTION finds application in treating malignant lymphomas, a group of cancers originating in the lymphatic system. These lymphomas include Hodgkin’s disease, lymphocytic lymphoma, and mixed-cell type lymphoma. Additionally, it's employed in the treatment of leukemias, neuroblastoma, ovarian cancer, retinoblastoma, and breast carcinoma. In pediatric patients, NUPHOS 500 INJECTION can also be used to manage Minimal Change Nephrotic Syndrome, a kidney disorder characterized by substantial protein loss in the urine. This medication is often part of a comprehensive treatment plan, potentially involving other chemotherapeutic agents and therapies.
  • However, the use of NUPHOS 500 INJECTION is contraindicated in certain situations. These include pregnancy, acute infections, urinary tract infections, urinary outflow obstruction, and pre-existing bone marrow disorders. Treatment with this medication carries the risk of immune suppression, increasing susceptibility to infections. It can also lead to bone marrow failure, cardiotoxicity (damage to the heart), renal toxicity (damage to the kidneys), pulmonary toxicity (damage to the lungs), and the potential development of secondary malignancies. Therefore, it is crucial to inform your doctor about any pre-existing medical conditions, particularly kidney disease, immune disorders, cardiac conditions, or liver diseases, to ensure safe and effective treatment.
  • It is also important to be aware of potential side effects and to immediately report any unusual symptoms to your healthcare provider. Regular monitoring of blood counts and organ function is necessary during treatment with NUPHOS 500 INJECTION. The dosage and duration of treatment are determined by the physician based on the individual's condition and response to therapy. Hydration and supportive care are important components of managing potential side effects and improving treatment outcomes.

Uses of NUPHOS 500 INJECTION

  • Malignant lymphomas are cancers that begin in the lymphatic system, which is part of the body's immune system. These lymphomas can spread throughout the body, affecting lymph nodes and other organs.
  • Leukemias are cancers of the blood and bone marrow, characterized by the overproduction of abnormal white blood cells. These cells crowd out healthy blood cells, leading to various complications.
  • Retinoblastoma is a rare form of cancer that develops in the retina, the light-sensitive tissue at the back of the eye. It primarily affects young children and can lead to vision loss if left untreated.
  • Carcinoma of the breast, commonly known as breast cancer, is a malignant tumor that develops in the breast tissue. Early detection and treatment are crucial for improving outcomes.
  • Ovarian cancer is a type of cancer that begins in the ovaries. It often goes undetected until it has spread to other parts of the body, making it more difficult to treat.
  • Mycosis fungoides is a type of cutaneous T-cell lymphoma, a rare form of non-Hodgkin lymphoma that affects the skin. It typically presents with skin lesions that can progress over time.
  • Minimal Change Nephrotic Syndrome in Pediatric Patients is a kidney disorder characterized by damage to the glomeruli, leading to protein leakage in the urine. It is a common cause of nephrotic syndrome in children.

Side Effects of NUPHOS 500 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, but not everyone experiences them. NUPHOS 500 INJECTION can cause both serious and common side effects.

  • Infections
  • Immune suppression
  • Blood disorders
  • Allergic reactions
  • Abnormal liver function
  • Inflammation of the bladder
  • Kidney diseases
  • blood in urine
  • sterility
  • impaired wound healing
  • Nausea, vomiting
  • Low white blood cell count
  • Diarrhea
  • Hair loss
  • Fever
  • Weakness
  • Inflammation
  • Dizziness
  • Blurred vision
  • amenorrhea

Safety Advice for NUPHOS 500 INJECTIONArrow

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Pregnancy

UNSAFE

NUPHOS 500 INJECTION can cause fetal harm when administered to the pregnant woman. Inform your physician if you are pregnant or planning to get pregnant before taking this medication. Your physician will instruct you to take when it is necessary.

Dosage of NUPHOS 500 INJECTIONArrow

  • NUPHOS 500 INJECTION should be administered intravenously under the supervision of physicians experienced in cancer chemotherapy. The dosage and administration schedule depend heavily on the specific chemotherapy protocol being used, the type of cancer being treated, the patient's overall health, and their response to the treatment.
  • Prior to each administration of NUPHOS 500 INJECTION, a thorough assessment of the patient's blood counts, kidney function, and liver function is crucial. Dosage adjustments may be necessary based on these parameters to minimize the risk of potential toxicities. Adequate hydration should be maintained before, during, and after the infusion to help protect the kidneys.
  • The injection must be given via intravenous infusion, never as a rapid bolus injection. The infusion rate must adhere strictly to the established guidelines in the chemotherapy protocol. Patients should be monitored closely during the infusion for signs of allergic reactions or other adverse effects. Emergency equipment and medications should be readily available to manage such reactions promptly.
  • It is important to note that the dosage recommendations provided here are general guidelines only and should be adjusted by a qualified oncologist based on the individual patient's needs and tolerance. Always consult the prescribing information and relevant medical literature for complete and up-to-date dosing instructions.

How to store NUPHOS 500 INJECTION?Arrow

  • Keep NUPHOS 500MG INJ away from the reach of children and pets.
  • Store NUPHOS 500MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of NUPHOS 500 INJECTIONArrow

  • NUPHOS 500 INJECTION is thought to exert its anti-cancer effects by directly interfering with the DNA of tumor cells. Specifically, it causes cross-linking between DNA strands. This cross-linking disrupts the normal function of the DNA, preventing the tumor cells from replicating and multiplying. The damage inflicted upon the DNA ultimately leads to the death of these rapidly dividing cancer cells. This mechanism of action makes NUPHOS 500 INJECTION a valuable tool in chemotherapy regimens aimed at controlling and eradicating cancerous growths. By targeting the very core of the tumor cell's ability to proliferate, this medication helps to slow down disease progression and improve patient outcomes. The precise way this drug interacts with DNA is still under investigation, but current understanding highlights its crucial role in disrupting cancer cell division.
  • NUPHOS 500 INJECTION works by creating bonds between DNA strands within cancer cells. This process, known as cross-linking, interferes with the cell's ability to replicate its DNA accurately during cell division. Because cancer cells divide rapidly, they are more susceptible to DNA damage than healthy cells. The cross-linking caused by NUPHOS 500 INJECTION prevents the cancer cells from properly duplicating their genetic material, ultimately leading to cell death. This targeted approach helps to eliminate cancer cells while minimizing damage to healthy tissues. Ongoing research continues to explore the precise mechanisms by which this drug interacts with DNA and its potential for further therapeutic applications.
  • The cross-linking action of NUPHOS 500 INJECTION on DNA inhibits the cell's natural repair mechanisms. When DNA is damaged, cells typically activate processes to fix the damage. However, the extensive cross-linking caused by this medication overwhelms these repair systems in cancer cells. Unable to repair the DNA damage, the cancer cells undergo programmed cell death (apoptosis). This process ensures that the damaged cells are eliminated, preventing them from further proliferation and spread. This ability to disrupt DNA repair mechanisms contributes significantly to the effectiveness of NUPHOS 500 INJECTION in treating various types of cancer.

How to use NUPHOS 500 INJECTIONArrow

  • NUPHOS 500 INJECTION must be administered intravenously under the direct supervision of physicians who are thoroughly experienced and qualified in the use of cancer chemotherapeutic agents. Due to the potential for serious adverse reactions, including infusion-related reactions, it is crucial that the injection is given in a setting where appropriate resuscitation equipment is immediately available.
  • The dosage and administration schedule of NUPHOS 500 INJECTION will be determined by the treating physician, taking into account various factors such as the patient's body surface area, the specific type and stage of cancer being treated, and the patient's overall health and tolerance to the medication. It is essential to strictly adhere to the prescribed dosage and administration schedule to optimize the therapeutic benefits and minimize the risk of potential side effects.
  • Prior to each administration of NUPHOS 500 INJECTION, patients should undergo thorough assessment to ensure they are fit to receive the medication. This may involve blood tests, physical examinations, and evaluation of organ function. Close monitoring of the patient's vital signs, including blood pressure, heart rate, and respiratory rate, is necessary throughout the infusion process. Any signs of adverse reactions should be promptly addressed by the medical team.

FAQs

Is NUPHOS 500 INJECTION chemotherapy medication?Arrow

Yes, NUPHOS 500 INJECTION is a chemotherapy medicine and it works by killing cancer cells. It prevents the spreading of cancer cells to different parts.

Can NUPHOS 500 INJECTION cause weight loss?Arrow

Yes, NUPHOS 500 INJECTION causes weight loss due to reduced appetite and consult the doctor if there is excessive weight loss.

Are there any drug interactions with NUPHOS 500 INJECTION?Arrow

There are no known drug interactions with NUPHOS 500 INJECTION.

What precautions should I take while taking NUPHOS 500 INJECTION?Arrow

Inform the doctor if the patient has any kidney, liver, heart problems and medication taken for different medical conditions. Avoid this medication if the patient is pregnant or breastfeeding mother. The patient undergoing treatment with this medicine may have dizziness, blurred vision. Consult your doctor before driving and handling heavy machines.

What molecule is used to make NUPHOS 500 INJECTION?Arrow

NUPHOS 500 INJECTION is made using the molecule CYCLOPHOSPHAMIDE.

For what ailments is NUPHOS 500 INJECTION prescribed?Arrow

NUPHOS 500 INJECTION is prescribed for Oncology related ailments.

References

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Baxter, Electronic medicines compendium (emc),

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Baxter, US Food and Drug Administration,

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Ratings & Review

Discount on medicine is good But OTC discount is zero and very low

Abhishek Solanki

•

Reviewed on 05-12-2022

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(3/5)

Good series, satisfied customer

Sameer Jadhav

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Reviewed on 06-01-2024

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(5/5)

Medkart is very good for generic medicines

DD Sanghavi

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Reviewed on 14-07-2023

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(3/5)

Excellent service

Ali Akhtar

•

Reviewed on 26-07-2023

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(5/5)

medkart pharmacy medicine is very nice 👍

Sagar Christian

•

Reviewed on 27-11-2023

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(5/5)

Marketer / Manufacturer Details

ZEE LABORATORIES LTD

Country of Origin -

India

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