OLMEZEST AZ 20MG TABLET 10'S

How OLMEZEST AZ 20MG TABLET 10'S Works

• OLMEZEST AZ 20MG TABLET 10'S is a combination medication designed to effectively manage hypertension, or high blood pressure. It combines the actions of two active ingredients: Olmesartan and Azelnidipine. Understanding how each component works is crucial to appreciating the overall effectiveness of this medication.
• Olmesartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). To understand its action, it's important to know about the renin-angiotensin-aldosterone system (RAAS). This system plays a vital role in regulating blood pressure. When blood pressure drops, the kidneys release renin, which triggers a cascade of events leading to the production of angiotensin II. Angiotensin II causes blood vessels to constrict (narrow), increasing blood pressure. It also stimulates the release of aldosterone, which causes the kidneys to retain sodium and water, further increasing blood volume and blood pressure. Olmesartan works by selectively blocking the angiotensin II receptors. By blocking these receptors, Olmesartan prevents angiotensin II from constricting blood vessels. This allows the blood vessels to relax and widen, resulting in a decrease in blood pressure. Furthermore, by blocking angiotensin II's action on aldosterone release, Olmesartan reduces sodium and water retention, further contributing to blood pressure reduction.
• Azelnidipine is a dihydropyridine calcium channel blocker (DHP CCB). Calcium channel blockers work by preventing calcium from entering smooth muscle cells in the walls of blood vessels. Calcium is essential for muscle contraction. When calcium enters these cells, it causes the muscles to contract, leading to vasoconstriction (narrowing of blood vessels). Azelnidipine selectively blocks L-type calcium channels in vascular smooth muscle. By blocking these channels, Azelnidipine reduces the influx of calcium into the cells. This causes the smooth muscle cells to relax, leading to vasodilation (widening of blood vessels). This vasodilation reduces peripheral resistance, which is the resistance to blood flow in the arteries. As a result, the heart doesn't have to work as hard to pump blood, and blood pressure is lowered.
• In summary, OLMEZEST AZ 20MG TABLET 10'S works through a dual mechanism of action. Olmesartan blocks the effects of angiotensin II, preventing vasoconstriction and reducing sodium and water retention. Azelnidipine blocks calcium channels, promoting vasodilation. Together, these actions synergistically lower blood pressure more effectively than either drug could achieve alone. This combination helps to relax blood vessels, reduce the workload on the heart, and lower overall blood pressure, thereby reducing the risk of cardiovascular events associated with hypertension.

Common side effects of Olmezest AZ 20mg Tablet may include dizziness, lightheadedness, headache, fatigue, nausea, vomiting, diarrhea, abdominal pain, and upper respiratory tract infection symptoms like a cough or sore throat. Less common but potentially serious side effects include allergic reactions (rash, itching, swelling), kidney problems (decreased urination, swelling of ankles/feet), changes in heart rhythm, and muscle weakness. Some individuals may experience changes in blood pressure or electrolyte imbalances. Azilsartan-specific side effects can also include angioedema (swelling of the face, lips, tongue, or throat) and sprue-like enteropathy (severe, chronic diarrhea with substantial weight loss). If you experience any unusual or severe symptoms while taking this medication, seek immediate medical attention.

• If you miss a dose of Olmezest AZ 20mg Tablet, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep OLMEZEST AZ 20MG TAB 1X10 away from the reach of children and pets.
• Store OLMEZEST AZ 20MG TAB 1X10 at room temperature.

• **Take OLMEZEST AZ 20MG TABLET 10'S as prescribed:** Always follow your doctor's instructions regarding dosage and timing. Do not alter the dose or stop taking the medication without consulting your healthcare provider, even if you feel better.
• **Consistency is Key:** Take OLMEZEST AZ 20MG TABLET 10'S at the same time each day to maintain a consistent level of medication in your bloodstream. This helps to manage your blood pressure more effectively. Setting a daily reminder can be useful.
• **Monitor Your Blood Pressure Regularly:** Keep track of your blood pressure readings at home and share them with your doctor. This helps them assess the effectiveness of the medication and make any necessary adjustments to your treatment plan. It also helps in identifying potential issues early on.
• **Lifestyle Modifications Enhance Effectiveness:** Complement the effects of OLMEZEST AZ 20MG TABLET 10'S with healthy lifestyle choices. These include adopting a balanced diet low in sodium and rich in fruits, vegetables, and whole grains; engaging in regular physical activity such as brisk walking or cycling for at least 30 minutes most days of the week; limiting alcohol consumption; and quitting smoking. These changes synergistically lower blood pressure and improve cardiovascular health.
• **Be Aware of Potential Side Effects:** While OLMEZEST AZ 20MG TABLET 10'S is generally well-tolerated, be aware of possible side effects such as dizziness, lightheadedness, or changes in kidney function. If you experience any unusual or bothersome symptoms, contact your doctor promptly for guidance. They can assess the situation and provide appropriate recommendations. Staying hydrated can also help mitigate some side effects, but discuss this with your doctor first.

• OLMEZEST AZ 20MG TABLET 10'S can be taken with or without food. However, it is important to take it at the same time each day to maintain consistent blood levels and maximize its effectiveness. Avoid consuming high amounts of potassium-rich foods or salt substitutes containing potassium unless specifically directed by your doctor.