PREGASON TOTAL TABLET 10'S

How PREGASON TOTAL TABLET 10'S Works

• PREGASON TOTAL TABLET 10'S is a comprehensive formulation designed to address various aspects of nerve health and overall well-being. Its effectiveness stems from the synergistic action of its key ingredients: Pregabalin, Methylcobalamin, Alpha Lipoic Acid, Folic Acid, Pyridoxine, and Vitamin D3. Each component plays a distinct yet interconnected role in alleviating neuropathic pain, supporting nerve regeneration, and promoting optimal nerve function.
• Pregabalin, a crucial component of PREGASON TOTAL, functions as an anticonvulsant and analgesic. It primarily works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding modulates calcium influx at nerve terminals, subsequently reducing the release of excitatory neurotransmitters such as glutamate, noradrenaline, and substance P. By decreasing the levels of these neurotransmitters, Pregabalin effectively diminishes the over-excitation of nerve cells, leading to a reduction in neuropathic pain signals. This mechanism is particularly beneficial in conditions like diabetic neuropathy, postherpetic neuralgia, and fibromyalgia, where nerve damage or dysfunction causes chronic pain.
• Methylcobalamin, an active form of Vitamin B12, plays a vital role in nerve myelination and regeneration. It participates in the synthesis of myelin, the protective sheath surrounding nerve fibers. Adequate myelination ensures efficient nerve signal transmission. In conditions like peripheral neuropathy, nerve damage can lead to demyelination, impairing nerve function. Methylcobalamin supplementation helps to restore myelin integrity, improving nerve conduction velocity and reducing neuropathic symptoms such as numbness, tingling, and burning sensations. Additionally, Methylcobalamin acts as a cofactor in various enzymatic reactions involved in cellular metabolism and DNA synthesis, contributing to overall nerve health.
• Alpha Lipoic Acid (ALA) is a potent antioxidant that protects nerve cells from oxidative stress and damage. Oxidative stress, caused by an imbalance between free radical production and antioxidant defenses, can contribute to nerve dysfunction in conditions like diabetic neuropathy. ALA scavenges free radicals and reduces oxidative damage to nerve tissues. Moreover, ALA improves nerve blood flow, ensuring adequate oxygen and nutrient supply to nerve cells. It also enhances insulin sensitivity, which is particularly beneficial in diabetic neuropathy. By reducing oxidative stress, improving blood flow, and enhancing insulin sensitivity, ALA promotes nerve healing and reduces neuropathic symptoms.
• Folic Acid (Vitamin B9) and Pyridoxine (Vitamin B6) are essential B vitamins that play crucial roles in nerve health. Folic acid is involved in DNA synthesis and repair, which are vital for nerve cell growth and regeneration. Pyridoxine acts as a cofactor in the synthesis of neurotransmitters such as serotonin, dopamine, and GABA, which regulate mood, pain perception, and nerve excitability. Deficiencies in these B vitamins can contribute to nerve damage and neuropathic symptoms. Supplementation with folic acid and pyridoxine helps to maintain optimal nerve function and reduce neuropathic pain.
• Vitamin D3, a fat-soluble vitamin, has been shown to have neuroprotective effects. Vitamin D receptors are present in various brain regions, suggesting a role for Vitamin D in nerve function. Vitamin D3 may modulate calcium signaling, regulate nerve growth factors, and reduce inflammation in the nervous system. Vitamin D deficiency has been linked to an increased risk of neuropathic pain and other neurological disorders. Supplementation with Vitamin D3 helps to maintain optimal nerve health and reduce neuropathic symptoms.
• In summary, PREGASON TOTAL TABLET 10'S works through a multi-pronged approach. Pregabalin reduces the release of excitatory neurotransmitters, Methylcobalamin supports nerve myelination, Alpha Lipoic Acid protects against oxidative stress, Folic Acid and Pyridoxine support nerve cell growth and neurotransmitter synthesis, and Vitamin D3 provides neuroprotective effects. This comprehensive formulation addresses various underlying mechanisms of neuropathic pain and promotes overall nerve health and function, leading to significant symptom relief and improved quality of life for individuals suffering from nerve-related conditions.

Possible side effects of Pregason Total Tablet may include: * **Common:** Dizziness, drowsiness, headache, nausea, vomiting, dry mouth, constipation, blurred vision, weight gain, edema (swelling), difficulty concentrating, memory problems, increased appetite, feeling drunk, tremor, fatigue, confusion, decreased libido. * **Uncommon:** Mood changes (depression, anxiety, euphoria), sleep disturbances (insomnia), nervousness, paresthesia (numbness or tingling), incoordination, speech disorder, myoclonus (muscle twitching), hyporeflexia (decreased reflexes), increased or decreased heart rate, changes in blood pressure, muscle weakness or pain, joint pain, back pain, vision changes, ringing in the ears (tinnitus), skin rash, itching, sweating, breast enlargement (in both men and women), sexual dysfunction, allergic reactions. * **Rare:** Serious allergic reactions (anaphylaxis), liver problems, jaundice, blood disorders, severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), rhabdomyolysis (muscle breakdown), suicidal thoughts or behavior. **Note:** This is not an exhaustive list, and other side effects may occur. If you experience any unusual or bothersome symptoms, consult your doctor or pharmacist.

• If you miss a dose of Pregason Total Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the one you missed.

• Keep PREGASON TOTAL TAB 1X10 away from the reach of children and pets.
• Store PREGASON TOTAL TAB 1X10 at room temperature.

• Take PREGASON TOTAL TABLET 10'S as directed by your doctor. Adhere strictly to the prescribed dosage and duration to maximize its benefits in managing neuropathic pain and nutritional deficiencies. Consistent use is key for optimal results. Do not alter the dosage without consulting your healthcare provider.
• For best absorption of nutrients like Methylcobalamin, Alpha Lipoic Acid, and Folic Acid present in PREGASON TOTAL TABLET 10'S, take it with a meal. This helps enhance the bioavailability of these essential components, ensuring your body utilizes them effectively. Avoid taking it on an empty stomach unless advised otherwise by your doctor.
• Inform your doctor about all medications, supplements, and herbal products you are currently taking before starting PREGASON TOTAL TABLET 10'S. This is crucial to avoid potential drug interactions that could affect the efficacy of the treatment or lead to adverse effects. Include even over-the-counter medications in your disclosure.
• If you experience any persistent side effects such as nausea, stomach upset, or allergic reactions after taking PREGASON TOTAL TABLET 10'S, consult your doctor immediately. Prompt reporting of side effects can help in timely management and prevent complications. Do not ignore any unusual symptoms.
• Store PREGASON TOTAL TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Proper storage ensures the medication remains effective and safe for consumption. Keep it out of reach of children to prevent accidental ingestion.

• PREGASON TOTAL TABLET 10'S does not typically have significant interactions with food. It can be taken with or without food. However, taking it with food might help reduce potential stomach upset in some individuals. Always follow your doctor's instructions regarding dosage and timing.