RETOZ MR 4MG TABLET 10'S

How RETOZ MR 4MG TABLET 10'S Works

• RETOZ MR 4MG Tablet is a combination medication containing Thiocolchicoside and Etoricoxib. It is primarily used to relieve muscle spasm associated with pain and inflammation.
• Thiocolchicoside is a muscle relaxant that works by acting on GABA receptors in the brain and spinal cord. GABA (gamma-aminobutyric acid) is a neurotransmitter that inhibits nerve transmission in the brain. By enhancing GABA's effects, Thiocolchicoside helps to reduce muscle stiffness and spasm. Specifically, it is believed to act as a competitive GABA-A receptor agonist, meaning it binds to the same site as GABA and enhances its inhibitory effects. It also blocks glycine receptors, which further contributes to its muscle-relaxant properties. This dual mechanism helps to alleviate muscle spasm and improve mobility.
• Etoricoxib is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the class of selective COX-2 inhibitors. It works by blocking the action of cyclooxygenase-2 (COX-2) enzymes, which are responsible for producing prostaglandins. Prostaglandins are hormone-like substances that contribute to inflammation, pain, and fever. By inhibiting COX-2, Etoricoxib reduces the production of prostaglandins, thereby alleviating pain and inflammation.
• In summary, RETOZ MR 4MG Tablet works by combining the muscle-relaxant effects of Thiocolchicoside, which acts on GABA receptors to reduce muscle stiffness and spasm, with the anti-inflammatory and analgesic effects of Etoricoxib, which inhibits COX-2 enzymes to reduce pain and inflammation. This dual action helps to provide relief from muscle spasm associated with pain and inflammation, improving overall comfort and mobility for the patient.

Common side effects of RETOZ MR 4MG TABLET may include nausea, vomiting, heartburn, diarrhea, stomach pain, loss of appetite, dry mouth, increased sweating, dizziness, drowsiness, weakness, headache, nervousness, confusion, difficulty in concentration, blurred vision, insomnia, tremor, and muscle spasm. Less common or rare side effects may include allergic reactions (rash, itching, swelling), changes in blood pressure, abnormal liver function tests, and gastrointestinal bleeding. This is not an exhaustive list, and other side effects may occur. Consult your doctor if you experience any troublesome symptoms.

• If you miss a dose of RETOZ MR 4MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to catch up.

• Keep RETOZ MR 4MG TAB 1X10 away from the reach of children and pets.
• Store RETOZ MR 4MG TAB 1X10 at room temperature.

• RETOZ MR 4MG TABLET 10'S is typically prescribed to alleviate muscle spasm-related pain and discomfort. Follow your doctor's instructions regarding dosage and duration to maximize its effectiveness.
• To minimize potential stomach upset, take RETOZ MR 4MG TABLET 10'S with food or immediately after meals. This can help reduce the likelihood of gastrointestinal side effects.
• Avoid alcohol consumption while taking RETOZ MR 4MG TABLET 10'S, as it can enhance the sedative effects of the medication, leading to increased drowsiness and impaired coordination. This combination can be dangerous.
• Be cautious when operating heavy machinery or driving after taking RETOZ MR 4MG TABLET 10'S. The medication may cause drowsiness or dizziness, affecting your ability to perform tasks that require alertness.
• If you experience any persistent or bothersome side effects, such as severe dizziness, allergic reactions (rash, itching, swelling), or unusual changes in mood, consult your doctor promptly. Do not adjust the dosage without medical advice.

• RETOZ MR 4MG TABLET 10'S can be taken with or without food. However, it is best to take it at a fixed time to maintain consistent blood levels of the medicine. Avoid consuming large amounts of grapefruit juice while taking this medication, as it may increase the concentration of the drug in your body and potentially increase side effects. Always follow your doctor's instructions regarding food and drink.