SIAGLIDE M 50/500MG TABLET 15'S

How SIAGLIDE M 50/500MG TABLET 15'S Works

• SIAGLIDE M 50/500MG TABLET is a combination medication containing sitagliptin and metformin. It is primarily prescribed to manage type 2 diabetes mellitus by effectively controlling blood sugar levels. To understand how SIAGLIDE M works, it's essential to break down the actions of its two active ingredients: sitagliptin and metformin.
• **Sitagliptin:** Sitagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that inactivates incretin hormones. Incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), play a crucial role in regulating blood sugar. They stimulate insulin release from the pancreas when blood sugar is high and suppress glucagon secretion (a hormone that raises blood sugar) when blood sugar is low. By inhibiting DPP-4, sitagliptin increases the levels of active incretin hormones in the body. This, in turn, enhances insulin secretion in response to high blood sugar and reduces glucagon secretion, leading to better blood sugar control. Essentially, sitagliptin works by boosting the body's own ability to regulate glucose levels.
• **Metformin:** Metformin is a biguanide and works through several mechanisms to lower blood sugar. Firstly, it decreases glucose production in the liver. The liver is a significant source of glucose in the body, and metformin helps to reduce the amount of glucose released into the bloodstream. Secondly, metformin increases insulin sensitivity in the body's tissues, particularly muscle tissue. This means that the body's cells become more responsive to insulin, allowing them to take up glucose from the blood more efficiently. Thirdly, metformin slows down the absorption of glucose from the intestines into the bloodstream after a meal. Overall, metformin helps to lower blood sugar levels by reducing glucose production, improving insulin sensitivity, and decreasing glucose absorption.
• In summary, SIAGLIDE M combines the actions of sitagliptin and metformin to provide comprehensive blood sugar control. Sitagliptin enhances the effects of incretin hormones, promoting insulin release and suppressing glucagon, while metformin reduces glucose production in the liver, increases insulin sensitivity, and slows glucose absorption. This dual-action approach effectively manages blood sugar levels in patients with type 2 diabetes. It is usually prescribed along with diet and exercise.
• Always take SIAGLIDE M 50/500MG TABLET as prescribed by your doctor. Dosage and timing may vary depending on individual needs and other medical conditions. Regular monitoring of blood sugar levels is important while taking this medication.

Possible side effects of SIAGLIDE M 50/500MG TABLET may include: * Nausea * Vomiting * Diarrhea * Abdominal pain * Loss of appetite * Metallic taste * Hypoglycemia (low blood sugar), especially when taken with other diabetes medications * Headache * Dizziness * Weakness * Fatigue * Constipation * Skin rash or itching * Vitamin B12 deficiency (with long-term use) * Lactic acidosis (rare but serious). Seek immediate medical attention if you experience symptoms like: muscle cramps, severe tiredness, trouble breathing, stomach pain with nausea and vomiting, or a fast/irregular heartbeat. * Upper respiratory tract infection * Edema (swelling)

• If you miss a dose of SIAGLIDE M 50/500MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SIAGLIDE M 50/500MG TAB 1X15 away from the reach of children and pets.
• Store SIAGLIDE M 50/500MG TAB 1X15 at room temperature.

• Take Siaglide M 50/500mg Tablet as prescribed by your doctor, usually once or twice daily, with meals to minimize stomach upset. Consistency is key for optimal blood sugar control.
• Monitor your blood sugar levels regularly as directed by your healthcare provider. This helps track how well the medication is working and allows for dosage adjustments if needed. Keep a log to share with your doctor.
• Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity. Siaglide M works best when combined with lifestyle modifications. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, rapid heartbeat, and confusion. Carry a source of fast-acting sugar (like glucose tablets or juice) with you at all times to treat low blood sugar promptly. Inform your family and friends about how to recognize and treat hypoglycemia.
• Inform your doctor about all other medications, supplements, and herbal products you are taking before starting Siaglide M. Certain medications can interact with Siaglide M, affecting its efficacy or increasing the risk of side effects. Do not stop taking this medication without consulting your doctor.
• Stay hydrated by drinking plenty of water throughout the day. Adequate hydration supports kidney function, which is important when taking medications like Siaglide M. Aim for at least 8 glasses of water daily, unless otherwise advised by your doctor.
• Attend all scheduled follow-up appointments with your doctor and lab appointments. These appointments are essential for monitoring your progress and ensuring the medication is safe and effective for you. Your doctor may adjust your dosage based on your blood sugar levels and overall health.
• Store Siaglide M 50/500mg Tablet in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage helps maintain the medication's potency and effectiveness.
• If you experience any persistent or bothersome side effects, such as nausea, diarrhea, or abdominal pain, contact your doctor promptly. They can assess your symptoms and provide appropriate guidance. Do not self-treat without consulting your doctor.
• Understand that Siaglide M is not a cure for diabetes but helps manage blood sugar levels. It's crucial to continue following your doctor's recommendations for diet, exercise, and medication to maintain long-term health.

• SIAGLIDE M 50/500MG TABLET 15'S should be taken with food to decrease the chance of an upset stomach. Consistent timing with meals is important. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis (a serious metabolic complication) and also affect blood sugar levels. Consult your doctor or pharmacist for specific dietary advice tailored to your individual health condition.