SYMPTA 20MG TABLET 10'S

How SYMPTA 20MG TABLET 10'S Works

• SYMPTA 20MG TABLET 10'S contains tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. It primarily works by increasing blood flow to the penis during sexual stimulation. Here's a breakdown of the mechanism:
• **1. Understanding Erectile Dysfunction (ED):** ED often occurs when the blood vessels supplying the penis narrow, limiting blood flow. This can be due to various factors, including underlying medical conditions like diabetes, high blood pressure, or high cholesterol, as well as lifestyle factors like smoking, obesity, and stress.
• **2. Role of Nitric Oxide (NO):** Sexual stimulation triggers the release of nitric oxide (NO) in the penis. NO activates an enzyme called guanylate cyclase, which then produces cyclic guanosine monophosphate (cGMP).
• **3. cGMP and Smooth Muscle Relaxation:** cGMP causes the smooth muscles in the blood vessels of the penis to relax. This relaxation allows the blood vessels to widen, increasing blood flow into the penis.
• **4. PDE5 and cGMP Breakdown:** Phosphodiesterase type 5 (PDE5) is an enzyme that breaks down cGMP. When PDE5 is active, it reduces the amount of cGMP available, causing the blood vessels to constrict and reducing blood flow.
• **5. Tadalafil's Mechanism of Action:** Tadalafil inhibits PDE5. By blocking PDE5, tadalafil prevents the breakdown of cGMP. This leads to a higher concentration of cGMP in the penis, which promotes smooth muscle relaxation and increased blood flow.
• **6. Enhanced Blood Flow and Erection:** The increased blood flow resulting from tadalafil's action helps to achieve and maintain an erection during sexual stimulation. It is important to note that tadalafil does not cause an erection on its own; sexual stimulation is required to trigger the release of NO and initiate the process.
• **7. Duration of Action:** Tadalafil has a longer duration of action compared to other PDE5 inhibitors. Its effects can last up to 36 hours, allowing for a more flexible timeframe for sexual activity. This is why it is sometimes referred to as the 'weekend pill'.
• **8. Effects on Pulmonary Arterial Hypertension (PAH):** Tadalafil is also used to treat pulmonary arterial hypertension (PAH). In PAH, the blood vessels in the lungs become narrowed and thickened, leading to high blood pressure in the lungs. Tadalafil helps to relax these blood vessels, reducing blood pressure and improving blood flow in the lungs.
• **9. Important Considerations:** Tadalafil is a prescription medication and should only be taken under the guidance of a healthcare professional. It is important to discuss any underlying medical conditions and medications you are taking with your doctor before starting tadalafil. Common side effects may include headache, flushing, nasal congestion, and muscle aches. Serious side effects are rare but can occur. Tadalafil is contraindicated in individuals taking nitrates, as the combination can cause a dangerous drop in blood pressure.

Common side effects of SYMPTA 20MG TABLET may include nausea, vomiting, diarrhea, constipation, headache, dizziness, drowsiness, fatigue, dry mouth, blurred vision, urinary retention, increased heart rate, and changes in blood pressure. Less common but potentially serious side effects can include allergic reactions (rash, itching, swelling), liver problems (jaundice, dark urine), mental/mood changes (depression, anxiety, confusion), muscle weakness, seizures, and irregular heartbeat. If you experience any unusual or severe side effects, stop taking SYMPTA 20MG TABLET and consult your doctor immediately.

• If you miss a dose of SYMPTA 20MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep SYMPTA 20MG TAB 1X10 away from the reach of children and pets.
• Store SYMPTA 20MG TAB 1X10 at room temperature.

• **Take SYMPTA 20MG TABLET 10'S as prescribed:** Always follow your doctor's instructions regarding dosage and duration. Do not self-medicate or change the dosage without consulting your healthcare provider. Consistency is key to effective treatment.
• **Be aware of potential side effects:** SYMPTA 20MG TABLET 10'S, like all medications, can cause side effects. Common side effects may include nausea, headache, or dizziness. If you experience any persistent or bothersome side effects, inform your doctor immediately. Serious side effects are rare but require immediate medical attention.
• **Maintain a healthy lifestyle:** While taking SYMPTA 20MG TABLET 10'S, adopt a healthy lifestyle by eating a balanced diet, exercising regularly, and getting enough sleep. These habits can enhance the medicine's effectiveness and improve your overall well-being. Avoid excessive alcohol consumption, as it may interact with the medication.
• **Store SYMPTA 20MG TABLET 10'S properly:** Keep the medicine in a cool, dry place, away from direct sunlight and moisture. Store it out of reach of children and pets. Check the expiration date before use and discard any expired medication safely.
• **Do not skip doses or stop taking SYMPTA 20MG TABLET 10'S abruptly:** It's crucial to take the medication as prescribed and complete the full course of treatment, even if you feel better. Skipping doses or stopping abruptly can lead to a relapse of symptoms or withdrawal effects. If you wish to discontinue the medication, consult your doctor for guidance on how to taper off gradually.
• **Inform your doctor about other medications and medical conditions:** Before starting SYMPTA 20MG TABLET 10'S, inform your doctor about any other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Also, disclose any existing medical conditions, such as liver or kidney problems, to prevent potential drug interactions or complications.

• SYMPTA 20MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood levels. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medicine, as it may increase the concentration of the drug in your body and potentially lead to increased side effects. Consult your doctor for specific dietary advice.