TENDIA P TABLET 15'S

How TENDIA P TABLET 15'S Works

• TENDIA P TABLET 15'S is a combination medication designed to effectively manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Teneligliptin and Pioglitazone, each working through distinct mechanisms to achieve optimal glycemic control.
• Teneligliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that inactivates incretin hormones. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar. They stimulate insulin release from the pancreas when blood glucose levels are high and suppress glucagon secretion (a hormone that raises blood sugar) after a meal. By inhibiting DPP-4, Teneligliptin increases the levels of active incretins in the body. This enhancement leads to increased insulin secretion and decreased glucagon secretion in a glucose-dependent manner, ultimately helping to lower blood sugar levels after meals and throughout the day.
• Pioglitazone, on the other hand, belongs to a class of drugs called thiazolidinediones (TZDs). It works primarily by improving insulin sensitivity in the body's tissues, particularly in the liver, muscle, and fat cells. Insulin resistance is a hallmark of type 2 diabetes, where the body's cells do not respond effectively to insulin, leading to elevated blood sugar levels. Pioglitazone activates a nuclear receptor called PPARγ (peroxisome proliferator-activated receptor gamma). Activation of PPARγ leads to changes in gene expression that promote glucose uptake and utilization in these tissues, reduces glucose production in the liver, and improves lipid metabolism. By making the body more sensitive to its own insulin, Pioglitazone helps to lower blood sugar levels and improve overall glycemic control.
• In summary, TENDIA P TABLET 15'S works through a dual mechanism: Teneligliptin enhances incretin activity to increase insulin secretion and decrease glucagon secretion, while Pioglitazone improves insulin sensitivity in target tissues. This synergistic action helps to lower blood sugar levels effectively in patients with type 2 diabetes. It is crucial to take this medication as prescribed by your doctor, along with lifestyle modifications such as diet and exercise, to achieve the best possible outcomes in managing your diabetes.

The following side effects may occur with TENDIA P TABLET 15'S: * **Common:** Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste. * **Uncommon:** Headache, Dizziness, Sleep disturbances (insomnia), Skin rash or itching, Fatigue, Constipation, Heartburn. * **Rare:** Liver problems (indicated by jaundice, dark urine, or persistent fatigue), Allergic reactions (swelling of the face, lips, or tongue; difficulty breathing), Low blood sugar (hypoglycemia), Muscle pain or weakness, Vision changes, Decreased blood cell counts.

• If you miss a dose of TENDIA P TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep TENDIA P TAB 1X15 away from the reach of children and pets.
• Store TENDIA P TAB 1X15 at room temperature.

• Take TENDIA P TABLET 15'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. Consistent adherence to the prescribed regimen is crucial for optimal blood sugar control and to minimize potential side effects. Missing doses can lead to fluctuations in blood sugar levels, impacting overall health.
• Monitor your blood glucose levels regularly, especially when starting TENDIA P TABLET 15'S. Keep a log of your readings and share it with your healthcare provider. This will help them assess the effectiveness of the medication and make necessary adjustments to your treatment plan. Regular monitoring also allows for early detection and management of potential hypoglycemia (low blood sugar).
• Be aware of potential side effects such as nausea, diarrhea, or headache. These are usually mild and temporary. However, if they persist or worsen, inform your doctor immediately. In rare cases, more serious side effects like lactic acidosis can occur. Seek immediate medical attention if you experience symptoms such as rapid breathing, stomach pain, muscle cramps, or unusual tiredness.
• Maintain a healthy lifestyle while taking TENDIA P TABLET 15'S. Follow a balanced diet that is low in sugar and refined carbohydrates. Engage in regular physical activity, as exercise helps improve insulin sensitivity and lowers blood sugar levels. Avoid excessive alcohol consumption, as it can interfere with blood sugar control and increase the risk of side effects. Consult a registered dietitian or certified diabetes educator for personalized guidance on diet and exercise.
• Inform all your healthcare providers that you are taking TENDIA P TABLET 15'S, especially before any surgery or medical procedure. This medication can interact with other drugs and anesthesia. Carry a medical ID or card that lists your medications and medical conditions. This will ensure that you receive appropriate care in case of an emergency. Store TENDIA P TABLET 15'S at room temperature, away from moisture and direct sunlight.

• TENDIA P TABLET 15'S can be taken with or without food. However, it is best to take it at a fixed time to maintain consistent blood sugar levels. Consult your doctor for specific dietary advice while taking this medication.