TIDOMET PLUS TABLET 10'S

How TIDOMET PLUS TABLET 10'S Works

• TIDOMET PLUS TABLET 10'S is a combination medication primarily used to manage the symptoms of Parkinson's disease. It contains three active ingredients: Levodopa, Carbidopa, and Entacapone. Each component plays a crucial role in alleviating the motor symptoms associated with Parkinson's.
• Levodopa is a precursor to dopamine, a neurotransmitter that is deficient in the brains of individuals with Parkinson's disease. Dopamine is essential for controlling movement, coordination, and other neurological functions. When Levodopa enters the brain, it is converted into dopamine, effectively replenishing the depleted levels and improving motor control. This conversion helps reduce symptoms like tremors, rigidity, and bradykinesia (slowness of movement).
• However, a significant portion of Levodopa is metabolized in the body before it can reach the brain. This is where Carbidopa comes in. Carbidopa is a dopa decarboxylase inhibitor. It inhibits the enzyme dopa decarboxylase, which is responsible for breaking down Levodopa in the peripheral tissues (outside the brain). By preventing this breakdown, Carbidopa allows more Levodopa to cross the blood-brain barrier and reach the brain, thereby increasing its effectiveness. This also reduces the side effects caused by dopamine in the periphery, such as nausea and vomiting.
• Entacapone is a catechol-O-methyltransferase (COMT) inhibitor. COMT is an enzyme that breaks down dopamine and Levodopa in the brain and peripheral tissues. By inhibiting COMT, Entacapone further reduces the breakdown of Levodopa, prolonging its duration of action and maintaining more stable dopamine levels in the brain. This helps to smooth out the motor fluctuations that can occur in Parkinson's patients as the effects of Levodopa wear off between doses – often referred to as the 'wearing-off' effect. By inhibiting both dopa decarboxylase (with Carbidopa) and COMT (with Entacapone), TIDOMET PLUS ensures that a greater and more sustained amount of Levodopa is available to the brain, leading to more consistent symptom control.
• In summary, TIDOMET PLUS TABLET 10'S works through a triple-action mechanism: Levodopa increases dopamine levels in the brain, Carbidopa prevents the peripheral breakdown of Levodopa, and Entacapone extends the duration of Levodopa's effect. This synergistic combination helps to improve motor function, reduce motor fluctuations, and enhance the overall quality of life for individuals suffering from Parkinson's disease. It is essential to take TIDOMET PLUS exactly as prescribed by your doctor to achieve the best possible results. The dosage and frequency of administration are tailored to each patient's specific needs and response to the medication.

Common side effects of Tidomet Plus Tablet may include nausea, vomiting, loss of appetite, dry mouth, dizziness, lightheadedness, drowsiness, confusion, insomnia (difficulty sleeping), vivid dreams, anxiety, agitation, headache, blurred vision, and changes in taste. Less common but more serious side effects can include hallucinations, delusions, depression, suicidal thoughts, uncontrolled movements (dyskinesia), muscle stiffness, and irregular heartbeat. Rarely, it can cause a severe allergic reaction with symptoms like rash, itching, swelling, severe dizziness, and trouble breathing. Notify your doctor immediately if you experience any unusual or severe side effects.

• If you miss a dose of Tidomet Plus Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep TIDOMET PLUS TAB 1X10 away from the reach of children and pets.
• Store TIDOMET PLUS TAB 1X10 at room temperature.

• Take TIDOMET PLUS TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, as this could worsen your condition or lead to withdrawal symptoms. Consistent adherence to the prescribed regimen is crucial for optimal therapeutic outcomes.
• Store TIDOMET PLUS TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Proper storage helps maintain the drug's efficacy and prevents accidental ingestion. Regularly check the expiration date and discard any expired medication safely.
• Be aware of potential side effects associated with TIDOMET PLUS TABLET 10'S. Common side effects may include nausea, dizziness, or changes in blood pressure. If you experience any severe or persistent side effects, such as chest pain, difficulty breathing, or allergic reactions (rash, itching, swelling), seek immediate medical attention. Inform your doctor about all side effects you encounter during treatment.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting TIDOMET PLUS TABLET 10'S. Drug interactions can affect how TIDOMET PLUS TABLET 10'S works and increase the risk of side effects. This includes over-the-counter medications and herbal remedies. A comprehensive medication history helps your doctor make informed decisions about your treatment plan.
• If you miss a dose of TIDOMET PLUS TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Missing doses can reduce the effectiveness of the medication in controlling your symptoms. Setting reminders can help maintain consistent dosing.

• TIDOMET PLUS TABLET 10'S can be taken with or without food. However, it is important to take it consistently with respect to meals, either always with food or always without food, to maintain consistent absorption of the medication. Avoid taking it with high-fat meals, as this may affect the absorption of the medicine. Consult your doctor for specific dietary advice.