TRIGLIMISAVE LS 2MG TABLET 10'S

How TRIGLIMISAVE LS 2MG TABLET 10'S Works

• TRIGLIMISAVE LS 2MG TABLET is a combination medicine designed to manage type 2 diabetes mellitus. It combines three active ingredients: glimepiride, pioglitazone, and metformin. Each component works through different mechanisms to lower blood glucose levels.
• Glimepiride belongs to the sulfonylurea class of drugs. It functions by stimulating the beta cells in the pancreas to release more insulin. Insulin is a hormone that helps glucose move from the blood into cells, where it's used for energy. By increasing insulin secretion, glimepiride effectively lowers blood sugar levels, particularly after meals.
• Pioglitazone is a thiazolidinedione (TZD) that enhances insulin sensitivity in the body's tissues, primarily in muscle and fat. It works by activating peroxisome proliferator-activated receptor gamma (PPARγ), a nuclear receptor that regulates genes involved in glucose and lipid metabolism. This activation leads to improved insulin utilization, reducing insulin resistance and lowering blood glucose levels. Pioglitazone also helps to decrease the production of glucose in the liver.
• Metformin is a biguanide that primarily reduces glucose production in the liver and improves insulin sensitivity. It decreases hepatic glucose output by inhibiting gluconeogenesis (the production of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, metformin enhances glucose uptake and utilization by peripheral tissues, contributing to lower blood sugar levels. It also slows down the absorption of glucose from the intestines after a meal.
• In summary, TRIGLIMISAVE LS 2MG TABLET works through a triple-pronged approach: glimepiride increases insulin release, pioglitazone improves insulin sensitivity and reduces liver glucose production, and metformin reduces liver glucose production and enhances peripheral glucose uptake. This synergistic action helps to effectively control blood sugar levels in patients with type 2 diabetes mellitus.

Possible side effects of TRIGLIMISAVE LS 2MG TABLET may include: Hypoglycemia (low blood sugar), Nausea, Diarrhea, Abdominal pain, Vomiting, Headache, Dizziness, Allergic reactions (skin rash, itching, hives), Weight gain, Edema (swelling), Liver problems (rare), Visual disturbances, Metallic taste, Constipation, Flatulence, Heartburn. Contact your doctor if you experience any severe or persistent side effects.

• If you miss a dose of TRIGLIMISAVE LS 2MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep TRIGLIMISAVE LS 2MG TAB 1X10 away from the reach of children and pets.
• Store TRIGLIMISAVE LS 2MG TAB 1X10 at room temperature.

• Take TRIGLIMISAVE LS 2MG TABLET 10'S as prescribed by your doctor, usually once daily. It's crucial to follow the dosage and timing instructions for optimal blood sugar control. Consistency is key, so try to take it at the same time each day.
• TRIGLIMISAVE LS 2MG TABLET 10'S works best when combined with a healthy lifestyle. Focus on a balanced diet rich in fruits, vegetables, and whole grains, while limiting sugary and processed foods. Regular physical activity, such as brisk walking or cycling, can also significantly improve blood sugar levels.
• Monitor your blood sugar levels regularly as advised by your healthcare provider while taking TRIGLIMISAVE LS 2MG TABLET 10'S. Keeping a log of your readings can help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Report any unusual fluctuations or concerns to your doctor promptly.
• Be aware of the potential side effects of TRIGLIMISAVE LS 2MG TABLET 10'S, such as hypoglycemia (low blood sugar). Learn to recognize the symptoms of hypoglycemia, including shakiness, sweating, dizziness, and confusion. Always carry a quick source of sugar, like glucose tablets or fruit juice, to treat a hypoglycemic episode promptly. Inform your family and friends about the signs of hypoglycemia and how to assist you if needed.
• Inform your doctor about all other medications, supplements, and herbal remedies you are taking before starting TRIGLIMISAVE LS 2MG TABLET 10'S. Certain medications can interact with TRIGLIMISAVE LS 2MG TABLET 10'S, potentially affecting its effectiveness or increasing the risk of side effects. It's essential to provide your doctor with a complete medical history to ensure safe and effective treatment.

• TRIGLIMISAVE LS 2MG TABLET 10'S may be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood sugar levels. If you experience nausea or stomach upset, taking it with food may help.