ALGIDUO SYRUP 150 ML

How ALGIDUO SYRUP 150 ML Works

• ALGIDUO SYRUP 150 ML is a carefully formulated medication designed to provide effective relief from pain and fever, particularly in children. Its efficacy stems from the synergistic action of its two primary active ingredients: Paracetamol and Mefenamic Acid. Understanding how these ingredients work individually and together provides insight into the syrup's therapeutic benefits.
• Paracetamol, also known as acetaminophen, is a widely used analgesic (pain reliever) and antipyretic (fever reducer). Its mechanism of action primarily involves inhibiting the production of prostaglandins in the brain and spinal cord. Prostaglandins are substances that contribute to pain and inflammation. By reducing prostaglandin synthesis, Paracetamol effectively diminishes pain signals and lowers body temperature. Specifically, it is believed that Paracetamol inhibits a specific enzyme called cyclooxygenase (COX), particularly COX-2 in the central nervous system. However, its activity on COX enzymes outside the central nervous system is limited, which explains why Paracetamol has minimal anti-inflammatory effects compared to nonsteroidal anti-inflammatory drugs (NSAIDs).
• Mefenamic Acid, on the other hand, is a nonsteroidal anti-inflammatory drug (NSAID). It works by inhibiting both COX-1 and COX-2 enzymes throughout the body. These enzymes are responsible for the production of prostaglandins, which, as mentioned earlier, mediate pain, inflammation, and fever. By blocking COX enzymes, Mefenamic Acid reduces the synthesis of prostaglandins, thereby alleviating pain and inflammation at the site of the problem. Unlike Paracetamol, Mefenamic Acid has significant anti-inflammatory properties due to its broader inhibition of COX enzymes outside the central nervous system. This makes it particularly effective for conditions involving inflammation, such as muscle aches, joint pain, and menstrual cramps.
• When combined in ALGIDUO SYRUP, Paracetamol and Mefenamic Acid offer a dual-action approach to pain and fever management. Paracetamol primarily targets pain and fever by acting on the central nervous system, while Mefenamic Acid addresses pain, inflammation, and fever by acting on both the central nervous system and peripheral tissues. This combination can provide more comprehensive relief than either medication used alone. The synergistic effect means that lower doses of each medication may be required to achieve the desired therapeutic effect, potentially reducing the risk of side effects.
• In summary, ALGIDUO SYRUP works by leveraging the distinct yet complementary mechanisms of Paracetamol and Mefenamic Acid. Paracetamol reduces pain and fever by inhibiting prostaglandin synthesis in the brain, while Mefenamic Acid reduces pain, inflammation, and fever by inhibiting COX enzymes throughout the body. This combined action makes ALGIDUO SYRUP an effective option for managing a range of painful and febrile conditions, particularly when inflammation is a contributing factor.

ALGIDUO SYRUP 150 ML, like other medications, can cause side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, stomach upset, and abdominal pain. Some individuals may experience drowsiness or dizziness. Less common side effects could involve allergic reactions such as skin rash, itching, or swelling, as well as liver problems (indicated by jaundice - yellowing of the skin or eyes). Rarely, serious side effects like severe allergic reactions (anaphylaxis) or blood disorders may occur. If you experience any unusual or severe symptoms, discontinue use and consult your doctor immediately. This is not an exhaustive list, and it's important to read the product leaflet for more detailed information.

• If you miss a dose of Algiduo Syrup, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep ALGIDUO SYP 150ML away from the reach of children and pets.
• Store ALGIDUO SYP 150ML at room temperature.

• **Shake Well Before Use:** Always shake the Algiduo Syrup bottle well before each use to ensure that the medication is evenly distributed. This helps in providing a consistent and accurate dose for your child.
• **Administer the Correct Dosage:** Use the measuring cup or dropper provided with the syrup to administer the precise dosage as prescribed by your doctor. Avoid using household spoons, as they may not provide accurate measurements. Giving the correct dose ensures the medicine works effectively.
• **Give with or Without Food:** Algiduo Syrup can be given with or without food, as directed by your healthcare provider. If your child experiences stomach upset, try giving the syrup with a small amount of food to help reduce discomfort.
• **Storage Instructions:** Store Algiduo Syrup in a cool, dry place away from direct sunlight and heat. Keep the bottle tightly closed when not in use. Proper storage helps maintain the effectiveness of the medication. Ensure it is out of reach of children.
• **Monitor for Side Effects:** While Algiduo Syrup is generally well-tolerated, monitor your child for any potential side effects such as drowsiness, nausea, or allergic reactions. If you notice any unusual symptoms, consult your doctor immediately. Knowing potential side effects can help you react quickly if needed.

• ALGIDUO SYRUP 150 ML can be taken with or without food. However, if you experience stomach upset, taking it with food may help. Consult your doctor if you have any concerns.