AMICOLON 15 EMULSION INJECTION 5 ML

How AMICOLON 15 EMULSION INJECTION 5 ML Works

• AMICOLON 15 EMULSION INJECTION 5 ML is a specialized intravenous lipid emulsion designed to provide essential fatty acids and energy to patients who are unable to obtain adequate nutrition through oral or enteral routes. This formulation is particularly useful in situations where the digestive system is compromised or non-functional, such as in cases of severe malnutrition, short bowel syndrome, or post-operative ileus.
• The key components of AMICOLON 15 EMULSION INJECTION include soybean oil, which serves as the primary source of triglycerides. These triglycerides are broken down by the body into fatty acids, which are then used for energy production and as building blocks for cell membranes and various signaling molecules. Essential fatty acids, such as linoleic acid (omega-6) and alpha-linolenic acid (omega-3), are crucial for maintaining overall health and supporting various physiological processes, including immune function, inflammation regulation, and brain development.
• When AMICOLON 15 EMULSION INJECTION is administered intravenously, the lipid particles are directly introduced into the bloodstream. These particles are then metabolized by lipoprotein lipase, an enzyme present in the capillary endothelium of various tissues, including adipose tissue and muscle. Lipoprotein lipase hydrolyzes the triglycerides into free fatty acids and glycerol. The free fatty acids are then taken up by cells and either oxidized for energy production via beta-oxidation in the mitochondria or re-esterified into triglycerides for storage.
• The glycerol released during triglyceride hydrolysis is metabolized in the liver and can be used for gluconeogenesis, the process of synthesizing glucose from non-carbohydrate sources. This provides an additional source of energy, particularly important in patients who are unable to consume carbohydrates.
• The emulsification process of AMICOLON 15 EMULSION INJECTION is crucial for its efficient metabolism. The small particle size of the lipid emulsion ensures that it can be readily dispersed and metabolized by lipoprotein lipase. This reduces the risk of lipid accumulation in the bloodstream and minimizes potential adverse effects such as hyperlipidemia.
• Furthermore, the essential fatty acids provided by AMICOLON 15 EMULSION INJECTION play a vital role in the synthesis of eicosanoids, hormone-like substances that regulate a wide range of physiological processes, including inflammation, blood clotting, and immune responses. Adequate intake of essential fatty acids is essential for maintaining optimal health and preventing deficiency-related complications.
• In summary, AMICOLON 15 EMULSION INJECTION works by providing a readily available source of energy and essential fatty acids directly into the bloodstream. The triglycerides are broken down into fatty acids and glycerol, which are then utilized for energy production, cell membrane synthesis, and various metabolic processes. The essential fatty acids support immune function, inflammation regulation, and the synthesis of eicosanoids, contributing to overall health and well-being in patients who are unable to obtain adequate nutrition through other routes.

Like all medicines, AMICOLON 15 EMULSION INJECTION 5 ML can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Fever * Shivering * Nausea * Vomiting * Headache **Uncommon Side Effects (may affect up to 1 in 100 people):** * Allergic reactions (such as skin rash, itching, hives) * Difficulty breathing * Chest pain * Dizziness * Changes in blood pressure (high or low) * Changes in heart rate (fast or slow) * Abdominal pain * Diarrhea * Changes in liver function tests * Thrombophlebitis (inflammation of a vein with blood clot formation) at the injection site **Rare Side Effects (may affect up to 1 in 1,000 people):** * Severe allergic reaction (anaphylaxis) with symptoms such as swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, and loss of consciousness. * Fat overload syndrome (accumulation of fat in the body) * Jaundice (yellowing of the skin or eyes) * Blood disorders **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Pulmonary embolism (blood clot in the lungs) * Hypersensitivity reactions **If you experience any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed above.**

• Since this medication is administered by a healthcare professional in a clinical setting, the possibility of missing a dose is unlikely. However, if you have concerns about a missed dose, please consult with your doctor or the healthcare provider administering the medication for further guidance.

• Keep AMICOLON 15 EMULSION INJ 5ML away from the reach of children and pets.
• Store AMICOLON 15 EMULSION INJ 5ML at room temperature.

• **Always administer under strict medical supervision:** AMICOLON 15 EMULSION INJECTION 5 ML is a prescription medication and should only be administered by trained healthcare professionals in a clinical setting. This allows for immediate management of any potential adverse reactions.
• **Monitor vital signs closely:** During and after administration, vigilant monitoring of vital signs such as heart rate, blood pressure, and respiratory rate is crucial. Report any significant changes to the attending physician immediately.
• **Inform your doctor about existing allergies:** Before receiving AMICOLON 15 EMULSION INJECTION 5 ML, disclose any known allergies, particularly to lipid emulsions, eggs, soybeans, or any other medications. This information helps prevent severe allergic reactions.
• **Adhere to the prescribed dosage and infusion rate:** The dosage and infusion rate are determined by your doctor based on individual needs. Strict adherence to these guidelines is essential to ensure optimal effectiveness and minimize the risk of complications. Do not self-adjust the dose or rate.
• **Report any unusual symptoms immediately:** After receiving AMICOLON 15 EMULSION INJECTION 5 ML, promptly report any unusual symptoms such as fever, chills, skin rash, itching, difficulty breathing, nausea, vomiting, or pain at the injection site to your healthcare provider. Early reporting allows for timely intervention and management.

• There is no known interaction between AMICOLON 15 EMULSION INJECTION 5 ML and food. This medicine is administered intravenously by a healthcare professional and does not require any dietary adjustments.