GLUFORMIN XL 1000MG TABLET 15'S

How GLUFORMIN XL 1000MG TABLET 15'S Works

• GLUFORMIN XL 1000MG TABLET 15'S contains metformin, a medicine used to treat type 2 diabetes. It works primarily by addressing insulin resistance and reducing glucose production in the liver, which are two key problems in type 2 diabetes. Here’s a detailed explanation of how it works:
• 1. **Reduces Hepatic Glucose Production:** The liver is a major glucose-producing organ. In type 2 diabetes, the liver often produces excessive glucose, contributing to high blood sugar levels. Metformin decreases glucose production in the liver by inhibiting gluconeogenesis (the process of creating glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose).
• 2. **Improves Insulin Sensitivity:** Insulin resistance is a condition where the body's cells do not respond effectively to insulin. Insulin is needed for glucose to enter cells from the bloodstream, providing them with energy. Metformin enhances the sensitivity of cells to insulin, allowing them to use glucose more effectively. This helps lower blood sugar levels because more glucose is taken up by the cells.
• 3. **Slows Glucose Absorption in the Intestines:** Metformin can slightly reduce the absorption of glucose from the intestines after a meal. This action helps to prevent sharp spikes in blood sugar levels that can occur after eating. Although this effect is less pronounced than the other mechanisms, it contributes to overall blood sugar control.
• 4. **Activates AMPK:** Metformin activates an enzyme called AMP-activated protein kinase (AMPK). AMPK is a central regulator of energy metabolism in cells. Activation of AMPK leads to various beneficial effects, including increased glucose uptake, increased fatty acid oxidation, and reduced lipid synthesis. These effects collectively improve glucose and lipid metabolism.
• By reducing glucose production in the liver, improving insulin sensitivity, and slightly decreasing glucose absorption, GLUFORMIN XL 1000MG TABLET 15'S helps to lower blood sugar levels in people with type 2 diabetes. It's important to take this medication as prescribed by your doctor, usually with meals, to minimize potential side effects and maximize its effectiveness. This medication is often used in combination with lifestyle changes, such as diet and exercise, to achieve optimal blood sugar control.

Like all medicines, GLUFORMIN XL 1000MG TABLET 15'S can cause side effects, although not everybody gets them. **Very common (may affect more than 1 in 10 people):** * Nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. These side effects occur most often when starting GLUFORMIN XL 1000MG TABLET 15'S and usually disappear on their own. Taking the tablets with meals can help reduce these problems. **Common (may affect up to 1 in 10 people):** * Taste disturbance * Decreased vitamin B12 levels * Skin reactions such as redness, itching, and hives. **Very rare (may affect up to 1 in 10,000 people):** * Lactic acidosis. Symptoms include vomiting, abdominal pain, muscle cramps, a general feeling of being unwell with severe tiredness, and difficulty breathing. If this happens to you, seek immediate medical attention. * Abnormal liver function tests, hepatitis (inflammation of the liver) with or without jaundice (yellowing of the skin and whites of the eyes). * Skin reactions such as erythema multiforme (red, often target-shaped patches or blisters). **Not known (frequency cannot be estimated from the available data):** * If you experience an allergic reaction such as skin rash, itching, hives, swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, stop taking GLUFORMIN XL 1000MG TABLET 15'S and seek immediate medical attention.

• If you miss a dose of GLUFORMIN XL 1000MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep GLUFORMIN XL 1000MG TAB 1X15 away from the reach of children and pets.
• Store GLUFORMIN XL 1000MG TAB 1X15 at room temperature.

• Take GLUFORMIN XL 1000MG TABLET 15'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet. Swallow it whole with a glass of water, preferably with your evening meal. Taking it with food helps to minimize stomach upset, a common side effect.
• Consistency is key! Try to take GLUFORMIN XL 1000MG TABLET 15'S at the same time each day to maintain a steady level of medication in your body. This will help you remember to take it and maximize its effectiveness in controlling your blood sugar levels.
• GLUFORMIN XL 1000MG TABLET 15'S is most effective when combined with a healthy lifestyle. Follow a balanced diet that is low in sugars and carbohydrates, and engage in regular physical activity, such as brisk walking, jogging, or swimming, for at least 30 minutes most days of the week. A healthy lifestyle complements the medication's effects.
• Stay hydrated by drinking plenty of water throughout the day. Adequate hydration helps your kidneys function properly and reduces the risk of dehydration, which can sometimes occur with GLUFORMIN XL 1000MG TABLET 15'S. Aim for at least 8 glasses of water daily, unless otherwise advised by your doctor.
• Regularly monitor your blood sugar levels as directed by your doctor or diabetes educator. Keeping a log of your blood sugar readings will help you and your healthcare team assess how well the medication is working and make any necessary adjustments to your treatment plan. This includes checking your levels before and after meals.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shakiness, dizziness, and confusion. Although GLUFORMIN XL 1000MG TABLET 15'S is less likely to cause hypoglycemia than some other diabetes medications, it can still occur, especially if you skip meals or exercise strenuously. Carry a source of fast-acting sugar, such as glucose tablets or fruit juice, with you at all times.
• Inform all your healthcare providers, including your dentist, that you are taking GLUFORMIN XL 1000MG TABLET 15'S. This is especially important before undergoing any surgery or medical procedures that may require you to temporarily stop taking the medication.
• If you experience any persistent or bothersome side effects, such as nausea, diarrhea, or stomach pain, talk to your doctor. They may be able to adjust your dose or recommend other ways to manage the side effects. Do not stop taking the medication without consulting your doctor first.
• Store GLUFORMIN XL 1000MG TABLET 15'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage helps to maintain the medication's effectiveness.
• Attend all scheduled appointments with your doctor and other healthcare providers. Regular check-ups are essential for monitoring your diabetes and ensuring that your treatment plan is working effectively. These appointments provide an opportunity to discuss any concerns or questions you may have.

• GLUFORMIN XL 1000MG TABLET 15'S should be taken with food to help reduce stomach upset. Consistent timing with meals is recommended for optimal blood sugar control. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis, a serious side effect. Inform your doctor about your dietary habits, especially if you are on a special diet.