NIGRAIN PLUS TABLET 10'S

How NIGRAIN PLUS TABLET 10'S Works

• Nigrain Plus Tablet 10's is a combination medication designed to alleviate migraine headaches. It combines the synergistic actions of its ingredients to provide comprehensive relief from migraine symptoms. Each component plays a specific role in tackling the multifaceted nature of migraines.
• **Paracetamol:** Paracetamol, also known as acetaminophen, is a widely used analgesic (pain reliever) and antipyretic (fever reducer). In Nigrain Plus, paracetamol primarily works by inhibiting the production of prostaglandins in the brain. Prostaglandins are chemicals that contribute to inflammation and pain signaling. By reducing prostaglandin synthesis, paracetamol helps to lessen the pain associated with migraine headaches. It's particularly effective for mild to moderate migraine pain and can also help reduce any associated fever.
• **Prochlorperazine:** Prochlorperazine is an antiemetic, meaning it helps to reduce nausea and vomiting. It belongs to a class of drugs called phenothiazines, which work by blocking dopamine receptors in the brain. Dopamine is a neurotransmitter involved in various functions, including the vomiting reflex. Migraines often trigger nausea and vomiting, exacerbating the discomfort. Prochlorperazine helps to control these symptoms by preventing signals from reaching the vomiting center in the brain, thus providing relief from nausea and vomiting associated with migraines. Its inclusion in Nigrain Plus is crucial for managing the debilitating gastrointestinal symptoms that often accompany migraines.
• **Caffeine:** Caffeine is a stimulant that enhances alertness and reduces fatigue. It also has vasoconstrictive properties, meaning it can narrow blood vessels. During a migraine, blood vessels in the brain can dilate, contributing to the throbbing pain. Caffeine helps to constrict these blood vessels, reducing blood flow and alleviating the pressure that causes headache pain. Furthermore, caffeine can enhance the effectiveness of paracetamol by increasing its absorption and analgesic effects. It also combats the fatigue often associated with migraines, helping patients feel more alert and functional.
• In summary, Nigrain Plus Tablet 10's tackles migraines from multiple angles. Paracetamol reduces pain and fever by inhibiting prostaglandin synthesis. Prochlorperazine controls nausea and vomiting by blocking dopamine receptors. Caffeine constricts blood vessels, enhances paracetamol's effects, and reduces fatigue. This combination provides comprehensive relief from migraine symptoms, addressing both the pain and the associated discomforts like nausea and fatigue, allowing patients to function more effectively during a migraine attack. It is important to use this medication as directed by a healthcare professional to ensure safe and effective treatment.

Nigrain Plus Tablet may cause several side effects, although not everyone experiences them. Common side effects may include: * Nausea * Vomiting * Heartburn * Stomach pain * Drowsiness * Dizziness Less common, but potentially more serious side effects include: * Allergic reactions (rash, itching, swelling, difficulty breathing) * Liver problems (yellowing of skin/eyes, dark urine, persistent fatigue) * Kidney problems (changes in urine output, swelling in ankles/feet) * Increased blood pressure * Changes in heart rate * Headache * Restlessness * Insomnia * Anxiety * Confusion This is not an exhaustive list. If you experience any unusual symptoms while taking Nigrain Plus Tablet, consult your doctor immediately.

• If you miss a dose of Nigrain Plus Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep NIGRAIN PLUS TAB 1X10 away from the reach of children and pets.
• Store NIGRAIN PLUS TAB 1X10 at room temperature.

• Take Nigrain Plus Tablet 10'S exactly as prescribed by your doctor. Do not exceed the recommended dosage, as this can increase the risk of side effects. It's usually taken at the first sign of a migraine to provide the most effective relief.
• For optimal results, take Nigrain Plus Tablet 10'S with a full glass of water. This helps in faster absorption and distribution of the medication in your body, providing quicker relief from migraine symptoms. Avoid taking it on an empty stomach to minimize potential gastrointestinal discomfort.
• If you experience frequent migraines, maintain a migraine diary to track potential triggers such as stress, certain foods, or changes in sleep patterns. Sharing this information with your doctor can help in identifying and managing your migraine triggers effectively alongside using Nigrain Plus Tablet 10'S.
• Be aware of potential side effects such as drowsiness, dizziness, or nausea while taking Nigrain Plus Tablet 10'S. Avoid activities that require alertness, such as driving or operating heavy machinery, until you know how the medication affects you. If side effects persist or worsen, consult your doctor.
• Store Nigrain Plus Tablet 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Always check the expiration date before use and discard any expired medication properly. Do not flush the medication down the toilet or pour it into a drain unless instructed to do so.

• NIGRAIN PLUS TABLET 10'S is generally safe to take with food. However, if you experience any stomach upset or nausea, you can take it after meals. There are no specific food items that are known to interact negatively with this medication. It's always a good idea to maintain a consistent diet while taking any medication.