PREGALIN M SR 150MG TABLET 10'S

How PREGALIN M SR 150MG TABLET 10'S Works

• Pregalin M SR 150mg Tablet is a combination medication containing pregabalin and methylcobalamin. It is primarily used to manage neuropathic pain, a type of nerve pain that can occur due to various conditions such as diabetes, shingles, or injuries. Understanding how each component works can help clarify the overall mechanism of the medication.
• **Pregabalin:** Pregabalin is an anticonvulsant and analgesic. Its primary mechanism involves binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, pregabalin reduces the influx of calcium into nerve terminals. This reduction in calcium influx leads to decreased release of several neurotransmitters, including glutamate, noradrenaline, and substance P. These neurotransmitters are involved in the transmission of pain signals. By reducing their release, pregabalin helps to alleviate neuropathic pain. Essentially, it calms overactive nerves and reduces the intensity of pain signals sent to the brain.
• **Methylcobalamin:** Methylcobalamin is a form of vitamin B12. It plays a crucial role in nerve health and regeneration. In cases of neuropathic pain, nerves may be damaged or not functioning correctly. Methylcobalamin helps in the myelin sheath formation, which is a protective covering around nerve fibers. This myelin sheath ensures proper nerve signal transmission. Additionally, methylcobalamin supports nerve cell metabolism and helps repair damaged nerves. By improving nerve function and health, methylcobalamin contributes to reducing neuropathic pain and promoting nerve recovery.
• **Synergistic Effect:** The combination of pregabalin and methylcobalamin offers a synergistic effect. Pregabalin directly reduces the excitability of nerves by modulating neurotransmitter release, while methylcobalamin promotes nerve healing and improves nerve function. This dual action helps to manage neuropathic pain more effectively than either medication could alone. Patients typically experience a reduction in pain intensity, improved nerve function, and enhanced overall quality of life. Always use under medical supervision to manage and monitor any potential side effects.

Common side effects of Pregalin M SR 150mg Tablet may include: * Dizziness * Sleepiness * Headache * Blurred vision * Dry mouth * Weight gain * Difficulty concentrating * Swelling of extremities (arms, legs, hands, feet) * Uncoordinated movement Less common but potentially serious side effects include: * Severe allergic reactions (rash, itching, swelling, difficulty breathing) * Muscle pain or weakness * Changes in mood or behavior (depression, anxiety, agitation) * Suicidal thoughts * Vision changes * Memory problems * Decreased sexual desire or function * Nausea, vomiting, constipation, diarrhea * Peripheral neuropathy * Tremors This is not an exhaustive list, and it's important to consult your doctor if you experience any unusual or bothersome symptoms while taking Pregalin M SR 150mg Tablet.

• If you miss a dose of Pregalin M SR 150mg Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep PREGALIN M SR 150MG TAB 1X10 away from the reach of children and pets.
• Store PREGALIN M SR 150MG TAB 1X10 at room temperature.

• Take PREGALIN M SR 150MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. This medication is typically taken once daily, but your doctor will determine the most suitable regimen for you. Consistency is key for optimal results.
• PREGALIN M SR 150MG TABLET 10'S can be taken with or without food. If you experience stomach upset, taking it with food might help. However, maintaining a consistent routine regarding food intake alongside the medication is generally advisable.
• Be aware of potential side effects. Common side effects include dizziness, drowsiness, and blurred vision. If you experience these, avoid activities requiring alertness, such as driving or operating heavy machinery, until you know how the medication affects you. Report any severe or persistent side effects to your doctor immediately. Other possible side effects may include peripheral edema (swelling in the extremities), weight gain, and dry mouth.
• Do not abruptly stop taking PREGALIN M SR 150MG TABLET 10'S. Suddenly discontinuing the medication can lead to withdrawal symptoms. Your doctor will gradually reduce the dosage if you need to stop taking it. Adherence to the prescribed tapering schedule is essential to minimize any discomfort or potential complications.
• Inform your doctor about all other medications, supplements, and herbal products you are taking before starting PREGALIN M SR 150MG TABLET 10'S. Drug interactions can occur, potentially affecting the medication's efficacy or increasing the risk of side effects. This includes over-the-counter medications as well as prescription drugs. Special caution should be exercised with other drugs that cause sedation.
• Store PREGALIN M SR 150MG TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Ensure the packaging is tightly closed to maintain the medication's integrity. Do not store in the bathroom.
• If you miss a dose of PREGALIN M SR 150MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
• Regularly monitor your blood sugar levels, especially if you have diabetes, as PREGALIN M SR 150MG TABLET 10'S can affect blood sugar control. Report any significant changes in your blood sugar levels to your doctor. Discuss any necessary adjustments to your diabetes management plan with your healthcare provider.
• Attend all scheduled follow-up appointments with your doctor. These appointments are crucial for monitoring your progress, assessing the medication's effectiveness, and addressing any concerns or side effects you may be experiencing. Your doctor may also adjust your dosage based on your response to the treatment.
• Maintain a healthy lifestyle while taking PREGALIN M SR 150MG TABLET 10'S. This includes eating a balanced diet, engaging in regular physical activity, and getting enough sleep. A healthy lifestyle can complement the medication's effects and improve your overall well-being.

• PREGALIN M SR 150MG TABLET 10'S can be taken with or without food. Food does not significantly affect the absorption of pregabalin or methylcobalamin, the active ingredients in this medication. However, maintaining a consistent routine regarding food intake when taking this medication is advisable. This helps to ensure consistent absorption and effectiveness of the medicine.
• If you experience any stomach upset while taking this medication, taking it with food may help to reduce these effects. Always follow your doctor's instructions regarding dosage and timing.