TRIMETRIDE 2MG TABLET 10'S

How TRIMETRIDE 2MG TABLET 10'S Works

• TRIMETRIDE 2MG TABLET contains Trimetazidine which is an anti-ischemic metabolic agent. It works by optimizing the energy metabolism of cells, particularly in conditions where the oxygen supply is limited, such as in angina pectoris (chest pain caused by reduced blood flow to the heart).
• Under normal conditions, cells primarily use fatty acids and glucose for energy production. Fatty acids require more oxygen to metabolize compared to glucose. During ischemia (reduced blood flow), the oxygen supply is insufficient, leading to impaired fatty acid metabolism. This results in an accumulation of partially oxidized fatty acids, which can be detrimental to cellular function.
• Trimetazidine shifts the cell's energy metabolism from fatty acid oxidation to glucose oxidation. It inhibits the enzyme 3-ketoacyl-CoA thiolase (3-KAT), which is involved in the final step of fatty acid beta-oxidation. By inhibiting this enzyme, Trimetazidine reduces fatty acid metabolism and promotes glucose metabolism. Since glucose metabolism requires less oxygen, this helps the cells to maintain their energy production even under ischemic conditions.
• By improving energy metabolism in oxygen-deprived cells, Trimetazidine helps to maintain cellular function and viability. In the context of angina, this translates to a reduction in the frequency and severity of chest pain episodes, as the heart muscle cells are better able to function despite the reduced blood flow. It does NOT affect heart rate or blood pressure directly.
• In essence, Trimetazidine acts as a metabolic modulator, optimizing energy production at the cellular level to protect against the detrimental effects of ischemia, particularly in the heart.

Common side effects of Trimetride may include nausea, vomiting, stomach upset, headache, dizziness, and skin rash. Less common but potentially serious side effects include allergic reactions (hives, itching, swelling), liver problems (jaundice, dark urine), and changes in blood counts. Other reported side effects are diarrhoea, constipation, abdominal pain, dry mouth, fatigue, sleep disturbances, anxiety, and muscle weakness. Consult your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of Trimetride 2mg Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep TRIMETRIDE 2MG TAB 1X10 away from the reach of children and pets.
• Store TRIMETRIDE 2MG TAB 1X10 at room temperature.

• **Take TRIMETRIDE 2MG TABLET as Prescribed:** Always follow your doctor's instructions regarding dosage and timing. Do not exceed the prescribed dose or discontinue use without consulting your healthcare provider, as this can affect the effectiveness of the treatment and potentially lead to adverse effects.
• **Consistent Timing for Optimal Results:** For best results, take TRIMETRIDE 2MG TABLET at the same time each day. This helps maintain a steady level of the medication in your body, which can improve its effectiveness in managing your condition. Set a daily reminder if needed to ensure you don't miss a dose.
• **Be Mindful of Potential Side Effects:** While TRIMETRIDE 2MG TABLET is generally well-tolerated, some individuals may experience side effects. Common side effects may include nausea, headache, or dizziness. If you experience any persistent or bothersome side effects, promptly inform your doctor or pharmacist for guidance. Serious side effects are rare but require immediate medical attention.
• **Dietary Considerations:** In general, TRIMETRIDE 2MG TABLET can be taken with or without food. However, if you experience stomach upset, taking it with a meal may help reduce discomfort. Discuss any specific dietary concerns or restrictions with your doctor to ensure the medication works effectively for you. Avoid excessive alcohol consumption as it may interfere with the drug's efficacy.
• **Storage and Handling:** Store TRIMETRIDE 2MG TABLET in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Check the expiration date before use, and properly dispose of any expired medication according to local regulations. Do not store the medicine in the bathroom.

• While taking TRIMETRIDE 2MG TABLET 10'S, there are no specific food restrictions. It can be taken with or without food. However, it's always a good idea to maintain a consistent dietary pattern as advised by your doctor.