VALRATE CR 300MG TABLET 10'S

How VALRATE CR 300MG TABLET 10'S Works

• VALRATE CR 300MG TABLET 10'S contains Valproic Acid as its active ingredient. Valproic Acid is a broad-spectrum anticonvulsant and mood-stabilizing medication. It works through several mechanisms to control seizures and stabilize mood. One primary way it functions is by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain. GABA is an inhibitory neurotransmitter that reduces the excitability of neurons. By increasing GABA levels, Valproic Acid helps to calm overactive nerve cells, reducing the likelihood of seizures.
• Specifically, Valproic Acid is believed to enhance GABA's effects by inhibiting GABA transaminase, an enzyme that breaks down GABA. This inhibition results in higher levels of GABA in the synaptic cleft, the space between nerve cells. The increased GABA then binds to GABA receptors on neighboring neurons, inhibiting their firing and reducing the spread of abnormal electrical activity in the brain. This is particularly beneficial in managing various types of seizures, including generalized tonic-clonic seizures, absence seizures, and myoclonic seizures.
• In addition to its effects on GABA, Valproic Acid also affects voltage-gated sodium channels. These channels play a crucial role in the transmission of electrical signals along nerve cells. Valproic Acid can block these sodium channels, reducing the ability of neurons to fire rapidly and repetitively. By stabilizing neuronal membranes and reducing neuronal excitability, Valproic Acid helps prevent the initiation and propagation of seizures. This mechanism complements its GABA-enhancing effects to provide comprehensive seizure control.
• Furthermore, Valproic Acid influences the activity of T-type calcium channels. These channels are involved in regulating neuronal excitability, particularly in thalamic neurons, which play a key role in absence seizures. By modulating T-type calcium channel activity, Valproic Acid can help control the rhythmic, spike-and-wave discharges characteristic of absence seizures. This multi-faceted approach, affecting GABA, sodium channels, and calcium channels, contributes to the effectiveness of VALRATE CR 300MG TABLET 10'S in managing a range of seizure disorders and stabilizing mood in conditions like bipolar disorder. The 'CR' in VALRATE CR indicates 'Controlled Release,' meaning the medication is released slowly over time, providing a more stable blood concentration and reducing the frequency of dosing.
• Therefore, VALRATE CR 300MG TABLET 10'S offers sustained release of valproic acid which ensures consistent therapeutic levels, minimizes fluctuations, and enhances patient compliance. Valproic acid works in the brain by increasing the levels of GABA and reducing the excessive electrical activity. This combination of effects leads to seizure control and mood stabilization, ultimately improving the quality of life for individuals with epilepsy and bipolar disorder. Consult your healthcare professional to get a detailed overview.

Common side effects of VALRATE CR 300MG Tablet may include nausea, vomiting, stomach pain, diarrhea, constipation, loss of appetite, weight gain, tremors, headache, dizziness, drowsiness, blurred vision, double vision, hair loss, changes in menstruation, and impaired coordination. Less common but potentially serious side effects include liver problems, pancreatitis, low blood cell counts, allergic reactions (rash, itching, swelling), and changes in mood or behavior, including depression and suicidal thoughts. Seek immediate medical attention if you experience yellowing of the skin or eyes, severe abdominal pain, unusual bleeding or bruising, or any sudden changes in mood or behavior.

• If you miss a dose of Valrate CR 300mg Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep VALRATE CR 300MG TAB 1X10 away from the reach of children and pets.
• Store VALRATE CR 300MG TAB 1X10 at room temperature.

• Take VALRATE CR 300MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medicine without consulting your healthcare provider, as this can lead to serious complications, especially if you are using it to manage seizures.
• VALRATE CR 300MG TABLET 10'S is often taken with food to help reduce stomach upset. If you experience nausea or indigestion, try taking it immediately after a meal or snack to minimize these side effects. Consistent timing with meals can also improve absorption.
• Avoid alcohol consumption while taking VALRATE CR 300MG TABLET 10'S, as alcohol can increase the risk of liver damage and intensify the sedative effects of the medication. This combination can also impair your judgment and coordination.
• Inform your doctor immediately if you experience any signs of liver problems, such as yellowing of the skin or eyes (jaundice), dark urine, severe abdominal pain, or persistent nausea and vomiting. Liver function tests may be needed to monitor your condition.
• If you are a woman of childbearing age, discuss contraception options with your doctor before starting VALRATE CR 300MG TABLET 10'S. This medication can cause birth defects, so it's crucial to use effective birth control while taking it and to inform your doctor immediately if you become pregnant.
• Maintain regular follow-up appointments with your doctor while taking VALRATE CR 300MG TABLET 10'S. Routine blood tests may be necessary to monitor liver function, blood cell counts, and valproic acid levels in your body to ensure the medication is working effectively and safely.
• Be aware that VALRATE CR 300MG TABLET 10'S can sometimes cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how the medication affects you. Take extra precautions to prevent falls and injuries.
• Keep VALRATE CR 300MG TABLET 10'S out of reach of children and pets. Store the medication in a cool, dry place away from direct sunlight and moisture. Do not store it in the bathroom.
• If you are scheduled for any surgery or medical procedure, inform your doctor or dentist that you are taking VALRATE CR 300MG TABLET 10'S. This is important because valproic acid can affect blood clotting and may need to be managed before and after the procedure.
• Do not crush, chew, or break the VALRATE CR 300MG TABLET 10'S. Swallow the tablet whole with a glass of water. Altering the tablet can affect the way the medication is released into your body.

• VALRATE CR 300MG TABLET 10'S can be taken with or without food. However, it is generally recommended to take it with food to minimize stomach upset. Consistent timing with meals can also help maintain stable blood levels of the medication. Avoid excessive alcohol consumption as it may increase the risk of side effects.