XIRTAM AM TABLET 10'S

How XIRTAM AM TABLET 10'S Works

• XIRTAM AM TABLET 10'S is a combination medication designed to manage hypertension (high blood pressure). It combines two active ingredients, each working through different mechanisms to effectively lower blood pressure. These components are Amlodipine and Olmesartan.
• Amlodipine is a calcium channel blocker. Calcium channel blockers work by preventing calcium from entering the muscle cells of the heart and blood vessels. This causes the blood vessels to relax and widen, making it easier for the heart to pump blood. By reducing the resistance in blood vessels, amlodipine helps lower blood pressure. It primarily targets the vascular smooth muscle, leading to vasodilation (widening of blood vessels). This vasodilation decreases peripheral vascular resistance, which in turn reduces blood pressure. The relaxed blood vessels also improve blood flow to the heart, reducing the workload on the heart.
• Olmesartan, on the other hand, is an angiotensin II receptor blocker (ARB). Angiotensin II is a hormone that causes blood vessels to constrict, which increases blood pressure. Olmesartan blocks the action of angiotensin II by preventing it from binding to its receptors in the blood vessels. This blockage leads to vasodilation and reduces the release of aldosterone, a hormone that causes the kidneys to retain sodium and water. By blocking angiotensin II, olmesartan helps blood vessels relax and reduces the amount of sodium and water retained by the body, both of which contribute to lowering blood pressure.
• The synergistic effect of amlodipine and olmesartan provides a more comprehensive approach to managing hypertension. Amlodipine directly relaxes blood vessels, while olmesartan blocks the hormonal effects that cause blood vessel constriction and fluid retention. Together, they offer better blood pressure control than either medication alone. This combination helps to reduce the risk of cardiovascular events such as heart attack, stroke, and kidney problems associated with uncontrolled hypertension.
• Furthermore, XIRTAM AM TABLET 10'S helps to protect target organs like the heart, brain, and kidneys from damage caused by prolonged high blood pressure. By maintaining healthy blood pressure levels, it reduces the strain on these organs and minimizes the risk of complications.
• In summary, XIRTAM AM TABLET 10'S works by combining the effects of a calcium channel blocker (amlodipine) and an angiotensin II receptor blocker (olmesartan) to relax blood vessels, reduce fluid retention, and ultimately lower blood pressure, thereby protecting against cardiovascular events and target organ damage.

Like all medicines, XIRTAM AM TABLET 10'S can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Headache * Dizziness * Swelling of ankles or feet (edema) * Fatigue * Palpitations (feeling your heartbeat) * Flushing (redness of the face) * Abdominal pain * Nausea **Uncommon Side Effects (may affect up to 1 in 100 people):** * Difficulty sleeping * Mood changes, including anxiety * Tremor * Visual disturbances * Tinnitus (ringing in the ears) * Low blood pressure * Shortness of breath * Cough * Vomiting * Indigestion * Diarrhea * Constipation * Dry mouth * Increased sweating * Hair loss * Skin discoloration * Muscle cramps * Increased need to urinate, especially at night * Impotence * Breast enlargement in men * Weight gain * Joint pain **Rare Side Effects (may affect up to 1 in 1,000 people):** * Confusion **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Severe allergic reaction (anaphylaxis) * Decreased white blood cell count * Decreased platelet count * High blood sugar (hyperglycemia) * Nerve disorder that can cause weakness, tingling or numbness * Inflammation of the blood vessels * Inflammation of the stomach lining * Inflammation of the liver (hepatitis) * Yellowing of the skin or eyes (jaundice) * Increased sensitivity to sunlight **Other possible side effects:** * Serious skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis (These are very rare but require immediate medical attention.) This is not an exhaustive list. If you experience any unusual symptoms, contact your doctor or pharmacist.

• If you miss a dose of XIRTAM AM TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep XIRTAM AM TAB 1X10 away from the reach of children and pets.
• Store XIRTAM AM TAB 1X10 at room temperature.

• XIRTAM AM TABLET 10'S can be taken with or without food. However, it is important to take it at a consistent time each day to maintain a steady level of medication in your body. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medicine, as it can increase the blood levels of amlodipine, potentially leading to increased side effects.
• If you experience stomach upset, taking it with food might help.