ZOSECTA DSR CAPSULE 10'S

How ZOSECTA DSR CAPSULE 10'S Works

• ZOSECTA DSR CAPSULE 10'S is a combination medication designed to alleviate the symptoms of gastroesophageal reflux disease (GERD), such as heartburn, acid regurgitation, and epigastric pain. It contains two active ingredients: Domperidone and Pantoprazole.
• Pantoprazole, a proton pump inhibitor (PPI), works by reducing the amount of acid produced in the stomach. Parietal cells in the stomach lining are responsible for secreting hydrochloric acid, which is essential for digestion. Pantoprazole selectively binds to and inhibits the hydrogen-potassium ATPase enzyme system (also known as the proton pump) in these parietal cells. This action effectively blocks the final step in acid production, regardless of the stimulus. By decreasing gastric acid secretion, Pantoprazole helps to heal existing esophageal damage, prevent further erosion, and relieve symptoms associated with acid reflux.
• Domperidone, a prokinetic agent, enhances the motility of the gastrointestinal tract. It primarily functions by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) located in the brain, as well as in the gastrointestinal tract. The CTZ is involved in initiating nausea and vomiting. By blocking dopamine receptors in this area, Domperidone reduces nausea and vomiting. Additionally, Domperidone increases the tone and amplitude of gastric contractions, accelerates gastric emptying, and strengthens lower esophageal sphincter (LES) pressure. This coordinated action prevents acid and stomach contents from flowing back into the esophagus.
• In essence, ZOSECTA DSR CAPSULE 10'S works synergistically by reducing acid production (Pantoprazole) and promoting faster gastric emptying while preventing backflow (Domperidone). This dual action effectively manages GERD symptoms and promotes healing of the esophagus. The delayed-release formulation ensures that Pantoprazole is released in the small intestine, maximizing its absorption and effectiveness while minimizing potential degradation in the acidic environment of the stomach.

Common side effects of ZOSECTA DSR CAPSULE may include: Headache, Dizziness, Nausea, Vomiting, Stomach pain, Diarrhea, Constipation, Flatulence (gas), Dry mouth. Uncommon side effects may include: Skin rash, Itching, Weakness, Fatigue, Anxiety, Depression, Sleep disturbances, Blurred vision, Changes in liver function tests, Breast enlargement in men, Menstrual irregularities in women. Rare side effects may include: Severe allergic reactions (anaphylaxis), Blood disorders (such as decreased white blood cells or platelets), Liver problems (such as jaundice or hepatitis), Kidney problems, Muscle pain or weakness, Seizures.

• If you miss a dose of ZOSECTA DSR CAPSULE 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep ZOSECTA DSR CAP 1X10 away from the reach of children and pets.
• Store ZOSECTA DSR CAP 1X10 at room temperature.

• Take ZOSECTA DSR CAPSULE 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. It is typically taken once daily, preferably in the morning, before a meal.
• For optimal results, swallow the capsule whole with a glass of water. Do not crush, chew, or break the capsule, as this can affect the medication's release and effectiveness. This ensures the modified-release mechanism works properly, delivering the drug over an extended period.
• ZOSECTA DSR CAPSULE 10'S is designed to reduce stomach acid production and relieve symptoms of acid reflux and peptic ulcers. It may take a few days or weeks to experience the full benefits. Continue taking the medication as directed, even if you start feeling better.
• Be aware of potential side effects, such as nausea, vomiting, abdominal pain, diarrhea, and flatulence. If these side effects persist or worsen, inform your doctor. Serious side effects are rare, but seek immediate medical attention if you experience severe abdominal pain, bloody stools, or signs of an allergic reaction.
• Inform your doctor about all other medications, supplements, and herbal products you are taking, especially anticoagulants (blood thinners), antifungals (e.g., ketoconazole), and digoxin. ZOSECTA DSR CAPSULE 10'S can interact with these medications, potentially affecting their effectiveness or increasing the risk of side effects. Also, let your doctor know if you have liver or kidney problems before starting this medication. If you are pregnant or breastfeeding, discuss the risks and benefits with your healthcare provider before using ZOSECTA DSR CAPSULE 10'S.
• Lifestyle modifications can enhance the effectiveness of ZOSECTA DSR CAPSULE 10'S. Consider elevating the head of your bed, avoiding late-night meals, and refraining from smoking and alcohol consumption. These changes can help reduce acid reflux symptoms and improve overall digestive health. Also, identify and avoid trigger foods that exacerbate your symptoms, such as spicy, fatty, or acidic foods.
• Store ZOSECTA DSR CAPSULE 10'S at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication if the expiry date has passed. Dispose of unused medication properly according to local regulations. Consult your pharmacist for guidance on proper disposal methods.

• ZOSECTA DSR CAPSULE 10'S should be taken on an empty stomach, preferably 30 minutes before meals. Food can decrease the absorption of the medicine, reducing its effectiveness. Avoid fatty or heavy meals while taking this medication.
• Taking it before food helps in better absorption and quicker relief from acidity and heartburn.