ACELOFLAM MR TABLET 10'S

How ACELOFLAM MR TABLET 10'S Works

• ACELOFLAM MR Tablet is a combination medicine designed to alleviate pain and inflammation, while also relaxing muscles. It achieves this through the synergistic action of its three active ingredients: Aceclofenac, Paracetamol, and Chlorzoxazone.
• Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the production of certain chemical messengers in the body, specifically cyclooxygenase (COX) enzymes, which are responsible for causing pain and inflammation. By inhibiting COX enzymes, Aceclofenac reduces the synthesis of prostaglandins, substances that contribute to pain, swelling, and redness at the site of inflammation. This action helps to relieve pain and reduce inflammation in conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
• Paracetamol, also known as Acetaminophen, is an analgesic and antipyretic. Its mechanism of action is not fully understood, but it is believed to work primarily in the central nervous system (brain and spinal cord). Paracetamol is thought to inhibit prostaglandin synthesis in the brain, which reduces pain and fever. It elevates the pain threshold, meaning that it takes more stimulation to feel pain. Unlike NSAIDs, Paracetamol has minimal anti-inflammatory effects.
• Chlorzoxazone is a muscle relaxant. It works by acting on the central nervous system to relieve muscle spasms and stiffness. While the exact mechanism is not completely clear, it is believed to depress reflexes within the spinal cord and subcortical areas of the brain. This helps to reduce muscle tone and relieve muscle spasms, resulting in improved mobility and pain relief. Chlorzoxazone is particularly useful in treating muscle spasms associated with acute musculoskeletal conditions.
• In combination, these three ingredients provide comprehensive relief from pain, inflammation, and muscle spasms. Aceclofenac addresses inflammation and pain at the source, Paracetamol elevates the pain threshold, and Chlorzoxazone relaxes muscles, leading to a synergistic effect that is greater than the sum of their individual effects. This makes ACELOFLAM MR Tablet effective for a wide range of conditions involving musculoskeletal pain and inflammation.

Common side effects of Acecloflam MR Tablet may include nausea, vomiting, stomach pain, heartburn, diarrhea, constipation, loss of appetite, dizziness, drowsiness, headache, and skin rash or itching. Less common but more serious side effects could include stomach ulcers or bleeding, allergic reactions (such as swelling of the face, lips, or tongue, difficulty breathing), liver problems (indicated by yellowing of the skin or eyes), kidney problems (indicated by changes in urine output), increased blood pressure, and heart problems. Muscle weakness, blurred vision, and ringing in the ears are also possible. This is not an exhaustive list, and it's crucial to consult a doctor if you experience any unusual or severe symptoms while taking this medication.

• If you miss a dose of Acecloflam MR Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep ACELOFLAM MR TAB 1X10 away from the reach of children and pets.
• Store ACELOFLAM MR TAB 1X10 at room temperature.

• **Take ACELOFLAM MR as Prescribed:** Always follow your doctor's instructions regarding dosage and frequency. Do not exceed the recommended dose, even if you feel your pain is severe. It is crucial for avoiding potential side effects and ensuring the medication works effectively.
• **Swallow Whole with Water:** ACELOFLAM MR tablets should be swallowed whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system. Taking it with water helps in faster absorption.
• **Take with or After Food:** To minimize the risk of stomach upset, take ACELOFLAM MR with or immediately after a meal. This helps to protect the stomach lining from irritation caused by the medication's components. If you experience persistent stomach discomfort, consult your doctor.
• **Avoid Alcohol:** Alcohol can increase the risk of stomach bleeding and other side effects when taken with ACELOFLAM MR. It's best to avoid alcoholic beverages while you're on this medication to protect your health and maximize the benefits of the treatment. Also avoid taking any other NSAIDs (like ibuprofen) while on Aceclofenac
• **Inform Your Doctor About Other Medications:** Before starting ACELOFLAM MR, tell your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. This is important to prevent potential drug interactions that could reduce the effectiveness of ACELOFLAM MR or increase the risk of side effects. Special caution should be taken with blood thinners, diuretics and certain antidepressants.
• **Be Aware of Potential Side Effects:** While ACELOFLAM MR is generally well-tolerated, be aware of potential side effects such as nausea, vomiting, stomach pain, heartburn, diarrhea, and dizziness. If you experience any severe or persistent side effects, stop taking the medication and contact your doctor immediately. Also, watch out for allergic reactions like skin rash, itching, or swelling.
• **Store Properly:** Store ACELOFLAM MR tablets at room temperature, away from direct sunlight, heat, and moisture. Keep them out of reach of children and pets. Proper storage ensures the medication remains effective and safe to use until its expiration date.

• ACELOFLAM MR TABLET 10'S can be taken with or without food. However, if you experience stomach upset, it is advisable to take it with food or milk. Consult your doctor for further guidance.