ACEMIZ MR TABLET 10'S

How ACEMIZ MR TABLET 10'S Works

• ACEMIZ MR TABLET 10'S is a combination medicine designed to alleviate pain and muscle spasms. It contains three active ingredients: Aceclofenac, Paracetamol, and Tizanidine. Each component contributes uniquely to the overall therapeutic effect.
• Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins. Prostaglandins are chemicals in the body that contribute to pain, inflammation, and fever. By blocking their synthesis, Aceclofenac reduces pain and inflammation at the site of injury or inflammation.
• Paracetamol, also known as Acetaminophen, is an analgesic and antipyretic. It works through a different mechanism than Aceclofenac. While the exact mechanism is not fully understood, it is believed that Paracetamol primarily acts in the central nervous system to reduce pain and fever. It may inhibit prostaglandin synthesis in the brain, but its anti-inflammatory effects are minimal compared to NSAIDs like Aceclofenac.
• Tizanidine is a muscle relaxant that works by acting on the central nervous system. It is an alpha-2 adrenergic agonist, which means it binds to alpha-2 adrenergic receptors in the brain and spinal cord. This action reduces the release of excitatory neurotransmitters, which in turn decreases muscle tone and relieves muscle spasms. Tizanidine helps to relax tight, contracted muscles, providing relief from stiffness and pain associated with muscle spasms.
• The combined action of these three ingredients makes ACEMIZ MR TABLET 10'S effective in treating conditions involving pain, inflammation, and muscle spasms. Aceclofenac and Paracetamol work synergistically to reduce pain and inflammation, while Tizanidine helps to relax the muscles, breaking the cycle of pain and spasm. This combination can be particularly useful in conditions like back pain, neck pain, and other musculoskeletal disorders.
• In summary, Aceclofenac reduces pain and inflammation by blocking prostaglandin production. Paracetamol alleviates pain and fever through central nervous system mechanisms. Tizanidine relaxes muscles by acting on alpha-2 adrenergic receptors in the brain and spinal cord. Together, these ingredients provide comprehensive relief from pain, inflammation, and muscle spasms, improving overall comfort and mobility for the patient.

Like all medicines, Acemiz MR Tablet can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Nausea * Vomiting * Stomach pain * Heartburn * Diarrhea * Dizziness * Drowsiness **Uncommon Side Effects (may affect up to 1 in 100 people):** * Headache * Skin rash, itching * Constipation * Gas * Mouth ulcers * Fatigue * Anxiety * Sweating * Increased liver enzymes **Rare Side Effects (may affect up to 1 in 1,000 people):** * Serious allergic reactions (anaphylaxis) with symptoms like swelling of the face, lips, tongue, or throat, difficulty breathing, and skin rash. * Stomach ulcers or bleeding * Liver problems (hepatitis, jaundice) * Kidney problems * High blood pressure * Visual disturbances **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) with symptoms like blistering and peeling of the skin. * Blood disorders (anemia, leukopenia, thrombocytopenia) causing fatigue, easy bruising, and increased risk of infection. **If you experience any of these side effects, especially serious allergic reactions or signs of stomach bleeding, stop taking Acemiz MR Tablet and seek immediate medical attention.**

• If you miss a dose of Acemiz MR Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep ACEMIZ MR TAB 1X10 away from the reach of children and pets.
• Store ACEMIZ MR TAB 1X10 at room temperature.

• Take ACEMIZ MR TABLET 10'S exactly as prescribed by your doctor. Do not exceed the recommended dosage or duration, as it may increase the risk of side effects. It is typically prescribed to relieve pain and inflammation associated with muscle spasms.
• ACEMIZ MR TABLET 10'S can be taken with or without food, but it is generally recommended to take it after meals to minimize the risk of stomach upset. If you experience persistent stomach irritation, consult your doctor.
• Avoid alcohol consumption while taking ACEMIZ MR TABLET 10'S, as it can increase the risk of liver damage and other side effects. Alcohol can also worsen drowsiness and dizziness caused by the medication.
• Inform your doctor about all other medications, supplements, or herbal products you are currently taking before starting ACEMIZ MR TABLET 10'S. Certain medications can interact with it, potentially leading to adverse effects. Especially mention if you are taking blood thinners or other NSAIDs.
• If you experience any unusual side effects such as severe allergic reactions (rash, itching, swelling), chest pain, difficulty breathing, or signs of liver problems (yellowing of skin/eyes, dark urine), stop taking ACEMIZ MR TABLET 10'S and seek immediate medical attention. Store this medication in a cool, dry place away from direct sunlight and out of reach of children.

• While taking ACEMIZ MR TABLET 10'S, be mindful of your diet. There are no specific food items known to directly interact negatively with this medication. However, it is generally advisable to avoid consuming large amounts of alcohol while taking ACEMIZ MR TABLET 10'S, as it may increase the risk of liver problems or exacerbate side effects like drowsiness. Maintain a balanced diet and stay hydrated unless otherwise directed by your healthcare provider.