ACITROM 1MG TABLET 30'S

How ACITROM 1MG TABLET 30'S Works

• ACITROM 1MG TABLET 30'S contains Acitretin, a retinoid medication, which is a derivative of Vitamin A. It is primarily used to treat severe psoriasis and other skin disorders characterized by abnormal keratinization (the process by which skin cells mature and harden). Acitretin works by influencing the growth and development of skin cells, helping to normalize the process of keratinization, and reducing inflammation.
• The exact mechanism by which Acitretin exerts its therapeutic effects is complex and not fully understood. However, it is believed to involve the following key processes: Binding to Retinoid Receptors: Acitretin binds to specific retinoid receptors (RARs and RXRs) located in the cell nucleus. These receptors regulate the expression of genes involved in cell growth, differentiation, and inflammation. By binding to these receptors, Acitretin can modulate gene expression and alter cellular behavior.
• Inhibition of Keratinocyte Proliferation: In skin disorders like psoriasis, keratinocytes (skin cells) proliferate excessively, leading to the formation of thick, scaly plaques. Acitretin helps to slow down the rate of keratinocyte proliferation, reducing the thickness and scaling of psoriatic lesions.
• Promotion of Keratinocyte Differentiation: Acitretin promotes the normal differentiation of keratinocytes. This means that it encourages skin cells to mature properly and undergo the normal process of keratinization, preventing the formation of abnormal, immature cells that contribute to skin problems.
• Reduction of Inflammation: Acitretin has anti-inflammatory properties. It can reduce the production of inflammatory mediators in the skin, such as cytokines and chemokines. This helps to alleviate the redness, swelling, and itching associated with inflammatory skin conditions.
• Overall, ACITROM 1MG TABLET 30'S works by targeting the underlying cellular processes that contribute to skin disorders like psoriasis. By normalizing keratinization, reducing inflammation, and modulating cell growth, it helps to improve the appearance and symptoms of affected skin. It is important to use this medication under the strict supervision of a healthcare professional, as it can have significant side effects and requires careful monitoring.

Common side effects of Acitrom 1mg Tablet may include: Increased risk of bleeding, including nosebleeds, bleeding gums, heavier menstrual periods, and easy bruising. Other possible side effects are: Gastrointestinal issues such as nausea, vomiting, diarrhea, or abdominal pain. Skin reactions like rash or itching. Hair loss. Fatigue. Dizziness. Headache. Changes in liver function tests. Rarely, Acitrom can cause serious side effects. These include: Severe bleeding or hemorrhage. Skin necrosis (death of skin tissue). Purple discoloration of the toes (purple toe syndrome). Allergic reactions. It is important to contact your doctor immediately if you experience any unusual or severe symptoms while taking Acitrom.

• If you forget to take a dose of Acitrom 1mg Tablet, take it as soon as you remember, unless it is nearly time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

• Keep ACITROM 1MG TAB 1X30 away from the reach of children and pets.
• Store ACITROM 1MG TAB 1X30 at room temperature.

• Take ACITROM 1MG TABLET 30'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. Consistency is key to effective treatment and minimizing potential complications. Adhering to your doctor's instructions ensures the medication works optimally for your specific condition. Remember, individual responses to medications vary, and your doctor has tailored the prescription to your needs.
• Monitor your INR (International Normalized Ratio) regularly as advised by your healthcare provider. ACITROM affects blood clotting, and regular INR monitoring is crucial to ensure the medication is working within the desired therapeutic range. This helps prevent both excessive bleeding and the formation of dangerous blood clots. Keep all scheduled appointments for INR testing and promptly report any changes in your health or other medications you are taking.
• Be mindful of your diet, especially your intake of Vitamin K-rich foods like leafy green vegetables (spinach, kale, broccoli). Vitamin K can interfere with the effectiveness of ACITROM. While you don't need to eliminate these foods entirely, maintaining a consistent level of intake is important. Sudden changes in your consumption of Vitamin K-rich foods can significantly affect your INR levels and require dosage adjustments. Consult your doctor or a registered dietitian for guidance on managing your diet while on ACITROM.
• Inform all your healthcare providers, including your dentist, that you are taking ACITROM before any procedures or treatments. Because ACITROM affects blood clotting, it's crucial that your healthcare team is aware of your medication status to minimize the risk of excessive bleeding during or after procedures. This includes minor procedures such as dental work or even routine injections. This allows them to take necessary precautions.
• Report any signs of unusual bleeding or bruising to your doctor immediately. These can be symptoms of ACITROM working too strongly. Signs to watch for include nosebleeds, bleeding gums, blood in your urine or stool, heavy menstrual bleeding, unexplained bruising, or prolonged bleeding from cuts. Promptly reporting these symptoms allows for timely adjustments to your medication and prevents potential complications.

• ACITROM 1MG TABLET 30'S may be taken with or without food. However, it is important to maintain a consistent dietary intake of Vitamin K-rich foods (e.g., green leafy vegetables like spinach, kale, broccoli) as significant changes in Vitamin K intake can affect the drug's efficacy. Consult your doctor or a dietician for personalized guidance on managing your Vitamin K intake while on ACITROM.