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Composition
Content Reviewed By:
Dr. Sanjay Mehta
, (MBBS)
Written By:
Ms. Kavita Desai
, (B.Pharm)
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

General precautions and other conditions
Use under medical supervisionAcotop ER 300 is intended for the treatment of functional dyspepsia after exclusion of structural or serious organic disease; it should be used only under medical supervision.
ACOTOP ER 300MG TABLET 10'S is used in the treatment of functional dyspepsia. It helps to relieve the symptoms like bloating after a meal, pain/discomfort in the upper abdomen and early satiety (feeling of fullness in a short span of time after having only little food).
ACOTOP ER 300MG TABLET 10'S should be taken before meals. Always complete the prescribed course of treatment as advised by your doctor even if you start to feel better.
ACOTOP ER 300MG TABLET 10'S is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using ACOTOP ER 300MG TABLET 10'S too early, the symptoms may return or worsen.
No, do not stop taking ACOTOP ER 300MG TABLET 10'S without consulting your doctor even if you are feeling better. Your symptoms may improve before the condition is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration.
ACOTOP ER 300MG TABLET 10'S is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
No, functional dyspepsia cannot be cured completely. But, the symptoms of functional dyspepsia such as bloating after a meal, pain/discomfort in the upper abdomen and early satiety (feeling of fullness in a short span of time after having only little food), can be effectively managed with medicines as well as a few lifestyle changes. Practise yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also reduces your stress and hence helps in keeping your symptoms well-controlled. Try to eat smaller, frequent meals and avoid eating late at night. There should be a gap of at least 3 to 4 hours between dinner and going to bed at night. Take more fiber-rich foods such as fresh fruits, vegetables and avoid spicy or oily foods. Reducing weight can also help if you are obese. These simple life-hacks can help you manage your condition a lot.
Acotop ER 300 is an extended‑release tablet containing acotiamide 300 mg, a prokinetic medicine used mainly for the treatment of functional dyspepsia, especially the postprandial distress subtype. It helps relieve symptoms such as early satiety, post‑meal fullness, upper abdominal discomfort, and bloating when no structural cause is found on routine tests. It is prescribed by a physician after appropriate evaluation and is not intended for self‑diagnosis or self‑treatment.
Acotop ER 300 contains acotiamide, which enhances gastrointestinal motility by inhibiting acetylcholinesterase in the enteric nervous system. This increases acetylcholine levels at neuromuscular junctions in the gut, improving gastric contractions and facilitating gastric emptying. It also improves gastric accommodation after meals, which can reduce post‑meal fullness and early satiety. These combined effects help alleviate symptoms of functional dyspepsia in suitable patients.
Acotop ER 300 should be taken exactly as prescribed by your doctor. The tablet should be swallowed whole with water and should not be crushed, broken, or chewed, as this can interfere with the extended‑release properties. Your doctor will decide the timing in relation to meals and the duration of therapy based on your condition and response. Do not change the dose, frequency, or duration on your own, and do not share your medicine with others.
Common side effects reported with acotiamide include headache, diarrhea, abdominal pain or discomfort, nausea, and sometimes mild elevation of liver enzymes on blood tests. These effects are usually mild and transient. If you experience persistent diarrhea, severe abdominal pain, yellowing of the skin or eyes, dark urine, or any other unusual symptoms, contact your doctor promptly. Do not stop the medicine abruptly without medical advice unless you suspect a serious reaction.
Caution is advised when using Acotop ER 300 in patients with liver or kidney impairment. Mild dysfunction may not require adjustment, but data are limited, and your doctor will decide whether the medicine is appropriate for you. In moderate to severe hepatic or renal impairment, closer monitoring or avoidance may be recommended. Inform your doctor if you have a history of hepatitis, cirrhosis, chronic kidney disease, or abnormal liver or kidney tests before starting treatment.
There is limited human data on the use of acotiamide during pregnancy. Animal studies do not always predict human risk, and the medicine should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus. If you are pregnant, think you may be pregnant, or are planning to conceive, discuss this with your doctor before starting Acotop ER 300. Do not start or continue the medicine in pregnancy without explicit medical advice.
Information on the excretion of acotiamide into human breast milk is limited. Because the potential risk to a breastfed infant is not fully known, Acotop ER 300 should be used with caution in breastfeeding women. Your doctor will weigh the benefits of treatment for you against any possible risk to the infant and may advise either close monitoring, temporary interruption of breastfeeding, or choosing an alternative therapy. Do not make changes without consulting your healthcare provider.
Acotiamide has the potential to interact with other medicines that affect gastrointestinal motility or are absorbed in a time‑dependent manner. Although major drug–drug interactions are not widely reported, caution is advisable when it is combined with anticholinergic agents, other prokinetics, or medicines with a narrow therapeutic index. Always inform your doctor and pharmacist about all prescription drugs, over‑the‑counter products, and herbal supplements you are taking so they can assess potential interactions and adjust therapy if needed.
Alcohol can irritate the gastrointestinal tract and may worsen symptoms of functional dyspepsia, potentially reducing the benefit of Acotop ER 300. In addition, both alcohol and acotiamide may affect liver function, so concurrent use could increase the risk of liver‑related adverse effects in susceptible individuals. It is generally advisable to limit or avoid alcohol while on this medication. Discuss your alcohol intake with your doctor for individualized guidance.
If you miss a dose of Acotop ER 300, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time or extra doses to make up for a missed one, as this may increase the risk of side effects without improving efficacy. If you frequently forget doses, speak with your healthcare provider about strategies to improve adherence.
Acotop ER 300 should not be used by individuals with a known hypersensitivity or allergy to acotiamide or any component of the tablet. It is generally not appropriate for patients with mechanical gastrointestinal obstruction, severe active gastrointestinal bleeding, or suspected surgical abdomen, where prokinetic stimulation could be harmful. Use in severe liver or kidney impairment, in children, and in pregnant or breastfeeding women requires particular caution and should only occur under specialist supervision. Always undergo proper medical evaluation before starting this medicine.
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HETERO DRUGS LIMITED
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India

MRP
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₹238.26
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