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ACTEMRA 400MG/20ML INJECTION
By CIPLA PHARMACEUTICAL COMPANY LIMITED
MRP
₹
40845
₹37600
7.94 % OFF
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Composition
Product Details
About ACTEMRA 400MG/20ML INJECTION
- ACTEMRA 400MG/20ML INJECTION contains tocilizumab, a monoclonal antibody (a protein made from specific immune cells). It treats moderate to severe rheumatoid arthritis (RA) in adults who haven't responded well to other RA medications. It is also used to treat giant cell arteritis (inflammation of arteries), and several types of juvenile idiopathic arthritis (JIA) in children.
- ACTEMRA 400MG/20ML INJECTION is used for specific types of JIA, including systemic JIA (sJIA) in children aged 2 and older, and polyarticular JIA (pJIA) in children aged 1 and older. These conditions cause pain and swelling in one or more joints. Giant cell arteritis (GCA) is a condition causing inflammation of the arteries, most commonly affecting those in the head, especially the temples. Symptoms may include headaches, jaw pain, and vision changes. ACTEMRA 400MG/20ML INJECTION helps reduce inflammation and control symptoms associated with these conditions.
- Before receiving ACTEMRA , inform your doctor about any allergies, infections (current or recent), tuberculosis, intestinal problems like ulcers or diverticulitis, liver disease, cancer, kidney problems, or persistent headaches. Children with allergies to any ingredients in ACTEMRA 400MG/20ML INJECTION or severe infections should not receive this medication without consulting a doctor. If you experience any allergic reactions like difficulty breathing, chest tightness, rash, itching, hives, or swelling of the lips, tongue, or face, seek immediate medical attention. Also, inform your doctor if the child has a history of macrophage activation syndrome (MAS), a serious complication of some inflammatory diseases.
- Elderly individuals are more susceptible to infections, so caution is advised when using ACTEMRA 400MG/20ML INJECTION in this population. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Your doctor will assess the benefits and risks of using ACTEMRA 400MG/20ML INJECTION during these periods.
Uses of ACTEMRA 400MG/20ML INJECTION
- Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes inflammation of the joints.
- Giant cell arteritis (GCA), also known as temporal arteritis, is a condition in which the arteries in the head, neck, and arms become inflamed.
- Polyarticular Juvenile Idiopathic Arthritis (pJIA) is a type of arthritis that affects children under the age of 16 and causes pain, swelling, and stiffness in five or more joints in the body.
- Systemic Juvenile Idiopathic Arthritis (sJIA) is a rare form of arthritis that affects children under the age of 16. It causes whole-body inflammation, fever, and rash. ACTEMRA 400MG/20ML INJECTION can be used to treat sJIA.
- Cytokine release syndrome (CRS) is a serious immune reaction that can occur after certain types of immunotherapy. ACTEMRA 400MG/20ML INJECTION can be used to treat CRS.
Side Effects of ACTEMRA 400MG/20ML INJECTION
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
- Allergic reaction (difficulty with breathing, chest tightness, rash, itching, hives, swelling in the lips, tongue, or face)
- Fever and chills
- Mouth or skin blisters
- Stomach ache
- Upper respiratory tract infections (cough, blocked nose, runny nose, sore throat and headache)
- High blood fat (cholesterol) levels
- Injection site reactions
- Lung infection (pneumonia)
- Shingles (herpes zoster)
- Cold sores (oral herpes simplex), blisters
- Eye infection (conjunctivitis)
- Headache, dizziness, high blood pressure
- Mouth ulceration, stomach pain
- Fluid retention (edema) in the lower legs, weight increase
- Cough, shortness of breath
- Low white blood cell counts (neutropenia, leucopenia)
- Abnormal liver function tests (increased transaminases)
- Increased bilirubin shown by blood tests
- Low fibrinogen levels in the blood (a protein involved in blood clotting)
Safety Advice for ACTEMRA 400MG/20ML INJECTION
Alcohol
Consult a DoctorIt is unknown whether ACTEMRA 400MG/20ML INJECTION is safe to consume alcohol under medication. So, it is recommended to consult your doctor before taking medicine.
BreastFeeding
Consult a DoctorIt is unknown whether ACTEMRA 400MG/20ML INJECTION is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Consult your doctor for more information.
Driving
Consult a DoctorACTEMRA 400MG/20ML INJECTION may cause drowsiness in the patient while under medication. So, it is recommended to consult your doctor before handling vehicles and machinery.
Liver Function
Consult a DoctorInform your physician about any underlying liver disorders before taking ACTEMRA 400MG/20ML INJECTION, as this medication should be used cautiously in liver disease patients.
Lungs
Consult a DoctorIt is unknown whether ACTEMRA 400MG/20ML INJECTION is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Pregnancy
Consult a DoctorConsult your healthcare provider if you plan to get pregnant. However, ACTEMRA 400MG/20ML INJECTION has not been given to expectant mothers, and it should only be used when the projected advantages outweigh any possible hazards to the fetus.
Dosage of ACTEMRA 400MG/20ML INJECTION
- ACTEMRA 400MG/20ML INJECTION is administered by a healthcare professional in a hospital. It's given intravenously (through a vein). Your doctor determines the right dose, how often you receive it, and the method of administration based on your specific condition and other relevant factors. This medication is typically not self-administered and requires the supervision of trained medical personnel. The intravenous infusion usually takes about an hour to complete.
- The frequency of your ACTEMRA 400MG/20ML INJECTION infusions will depend on the condition being treated. Some conditions may require weekly infusions, while others might need them every few weeks or even months. Your doctor will monitor your response to the treatment and adjust the dosage and frequency as needed. It's crucial to keep all your scheduled appointments to ensure the medication's effectiveness.
- It's important to discuss any potential side effects or concerns with your doctor. Common side effects can include headache, upper respiratory tract infection, and increased blood pressure. More serious side effects are rare but possible, so maintaining open communication with your healthcare provider is essential throughout your treatment with ACTEMRA.
How to store ACTEMRA 400MG/20ML INJECTION?
- Keep ACTEMRA 400MG/20ML INJECTION away from the reach of children and pets.
- Store ACTEMRA 400MG/20ML INJECTION in a refrigerator (2 - 8°C). Do not freeze.
Benefits of ACTEMRA 400MG/20ML INJECTION
- ACTEMRA 400MG/20ML INJECTION works by targeting and neutralizing a specific protein in your body called interleukin-6 (IL-6). IL-6 plays a key role in triggering and amplifying inflammation. By blocking the action of IL-6, ACTEMRA 400MG/20ML INJECTION helps to reduce inflammation associated with certain conditions like rheumatoid arthritis, giant cell arteritis, and cytokine release syndrome.
- Elevated levels of IL-6 are linked to various inflammatory diseases. When your immune system overreacts, it releases excessive amounts of IL-6, leading to painful swelling, stiffness, and joint damage. ACTEMRA 400MG/20ML INJECTION helps interrupt this inflammatory cascade, providing relief from symptoms and slowing the progression of the disease.
- In conditions like cytokine release syndrome (CRS), a severe inflammatory response that can occur with certain cancer treatments, ACTEMRA 400MG/20ML INJECTION can help manage the excessive release of IL-6, thus mitigating the potentially life-threatening complications of CRS. This makes ACTEMRA 400MG/20ML INJECTION an important therapeutic option for managing this serious side effect.
How to use ACTEMRA 400MG/20ML INJECTION
- ACTEMRA 400MG/20ML INJECTION is a prescription medication administered by a healthcare professional in a hospital or clinical setting. It's crucial to not self-administer this medicine.
- The injection is typically given intravenously (directly into a vein), and the procedure is performed by a trained healthcare provider. The infusion process usually takes about an hour.
- Your doctor will determine the appropriate dosage, frequency of administration, and duration of treatment based on your specific condition, its severity, and your response to the medication. Factors such as your age, weight, other medical conditions, and current medications might also influence the prescribed dosage and treatment plan.
- During the infusion, you'll be closely monitored by medical staff for any adverse reactions or complications. After the infusion, you may be required to stay at the facility for a short observation period.
- It's essential to communicate openly with your doctor about any questions or concerns you have regarding ACTEMRA 400MG/20ML INJECTION treatment. Inform them about any other medications you are currently taking, including over-the-counter drugs and supplements, as these could potentially interact with ACTEMRA.
- Follow your doctor's instructions carefully and do not discontinue the treatment without consulting them first, even if you start to feel better. Sudden discontinuation could potentially exacerbate your condition.
FAQs
What precautions should I take while on ACTEMRA 400MG/20ML INJECTION?
Be aware of any potential infections that could come up, and consult your doctor. Your doctor will advise you to check the blood test to check. Let them know if you're having any new or worse symptoms immediately.
Can I drive when I take ACTEMRA 400MG/20ML INJECTION?
It is recommended to avoid driving when you take the medicine, as it can cause drowsiness. Consult your doctor before driving.
Can an elderly individual safely take ACTEMRA 400MG/20ML INJECTION?
The elderly are more likely to develop infections than the general population, so it is important to be cautious and consult your doctor before taking the medicine.
Can I take a vaccination while under ACTEMRA 400MG/20ML INJECTION?
Talk to your doctor if you have recently been vaccinated or are planning a vaccination because a certain vaccination (Live vaccine) should not be given while taking tocilizumab medicine.
What is the purpose of ACTEMRA 400MG/20ML INJECTION in children?
It is used to treat children with systemic juvenile idiopathic arthritis (sJIA) and polyarticular juvenile idiopathic arthritis (pJIA), which result in the pain and swelling in one or more joints in children of 1 to 2 years and above.
Does ACTEMRA 400MG/20ML INJECTION interact with other drugs?
Consult your doctor or pharmacist for more information about this.
What is the advice regarding vaccination while taking ACTEMRA 400MG/20ML INJECTION?
Talk to your doctor if you have recently been vaccinated or are planning a vaccination because certain vaccinations (Live vaccines) should not be given while taking ACTEMRA 400MG/20ML INJECTION. Your doctor may advise you to have your blood checked before giving you the medicine if you have low white blood cells, platelets, or elevated liver enzymes.
Which molecule/combination is used to make ACTEMRA 400MG/20ML INJECTION?
TOCILIZUMAB is used to make ACTEMRA 400MG/20ML INJECTION.
Is ACTEMRA 400MG/20ML INJECTION prescribed for Arthritis?
Yes, ACTEMRA 400MG/20ML INJECTION is prescribed for treating certain types of Arthritis.
Is ACTEMRA 400MG/20ML INJECTION prescribed for Osteoporosis?
ACTEMRA is not prescribed for treating Osteoporosis. It is primarily prescribed for treating certain types of Arthritis.
References
Ratings & Review
Good for generic medicine, quality medicine with affordable rate
nitesh vekariya
•
Reviewed on 03-02-2024
(5/5)
Good services, rates are competitive!
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Reviewed on 16-01-2024
(5/5)
Best medicines at best prices, thanks medkart
Ajay Varghese
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Reviewed on 05-08-2023
(5/5)
Medkart is very good for generic medicines
DD Sanghavi
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Reviewed on 14-07-2023
(3/5)
Good. Provides medicines at reasonable rates.
Jiji Varughese
•
Reviewed on 08-02-2024
(4/5)
Marketer / Manufacturer Details
CIPLA PHARMACEUTICAL COMPANY LIMITED
Country of Origin -
India
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