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ACTILYSE 20MG INJECTION
ACTILYSE 20MG INJECTION
By BOEHRINGER INGELHEIM INDIA PVT LTD
MRP
₹
23615
₹23615
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Composition
Product Details
About ACTILYSE 20MG INJECTION
- ACTILYSE 20MG INJECTION contains Alteplase, also known as recombinant tissue plasminogen activator (rt-PA). This medicine is a powerful tool used in certain urgent medical situations caused by blood clots. Think of it as a "clot buster." Its main job is to help dissolve dangerous blood clots that can block blood flow in your body.
- It is most commonly used to treat an acute ischemic stroke. This type of stroke happens when a blood clot blocks an artery supplying blood to the brain. Without blood flow, brain cells start to die rapidly. ACTILYSE 20MG INJECTION is given quickly after stroke symptoms begin, typically within a few hours. The goal is to break up the clot, restore blood flow to the affected part of the brain, and limit the damage.
- By restoring blood flow, ACTILYSE 20MG INJECTION significantly improves the chances of reducing long-term disability associated with a stroke. Acting fast is crucial; the earlier it is given, the more brain tissue can be saved. Patients treated with this medication often have a better chance of recovering more function compared to those who don't receive it, provided it's administered appropriately within the critical time window.
- While highly effective, ACTILYSE 20MG INJECTION is a potent medication and carries risks. The most serious side effect is bleeding, which can occur in the brain or elsewhere in the body, such as the stomach or intestines. Because it dissolves clots, it affects the body's natural ability to stop bleeding. This is why careful patient selection and monitoring are essential.
- Doctors must carefully evaluate a patient before giving ACTILYSE 20MG INJECTION. It is not suitable for everyone. You should not receive this medicine if you have an allergy to Alteplase or its ingredients. It is also avoided in patients with recent significant trauma, especially head injuries, or those who have recently undergone major surgery, due to a high risk of severe bleeding. Conditions like severe high blood pressure that is not controlled, active internal bleeding, or certain blood clotting disorders also prevent its use.
- Furthermore, the body processes this medication using the liver and kidneys. Therefore, caution is needed for patients with severe problems in these organs as it might affect how the drug is cleared. Older age, particularly over 75 years, is another factor doctors consider, as it can increase the likelihood of bleeding complications. A thorough medical history and several tests are performed to ensure the benefits outweigh the risks for each individual patient. Close monitoring of vital signs and neurological status is standard practice during and after administration.
Uses of ACTILYSE 20MG INJECTION
- Treatment for heart attack
- Acute ischemic stroke
- Acute massive pulmonary embolism (life-threatening blood clots in lungs)
Side Effects of ACTILYSE 20MG INJECTION
Like all medications, ACTILYSE 20MG INJECTION can cause some side effects, although not everyone will experience them.
Safety Advice for ACTILYSE 20MG INJECTION
Pregnancy
Consult a DoctorIf a pregnant woman requires treatment with ACTILYSE 20MG INJECTION, then they should consult a healthcare provider. They will weigh the potential benefits of resolving the critical situation against the potential risks to the developing fetus.
Dosage of ACTILYSE 20MG INJECTION
- ACTILYSE 20MG INJECTION is a powerful medication that is always given directly into a vein, which is called intravenous administration. This procedure is *only* performed by a qualified healthcare professional, like a doctor or a nurse, in a hospital or clinic setting. It's crucial that you do not attempt to administer this medication yourself. The exact amount of ACTILYSE 20MG INJECTION you receive (the dosage) and how it is given will be carefully decided by your doctor. They will consider your specific medical condition, your overall health, weight, and how you respond to treatment. This personalised approach ensures the medication is used safely and effectively for you. You will be closely monitored during and after the injection to check for any effects or side effects. If you have any questions about why you are receiving this injection or how it works, please talk to your healthcare provider.
How to store ACTILYSE 20MG INJECTION?
- Keep ACTILYSE 20MG INJ away from the reach of children and pets.
- Store ACTILYSE 20MG INJ at room temperature.
Benefits of ACTILYSE 20MG INJECTION
- ACTILYSE 20MG INJECTION is a powerful medication primarily used to treat serious conditions caused by blood clots, most notably acute ischemic stroke. It functions as a powerful clot-dissolver. The way it works is by activating a natural process within the body. Specifically, it converts a substance called plasminogen into another enzyme known as plasmin. Plasmin is the body's key tool for breaking down fibrin, which is the protein that forms the structural mesh of blood clots. By breaking down fibrin, ACTILYSE effectively dissolves the clot. In the context of an acute ischemic stroke, where a clot blocks blood flow to a part of the brain, dissolving the clot quickly is critical. This restoration of blood flow helps to limit the amount of damage to brain tissue caused by lack of oxygen and nutrients. Administered urgently in a hospital setting, ACTILYSE aims to reopen blocked blood vessels, thereby minimizing potential long-term disability and improving patient outcomes. Its ability to rapidly restore circulation makes it a vital treatment in emergency situations involving harmful blood clots.
How to use ACTILYSE 20MG INJECTION
- ACTILYSE 20MG INJECTION is a powerful medication that is always administered directly into a vein. This process is known as intravenous administration and is strictly carried out by trained healthcare professionals, such as doctors or nurses, in a hospital or clinical setting. It is crucial that this injection is given under close medical supervision because it is a potent therapy requiring careful monitoring. The exact amount of ACTILYSE 20MG INJECTION you receive, how quickly it is given, and the duration of the treatment will be precisely determined by your doctor. They will take into account your specific medical condition, your overall health status, weight, and how you respond to treatment. You should never attempt to self-administer this medication. Relying on the expertise of your healthcare team ensures the injection is given safely and effectively, maximizing its benefits while minimizing potential risks. Follow all instructions provided by the medical staff throughout the administration process.
FAQs
Is ACTILYSE 20MG INJECTION effective in all cases of stroke or blood clots?
ACTILYSE 20MG INJECTION is most effective when administered within the recommended time window and in specific cases of acute ischemic stroke, pulmonary embolism, or acute myocardial infarction. Its use must be carefully evaluated on a case-by-case basis by qualified healthcare professionals.
Are there any contraindications for using ACTILYSE 20MG INJECTION?
ACTILYSE 20MG INJECTION is contraindicated in certain conditions, such as active bleeding, recent major surgery, intracranial hemorrhage, known hypersensitivity to it, and other situations with an increased risk of bleeding.
Are there any specific tests required before administering ACTILYSE 20MG INJECTION?
Before administering ACTILYSE 20MG INJECTION, healthcare professionals typically perform brain imaging (CT or MRI) to rule out hemorrhagic stroke, which is a contraindication for this medication use. They may also conduct blood tests to assess coagulation parameters and ensure that the patient meets the necessary criteria for treatment.
Is there a reversal agent for ACTILYSE 20MG INJECTION if bleeding occurs?
There is no specific reversal agent for ACTILYSE 20MG INJECTION. In case of severe bleeding complications, healthcare professionals may use supportive measures, blood products, or other interventions to manage bleeding. Close monitoring and immediate medical attention are essential to address any adverse events promptly.
Can ACTILYSE 20MG INJECTION be used in children or adolescents?
ACTILYSE 20MG INJECTION is not approved for use in children or adolescents for stroke treatment. Its use in this population is limited to specific cases and requires expert evaluation and consideration of the risks and benefits.
Does ACTILYSE 20MG INJECTION interact with other medicines?
It's important to inform your doctor about all medications you are currently taking, including prescription and over-the-counter drugs, as ACTILYSE 20MG INJECTION can interact with certain substances, particularly those affecting blood clotting. Your healthcare professional will assess potential interactions.
What important advice or precautions should I know about ACTILYSE 20MG INJECTION?
Always consult a healthcare professional before starting or making any changes to your medication regimen. Inform your doctor about conditions like bleeding disorders, recent surgery or trauma, gastrointestinal bleeding, or other conditions that may increase bleeding risk. Close monitoring of patients is required throughout treatment to detect any bleeding or adverse reactions promptly. It should be used in a hospital setting with access to emergency facilities, and immediate medical care must be available in case of complications. Pregnancy and breastfeeding women should consult a doctor before starting treatment. Advanced age can increase the risk of bleeding complications with this medication, particularly in patients over 75. Dosage adjustment may be required in elderly patients.
What is the main active ingredient in ACTILYSE 20MG INJECTION?
The main active ingredient in ACTILYSE 20MG INJECTION is ALTEPLASE.
Is ACTILYSE 20MG INJECTION used to treat heart disorders?
ACTILYSE 20MG INJECTION is prescribed for certain conditions including specific heart disorders like acute myocardial infarction (heart attack) and pulmonary embolism (blood clot in the lungs).
References
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BOEHRINGER INGELHEIM INDIA PVT LTD
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India
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