AJADUO 10/5MG TABLET 10'S

How AJADUO 10/5MG TABLET 10'S Works

• AJADUO 10/5MG TABLET 10'S is a combination medication containing two active ingredients: Amlodipine and Olmesartan Medoxomil. These components work synergistically to effectively lower blood pressure in individuals with hypertension (high blood pressure). Understanding how each ingredient functions is crucial to appreciating the overall mechanism of action of AJADUO.
• Amlodipine belongs to a class of drugs known as calcium channel blockers (CCBs). Calcium plays a vital role in muscle contraction, including the muscles in the walls of blood vessels. Amlodipine works by blocking calcium from entering these muscle cells. This blockage causes the blood vessels to relax and widen, a process known as vasodilation. As the blood vessels dilate, the resistance to blood flow decreases, leading to a reduction in blood pressure. Amlodipine primarily affects the arteries and arterioles, the smaller branches of arteries.
• Olmesartan Medoxomil, on the other hand, is an angiotensin II receptor blocker (ARB). Angiotensin II is a hormone in the body that causes blood vessels to constrict, which raises blood pressure. It also stimulates the release of aldosterone, a hormone that causes the kidneys to retain sodium and water, further contributing to increased blood volume and blood pressure. Olmesartan Medoxomil blocks the action of angiotensin II by preventing it from binding to its receptors in various tissues, including the blood vessels and adrenal glands. By blocking angiotensin II, Olmesartan Medoxomil causes vasodilation and reduces the release of aldosterone, leading to decreased sodium and water retention, and ultimately lowering blood pressure.
• The combined effect of Amlodipine and Olmesartan Medoxomil provides a complementary and enhanced antihypertensive effect. Amlodipine reduces blood pressure by dilating blood vessels, while Olmesartan Medoxomil prevents blood vessel constriction and reduces fluid retention. This dual mechanism helps to achieve better blood pressure control compared to using either medication alone. By targeting different pathways involved in blood pressure regulation, AJADUO 10/5MG TABLET 10'S offers a comprehensive approach to managing hypertension.
• In summary, AJADUO 10/5MG TABLET 10'S works by Amlodipine blocking calcium entry into blood vessel muscle cells, causing relaxation and vasodilation, and Olmesartan Medoxomil blocking Angiotensin II, preventing vasoconstriction and reducing sodium and water retention. This combination effectively lowers blood pressure in hypertensive patients.

Possible side effects of AJADUO 10/5MG TABLET may include: * **Common:** * Nausea * Diarrhea * Headache * Dizziness * Edema (swelling of ankles and feet) * Fatigue * Muscle cramps * Abdominal pain * Indigestion * Skin rash * Increased thirst * **Uncommon:** * Vomiting * Constipation * Dry mouth * Weakness * Blurred vision * Increased sweating * Changes in taste * Hair loss * Joint pain * Back pain * Nasal congestion * Cough * Urinary frequency * Palpitations * Orthostatic hypotension (drop in blood pressure upon standing) * Erectile dysfunction * Gynecomastia (enlargement of breasts in men) * Mood changes, including anxiety and depression * **Rare:** * Pancreatitis * Hepatitis * Jaundice * Severe allergic reactions (rash, itching, swelling, difficulty breathing) * Stevens-Johnson syndrome * Toxic epidermal necrolysis * Angioedema * Heart failure (worsening of existing condition) This is not an exhaustive list. If you experience any unusual symptoms while taking AJADUO 10/5MG TABLET, consult your doctor immediately.

• If you miss a dose of AJADUO 10/5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep AJADUO 10/5MG TAB 1X10 away from the reach of children and pets.
• Store AJADUO 10/5MG TAB 1X10 at room temperature.

• Take AJADUO 10/5MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or discontinue the medication without consulting your healthcare provider. Consistent adherence to the prescribed regimen is crucial for optimal blood sugar control and preventing potential complications associated with diabetes. Missing doses can lead to fluctuations in blood sugar levels, impacting overall health.
• AJADUO 10/5MG TABLET 10'S is typically taken once daily, preferably with your first main meal. Taking it with food helps to reduce the likelihood of stomach upset and enhances the absorption of the medication. Consistent timing of the dose each day also aids in maintaining stable blood sugar levels throughout the day. This is especially important to regulate post-meal glucose spikes effectively.
• Monitor your blood sugar levels regularly, as advised by your doctor. Keeping a log of your blood sugar readings can help you and your healthcare provider assess how well the medication is working and make any necessary adjustments to your treatment plan. Regular monitoring also helps you understand how your body responds to different foods, activities, and stressors, enabling you to make informed lifestyle choices.
• Follow a healthy diet and exercise regularly while taking AJADUO 10/5MG TABLET 10'S. This medication works best when combined with lifestyle modifications. Focus on consuming balanced meals with controlled carbohydrate intake, and engage in at least 30 minutes of moderate-intensity exercise most days of the week. Consult a registered dietitian or certified diabetes educator for personalized guidance on diet and exercise plans tailored to your specific needs.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, dizziness, and confusion. Always carry a source of fast-acting sugar, like glucose tablets or juice, to quickly raise your blood sugar levels if needed. If you experience frequent or severe episodes of hypoglycemia, inform your doctor, as your medication dosage may need adjustment. Understanding and managing hypoglycemia is a vital part of diabetes management.

• AJADUO 10/5MG TABLET 10'S can be taken with or without food. However, it is recommended to take it at the same time each day to maintain consistent blood levels of the medication.
• Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medication, as it may increase the levels of tadalafil in your blood, potentially leading to increased side effects.