AKILOS TH 4MG TABLET 10'S

How AKILOS TH 4MG TABLET 10'S Works

• AKILOS TH 4MG TABLET 10'S is a combination medication designed to alleviate pain and inflammation associated with musculoskeletal conditions. It combines the potent anti-inflammatory and analgesic properties of thiocolchicoside and etoricoxib to provide comprehensive relief.
• Thiocolchicoside, a muscle relaxant, works primarily by acting on GABA receptors in the central nervous system. GABA (gamma-aminobutyric acid) is a neurotransmitter that inhibits nerve impulses. By enhancing GABAergic neurotransmission, thiocolchicoside helps to reduce muscle spasms and stiffness. Specifically, it binds to GABA-A receptors, increasing their affinity for GABA, and also activates glycine receptors, further contributing to its muscle-relaxing effects. This dual action helps to break the cycle of pain and muscle spasm commonly seen in conditions like lower back pain, neck pain, and other musculoskeletal disorders. The reduction in muscle tone not only alleviates pain but also improves mobility and range of motion.
• Etoricoxib, on the other hand, is a selective cyclooxygenase-2 (COX-2) inhibitor. COX-2 is an enzyme responsible for the production of prostaglandins, which are key mediators of inflammation, pain, and fever. Unlike traditional nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit both COX-1 and COX-2 enzymes, etoricoxib selectively targets COX-2. This selectivity is crucial because COX-1 is involved in maintaining the protective lining of the stomach and is essential for platelet function. By selectively inhibiting COX-2, etoricoxib effectively reduces the production of prostaglandins at the site of inflammation without significantly affecting the COX-1 mediated processes, thereby lowering the risk of gastrointestinal side effects such as ulcers and bleeding commonly associated with non-selective NSAIDs.
• The synergistic action of thiocolchicoside and etoricoxib in AKILOS TH 4MG TABLET 10'S provides a multi-faceted approach to managing pain and inflammation. Thiocolchicoside addresses the muscle spasm component, while etoricoxib tackles the inflammatory and pain pathways. This combination allows for effective pain relief, reduced muscle stiffness, and improved overall function in individuals suffering from acute musculoskeletal conditions. Furthermore, the COX-2 selectivity of etoricoxib enhances the tolerability of the medication, making it a suitable option for individuals who may be at higher risk of gastrointestinal complications with traditional NSAIDs. Patients should always follow their healthcare provider's instructions regarding dosage and duration of treatment to maximize benefits and minimize potential side effects.
• In summary, AKILOS TH 4MG TABLET 10'S works by combining a centrally acting muscle relaxant (thiocolchicoside) with a selective COX-2 inhibitor (etoricoxib). This dual mechanism of action effectively addresses both muscle spasms and inflammation, providing comprehensive relief for musculoskeletal pain while minimizing the risk of gastrointestinal side effects.

Common side effects of AKILOS TH 4MG TABLET may include nausea, vomiting, stomach pain, diarrhea, loss of appetite, heartburn, constipation, drowsiness, dizziness, headache, blurred vision, dry mouth, increased sweating, weakness, fatigue, skin rash, itching, and swelling. Less common but potentially serious side effects include allergic reactions (hives, difficulty breathing, swelling of the face, lips, tongue, or throat), liver problems (yellowing of the skin or eyes, dark urine, pale stools), kidney problems (decreased urination, swelling of ankles or feet), gastrointestinal bleeding (bloody or black stools, vomiting blood), heart problems (chest pain, irregular heartbeat), mental/mood changes (confusion, depression, hallucinations), seizures, and Stevens-Johnson syndrome (severe skin rash with blistering). Consult your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of Akilos TH 4mg Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep AKILOS TH 4MG TAB 1X10 away from the reach of children and pets.
• Store AKILOS TH 4MG TAB 1X10 at room temperature.

• Take AKILOS TH 4MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. This ensures optimal therapeutic benefit and minimizes potential side effects. Consistency is key for effective relief from pain and muscle stiffness.
• AKILOS TH contains a combination of thiocolchicoside and a pain reliever. Be aware of potential side effects such as drowsiness, dizziness, or stomach upset. Avoid activities requiring alertness, like driving, until you know how the medicine affects you. If side effects persist or worsen, inform your doctor promptly.
• Inform your doctor about all other medications, herbal supplements, and vitamins you are currently taking before starting AKILOS TH. This is crucial to prevent potential drug interactions that could reduce the efficacy of AKILOS TH or increase the risk of adverse effects. Pay special attention to blood thinners, antidepressants and muscle relaxants.
• Store AKILOS TH 4MG TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage ensures the medication remains effective and prevents accidental ingestion. Do not store in the bathroom.
• If you miss a dose of AKILOS TH, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Doubling the dose can increase the risk of side effects.

• AKILOS TH 4MG TABLET 10'S is generally safe to take with or without food. However, it is advisable to take it at a fixed time each day to maintain consistent levels of the medicine in your body. If you experience any stomach upset, taking it with food may help reduce this.