AKLIEF CREAM 30 GM

How AKLIEF CREAM 30 GM Works

• AKLIEF CREAM 30 GM contains trifarotene, a retinoid that selectively targets retinoic acid receptor gamma (RARγ), the most common retinoid receptor found in the skin. This unique selectivity allows AKLIEF to address the specific pathways involved in acne development with potentially fewer side effects compared to non-selective retinoids.
• At the cellular level, trifarotene works through several mechanisms to combat acne. Firstly, it normalizes follicular keratinization, preventing the buildup of dead skin cells that can clog pores and lead to the formation of comedones (blackheads and whiteheads). By promoting proper shedding of skin cells, AKLIEF helps keep pores clear and reduces the likelihood of new acne lesions.
• Secondly, trifarotene possesses anti-inflammatory properties. It modulates the inflammatory response in the skin, reducing redness, swelling, and pain associated with acne lesions. By targeting inflammation, AKLIEF can help to calm existing breakouts and prevent the formation of new inflammatory lesions, such as papules and pustules.
• Furthermore, trifarotene may also affect sebum production. Sebum, an oily substance produced by the sebaceous glands, can contribute to acne development when produced in excess. While the exact mechanism is still being researched, trifarotene may help to regulate sebum production, reducing the oily environment that promotes acne formation. By targeting these key factors in acne pathogenesis – abnormal keratinization, inflammation, and potentially sebum production – AKLIEF CREAM 30 GM effectively reduces the number of acne lesions and improves overall skin clarity. Its targeted action on RARγ aims to deliver potent acne treatment while minimizing skin irritation, leading to better patient compliance and outcomes.
• In summary, AKLIEF CREAM 30 GM works by: Normalizing skin cell turnover to prevent clogged pores; Reducing inflammation to alleviate redness and swelling; and potentially Regulating sebum production to create a less favorable environment for acne. This multi-pronged approach makes it an effective treatment for acne vulgaris.

Like all medicines, Aklief Cream can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Dry skin * Application site exfoliation * Acne (pimples) * Application site itching * Application site pain/stinging sensation **Uncommon side effects (may affect up to 1 in 100 people):** * Application site dermatitis * Application site eczema * Application site burn * Application site redness (erythema) * Application site discoloration If you experience severe irritation, stop using Aklief Cream until the irritation subsides. If irritation persists, consult your doctor.

• If you forget to apply AKLIEF Cream at your regular time, apply it as soon as you remember. However, if it is almost time for your next application, skip the missed application and apply the cream at the next scheduled time. Do not apply a double dose to make up for a missed one.

• Keep AKLIEF CREAM 30GM away from the reach of children and pets.
• Store AKLIEF CREAM 30GM at room temperature.

• Start Slowly: When you first begin using Aklief Cream, apply it sparingly. A pea-sized amount is usually sufficient for the entire face. This helps your skin adjust to the medication and minimizes potential irritation.
• Nighttime Application is Key: Aklief Cream is designed for nighttime use. Apply it to clean, dry skin before you go to bed. Avoid applying other topical products at the same time, unless directed by your dermatologist, to prevent interactions.
• Moisturize Regularly: Aklief Cream can sometimes cause dryness or peeling. To combat this, use a gentle, non-comedogenic moisturizer both morning and night. Hydrated skin is healthier and better able to tolerate the medication.
• Sun Protection is Essential: Aklief Cream can make your skin more sensitive to the sun. Apply a broad-spectrum sunscreen with an SPF of 30 or higher every morning, even on cloudy days. Reapply throughout the day, especially if you're spending time outdoors. Wear protective clothing, like hats and sunglasses, for added protection.
• Be Patient and Consistent: It may take several weeks or even months to see significant improvement in your acne with Aklief Cream. Consistency is crucial. Continue using the medication as directed by your dermatologist, even if you don't see immediate results. Don't get discouraged, and don't stop using the cream without consulting your doctor.
• Avoid Sensitive Areas: Be careful to avoid applying Aklief Cream to sensitive areas such as the eyes, lips, and nostrils. If accidental contact occurs, rinse thoroughly with water.
• Communicate with Your Dermatologist: Keep your dermatologist informed about your progress and any side effects you experience. They can adjust your treatment plan as needed to ensure the best possible outcome.

• AKLIEF Cream 30 GM is for external use only and is unlikely to be affected by food. However, it is always a good practice to inform your doctor about your diet and any supplements you are taking.