ALBUREL 25% INJECTION 50 ML

How ALBUREL 25% INJECTION 50 ML Works

• ALBUREL 25% Injection is a sterile solution made from human albumin, a natural protein found in blood plasma. Its primary function is to increase the blood volume and maintain adequate oncotic pressure, which is crucial for fluid balance within the body. Here’s a detailed look at how it works:
• **1. Restoring Blood Volume:** When there's a significant loss of blood volume due to trauma, surgery, or severe bleeding, ALBUREL 25% Injection rapidly expands the circulatory volume. The albumin molecules draw fluid from the interstitial spaces (the spaces between cells) into the bloodstream. This immediate increase in blood volume helps stabilize blood pressure and improves the delivery of oxygen and nutrients to vital organs.
• **2. Maintaining Oncotic Pressure:** Albumin is a major contributor to oncotic pressure, also known as colloid osmotic pressure. This pressure prevents fluid from leaking out of blood vessels into surrounding tissues. Conditions like severe burns, liver disease, or kidney disorders can lead to low albumin levels (hypoalbuminemia), reducing oncotic pressure and causing fluid accumulation in tissues (edema). ALBUREL 25% Injection replenishes albumin levels, restoring oncotic pressure, and drawing excess fluid back into the bloodstream, thereby reducing edema.
• **3. Binding and Transporting Substances:** Albumin acts as a carrier protein, binding to and transporting various substances throughout the body, including hormones, enzymes, drugs, and toxins. By maintaining adequate albumin levels, ALBUREL 25% Injection supports the efficient transport of these essential compounds, ensuring they reach their target sites and functions optimally. This is particularly important in conditions where the body's ability to transport these substances is compromised.
• **4. Supporting Microcirculation:** By improving blood volume and oncotic pressure, ALBUREL 25% Injection also enhances microcirculation – the flow of blood through the tiniest blood vessels. This ensures that tissues receive adequate oxygen and nutrients, which is vital for tissue repair and overall health. Improved microcirculation is particularly beneficial in critically ill patients who may have impaired blood flow to vital organs.
• In essence, ALBUREL 25% Injection works by boosting blood volume, maintaining fluid balance through oncotic pressure, facilitating the transport of essential substances, and improving microcirculation. This multifaceted action makes it a valuable treatment in a range of medical conditions, helping to stabilize patients and support their recovery.

Possible side effects of ALBUREL 25% Injection may include: * **Common:** Fever, chills, nausea, vomiting, headache, flushing, urticaria (hives), rash. * **Less Common:** Changes in blood pressure (hypotension or hypertension), rapid heart rate (tachycardia), difficulty breathing (dyspnea), fluid overload (pulmonary edema), allergic reactions (anaphylaxis). * **Rare:** Severe allergic reactions, kidney problems. **Important Considerations:** * This is not an exhaustive list. Other side effects may occur. * Inform your doctor immediately if you experience any unusual symptoms after receiving ALBUREL 25% Injection. * The frequency and severity of side effects can vary from person to person. * Patients with pre-existing heart or kidney conditions may be at higher risk for certain side effects.

• Since ALBUREL 25% INJECTION 50 ML is usually administered by a healthcare professional in a hospital or clinical setting, the chances of missing a dose are minimal. However, if you have concerns about a missed dose, please consult your doctor or the healthcare provider administering the medication for further guidance.

• Keep ALBUREL 25% INJ 50ML away from the reach of children and pets.
• Store ALBUREL 25% INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

• **Understand the Purpose:** ALBUREL 25% Injection is primarily used to restore blood volume in conditions like shock, surgery, or severe burns. It helps maintain fluid balance in your body. Always consult your doctor to understand if it is the right choice for your specific condition and what are other options available.
• **Dosage and Administration:** This medication is administered intravenously (IV) by a healthcare professional. The dosage is carefully calculated based on your individual needs, weight, medical condition, and response to treatment. Never attempt to self-administer this medication. Ensure that you understand the reasons behind the specific dosage prescribed for you.
• **Monitor for Allergic Reactions:** Although rare, allergic reactions to ALBUREL are possible. Watch out for symptoms such as rash, itching, swelling, dizziness, or difficulty breathing. If you experience any of these, inform your healthcare provider immediately. Pre-existing allergies should be discussed with your doctor before starting treatment.
• **Inform Your Doctor About Other Medications:** Before receiving ALBUREL, tell your doctor about all other medications you are taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements. Some medications can interact with ALBUREL, affecting how it works or increasing the risk of side effects. Special attention should be given to diuretics, ACE inhibitors and ARBs
• **Stay Hydrated:** While ALBUREL helps maintain fluid balance, staying adequately hydrated is crucial, especially if you are receiving it for conditions like dehydration or burns. Follow your doctor's instructions regarding fluid intake. Dehydration and overhydration both are harmful so follow your doctor's instructions carefully.
• **Storage and Handling:** ALBUREL 25% Injection should be stored according to the manufacturer's instructions, typically in a refrigerator. It should be protected from light and freezing. Once opened, any unused portion should be discarded promptly. The solution should be clear and colorless to slightly yellow. Do not use if it is cloudy or contains particles. These guidelines are primarily for healthcare professionals.
• **Be Aware of Potential Side Effects:** Common side effects of ALBUREL may include mild fever, chills, or nausea. Serious side effects are rare but can include fluid overload, pulmonary edema, or heart failure. Report any unusual symptoms to your healthcare provider promptly. Discuss potential side effects with your doctor to know what to watch for.
• **Conditions to Discuss with Your Doctor:** Before receiving ALBUREL, inform your doctor if you have any pre-existing medical conditions, especially heart failure, kidney disease, or bleeding disorders. These conditions can affect how your body responds to the medication. Also, provide a comprehensive medical history to your healthcare provider.
• **Regular Monitoring:** While on ALBUREL, your healthcare provider will regularly monitor your vital signs, fluid balance, and electrolyte levels. This helps ensure that the medication is working effectively and to detect any potential problems early on.
• **Pregnancy and Breastfeeding:** If you are pregnant or breastfeeding, discuss the risks and benefits of ALBUREL with your doctor before receiving it. It is important to weigh the potential benefits against any potential risks to the fetus or infant.

• There are no known interactions between ALBUREL 25% Injection and food. It is administered intravenously, so its absorption and effectiveness are not affected by what you eat or drink.