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Content Reviewed By:
Dr. Manoj Shah
, (MBBS)
Written By:
Ms. Priyanka Shah
, (B.Pharm)
Common side effects of ALPRAX PLUS NRX TABLET may include: Drowsiness, Lightheadedness, Dizziness, Headache, Fatigue, Muscle weakness, Problems with coordination, Slurred speech, Memory problems, Confusion, Irritability, Anxiety, Depression, Blurred vision, Dry mouth, Constipation, Nausea, Changes in appetite, Weight changes, Difficulty urinating, Decreased sexual interest. Less common but more serious side effects include: Allergic reactions (rash, itching, swelling), Breathing difficulties, Seizures, Jaundice (yellowing of skin or eyes), Suicidal thoughts or behavior, Aggression, Hallucinations, Unusual changes in mood or behavior.

Other Medical Conditions and Interactions
Use under medical supervisionNRX tablets should be used with particular caution in individuals with a history of substance use disorder, respiratory disease, seizure disorders, bipolar disorder, or suicidal ideation.
Alprax Plus NRX Tablet 10'S is a medicine used to treat anxiety and panic disorders.
The main ingredients in Alprax Plus NRX Tablet 10'S are Alprazolam and Nortriptyline.
Alprax Plus NRX Tablet 10'S is used to treat anxiety, panic disorders, and depression.
Common side effects of Alprax Plus NRX Tablet 10'S include drowsiness, dizziness, dry mouth, and constipation.
Alprax Plus NRX Tablet 10'S can be habit-forming, so it should only be taken as prescribed by a doctor.
Alprax Plus NRX Tablet 10'S should be stored at room temperature, away from direct sunlight and moisture.
Drinking alcohol with Alprax Plus NRX Tablet 10'S can increase side effects like drowsiness and dizziness, so it should be avoided.
If you miss a dose of Alprax Plus NRX Tablet 10'S, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
Symptoms of an overdose of Alprax Plus NRX Tablet 10'S include confusion, loss of coordination, slow reflexes, drowsiness, and loss of consciousness.
Alprax Plus NRX Tablet 10'S is not recommended for use during pregnancy as it may harm the fetus.
Breastfeeding women should consult a doctor before using Alprax Plus NRX Tablet 10'S, as it may pass into breast milk and affect the baby.
Alprax Plus NRX Tablet 10'S is not recommended for use in children unless specifically directed by a doctor.
Alprax Plus NRX Tablet 10'S can interact with certain other medications, so it's important to tell your doctor about all the medications you are taking.
Some other brands of Alprazolam include Xanax, Alprax, and Tranquil.
It takes about 1-2 hours for Alprax Plus NRX Tablet 10'S to start working.
In many settings, an NRX tablet refers to a prescription-only psychotropic medicine that contains a combination of alprazolam (a benzodiazepine) and sertraline (an SSRI antidepressant). It is typically prescribed for anxiety disorders, depressive episodes associated with anxiety, and related mood or stress conditions, under the supervision of a qualified healthcare professional.
The alprazolam component enhances the effect of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, leading to reduced anxiety and sedation. The sertraline component selectively inhibits serotonin reuptake in the brain, which helps improve mood and reduce anxiety over time. Together, they provide both short-term anxiolytic and longer-term antidepressant effects.
You should take an NRX tablet exactly as prescribed by your doctor, usually by swallowing it whole with water, with or without food. Do not crush, chew, or break sustained-release or modified-release formulations unless your doctor or pharmacist specifically instructs you to do so. Never change the dose or frequency on your own.
No. Abruptly stopping NRX tablets, especially after prolonged use, can lead to withdrawal symptoms such as rebound anxiety, insomnia, irritability, tremor, or flu-like symptoms. Any change in dose or discontinuation should be done gradually according to a tapering plan provided by your doctor.
Common side effects may include drowsiness, dizziness, fatigue, headache, nausea, diarrhea or constipation, dry mouth, changes in appetite, sleep disturbances, and sexual dysfunction. These effects are often mild to moderate and may lessen as your body adjusts, but you should inform your doctor if they are persistent or troublesome.
The alprazolam component can cause tolerance, dependence, and withdrawal if used for long periods, at high doses, or in individuals with a history of substance use disorder. NRX tablets should be used only as prescribed, for the shortest duration necessary, and under close medical supervision to minimize the risk of dependence and misuse.
Alcohol should be avoided while taking NRX tablets. Both alcohol and alprazolam depress the central nervous system and can lead to excessive drowsiness, impaired coordination, slowed breathing, and increased risk of accidents. Alcohol may also worsen mood symptoms and interfere with the antidepressant effect of sertraline.
If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist for advice.
NRX tablets may not be suitable for individuals with a history of hypersensitivity to alprazolam, sertraline, or other benzodiazepines or SSRIs; those with severe liver impairment; uncontrolled narrow-angle glaucoma; certain serious psychiatric conditions without close specialist supervision; or those taking specific interacting medicines such as monoamine oxidase inhibitors (MAOIs). Your doctor will assess your overall health and medication profile before prescribing.
Use during pregnancy or breastfeeding requires careful risk–benefit assessment by a specialist. Both alprazolam and sertraline can cross the placenta and are excreted in breast milk. Potential risks to the fetus or infant, including withdrawal or adaptation symptoms, must be weighed against the clinical need for treatment. Do not start or stop NRX tablets in pregnancy or while breastfeeding without medical advice.
The anxiolytic effect of alprazolam may be noticed within hours to days, while the full antidepressant and anti-anxiety effects of sertraline typically develop over several weeks. Your doctor may review your response after a few weeks and adjust treatment as needed. Do not discontinue the medicine prematurely without consulting your prescriber.
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TORRENT PHARMACEUTICALS LIMITED
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