AMFOSTED 500 INJECTION
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AMFOSTED 500 INJECTION
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AMFOSTED 500 INJECTION

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AMFOSTED 500 INJECTION

By THERDOSE PHARMA PVT LTD

MRP

4545

₹1818

60 % OFF

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Product DetailsArrow

About AMFOSTED 500 INJECTION

  • AMFOSTED 500 INJECTION contains the active ingredient Amifostine, belonging to a class of medications known as chemoprotective agents. This medication is primarily used to protect the kidneys from the potential harmful side effects of the chemotherapy drug cisplatin, particularly in patients undergoing treatment for ovarian cancer. Additionally, it helps alleviate dry mouth, a common side effect experienced by patients undergoing radiation therapy following head and neck cancer surgery. AMFOSTED 500 INJECTION works by providing a protective barrier against the damaging effects of both chemotherapy drugs and radiation treatment on healthy tissues.
  • Before starting treatment with AMFOSTED 500 INJECTION, it's important to inform your healthcare provider about your complete medical history, especially if you have a history of low blood pressure, stroke, seizures, or any other medical conditions. This will help your doctor assess the risks and benefits of using this medication for you. Open communication ensures the safest and most effective treatment plan.
  • You should not use AMFOSTED 500 INJECTION if you have a known allergy to Amifostine or any of the other inactive ingredients in the injection. If you experience any allergic reactions, such as a red, itchy rash or hives, after receiving the injection, notify your physician immediately. This medication is also not recommended for use during pregnancy or if you are planning to become pregnant, as it may pose risks to the developing fetus. Furthermore, inform your doctor if you have any pre-existing conditions, such as liver disease, kidney disease, heart disorders, heart failure, or heart rhythm changes, as these conditions may affect how the medication is administered and monitored.
  • The most common side effects associated with AMFOSTED 500 INJECTION include reduced blood pressure, nausea, and vomiting. These side effects are generally manageable, and your healthcare team will provide you with strategies to minimize their impact. It's important to be aware that this medication may also impair fertility in both men and women. If you are planning to have children in the future, discuss your options with your doctor before starting treatment.

Uses of AMFOSTED 500 INJECTION

  • Safeguarding the kidneys from the detrimental effects of chemotherapy medications, ensuring optimal kidney function during cancer treatment with AMFOSTED 500 INJECTION.
  • Alleviating dryness in the mouth following head and neck cancer treatment, promoting patient comfort and aiding in swallowing and speech affected by AMFOSTED 500 INJECTION.

Side Effects of AMFOSTED 500 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Skin rash
  • Nausea
  • Vomiting
  • Decreased blood pressure
  • Severe skin rash
  • Severe hypersensitivity reaction

Safety Advice for AMFOSTED 500 INJECTIONArrow

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Pregnancy

UNSAFE

Do not take AMFOSTED 500 INJECTION if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment.

Dosage of AMFOSTED 500 INJECTIONArrow

  • AMFOSTED 500 INJECTION will be administered by a qualified healthcare professional, such as a doctor or nurse, in a hospital or clinical setting equipped for cancer chemotherapy. The dosage, method of administration (intravenous), and duration of treatment will be determined by your doctor. They will carefully consider your specific medical condition, its severity, your overall health, body weight, any other existing medical conditions, and your age to personalize the treatment plan for optimal results. This medication is always administered intravenously, directly into a vein. It is crucial not to attempt to self-administer this injection, as it requires specialized knowledge and training to ensure safe and effective delivery. The healthcare professional will monitor you closely during the infusion to manage any potential side effects and ensure the medication is working as expected.
  • Your doctor will explain the details of your treatment schedule. If you have any questions about the dosage, route of administration, or the therapy duration, you should ask your doctor.

How to store AMFOSTED 500 INJECTION?Arrow

  • Keep AMFOSTED 500MG INJ away from the reach of children and pets.
  • Store AMFOSTED 500MG INJ at room temperature.

Benefits of AMFOSTED 500 INJECTIONArrow

  • The active metabolite within AMFOSTED 500 INJECTION is crucial for its protective effects against cellular damage and radiation. Once administered, this metabolite is efficiently absorbed by cells, allowing it to effectively neutralize harmful substances. It achieves this by binding to and detoxifying reactive platinum compounds and alkylating agents, which are common byproducts of chemotherapy. Furthermore, it acts as a scavenger of free radicals, unstable molecules that can cause oxidative stress and damage to cellular components.
  • Beyond direct detoxification, the metabolite in AMFOSTED 500 INJECTION exerts its protective effects through various mechanisms. It inhibits cell death pathways, preventing the premature destruction of healthy cells exposed to cytotoxic treatments. It also influences gene expression, potentially upregulating genes involved in cellular repair and defense, and downregulating those that promote cell damage. Additionally, it modulates enzyme activity, further contributing to the overall cytoprotective and radioprotective actions of the medication. These combined effects help to mitigate the adverse effects of cancer treatments and protect healthy tissues from damage.

How to use AMFOSTED 500 INJECTIONArrow

  • AMFOSTED 500 INJECTION will be administered by a doctor or other qualified healthcare professional in a hospital or clinical setting experienced in cancer chemotherapy. The administration will be intravenous, meaning it will be given directly into your vein. It is crucial that you do not attempt to self-administer this injection.
  • The precise dosage, the method of administration, and the length of your treatment will be carefully determined by your doctor. They will consider several factors, including the specifics of your condition, its severity, your overall health, including weight, any other existing medical conditions, and your age. Your doctor will tailor the treatment plan to best suit your individual needs and ensure the most effective and safe outcome.
  • It is essential to follow your doctor’s instructions precisely regarding the treatment schedule and any other recommendations they provide. If you have any questions or concerns about your treatment, don't hesitate to discuss them with your doctor or healthcare team. They are there to provide support and guidance throughout your therapy.

FAQs

Can a patient with kidney problems take AMFOSTED 500 INJECTION?Arrow

AMFOSTED 500 INJECTION is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of this injection may not be needed in kidney disease patients. Please consult your doctor for more advice.

Is hypotension a side effect of AMFOSTED 500 INJECTION?Arrow

Low blood pressure (hypotension) may occur with AMFOSTED 500 INJECTION. Report to your doctor immediately if you have any symptoms of blurred vision, confusion, severe dizziness, faintness, lightheadedness, sweating, or unusual tiredness or weakness.

What if I overdose or take two doses of AMFOSTED 500 INJECTION?Arrow

If you unknowingly overdosed or took two doses of AMFOSTED 500 INJECTION, immediately inform your healthcare professional and seek medical advice.

What if I miss a dose of AMFOSTED 500 INJECTION?Arrow

Do not miss your dose. Keep all your appointments with the dosing regularly. In case if you forget or missed an appointment, inform your healthcare professional and reschedule the dosing.

Are there any special dietary instructions I should follow while taking AMFOSTED 500 INJECTION?Arrow

Unless your doctor tells you to avoid certain foods, continue your normal diet. Consult your doctor for more advice on dietary restrictions.

Does AMFOSTED 500 INJECTION interact with other drugs?Arrow

NULL interaction of AMFOSTED 500 INJECTION with other drungs

What advice should I follow while taking AMFOSTED 500 INJECTION?Arrow

Drink extra fluids during the 24 hours before you receive this medicine. You may be advised to take calcium supplements and other medications to help prevent nausea and vomiting. Do not smoke or consume alcohol while using this medicine. Your doctor may advise you to take certain blood tests during the treatment to monitor any unwanted side effects.

What is AMFOSTED 500 INJECTION made of?Arrow

AMFOSTED 500 INJECTION is made of AMIFOSTINE.

For what conditions is AMFOSTED 500 INJECTION prescribed?Arrow

AMFOSTED 500 INJECTION is prescribed for Oncology.

References

Book Icon

Cumberland Pharmaceuticals Inc, US Food and Drug Administration

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Book Icon

Kouvaris JR, Kouloulias VE, Vlahos LJ. Amifostine: The First Selective-Target and Broad-Spectrum Radioprotector. The Oncologist [Internet]. 2007 Jun 1;12(6):738–47. Available from

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Marketer / Manufacturer Details

THERDOSE PHARMA PVT LTD

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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