AMLOVAS M 5/25MG TABLET 10'S

How AMLOVAS M 5/25MG TABLET 10'S Works

• AMLOVAS M 5/25MG TABLET 10'S is a combination medication designed to effectively manage hypertension (high blood pressure) by utilizing the synergistic effects of two active ingredients: Amlodipine and Metoprolol. Understanding how each component works individually and together provides valuable insight into the drug's overall mechanism of action.
• Amlodipine belongs to a class of drugs called calcium channel blockers (CCBs). Calcium plays a crucial role in muscle contraction, including the muscles in the heart and blood vessel walls. Amlodipine selectively blocks calcium from entering these muscle cells. By reducing the influx of calcium, Amlodipine causes the smooth muscles in the blood vessel walls to relax. This relaxation leads to vasodilation, which means the blood vessels widen. As the blood vessels dilate, the resistance to blood flow decreases, resulting in a lowering of blood pressure. Amlodipine primarily targets the peripheral blood vessels, which contributes to its effectiveness in reducing systolic and diastolic blood pressure.
• Metoprolol, on the other hand, is a beta-blocker. It selectively blocks beta-1 adrenergic receptors, which are predominantly found in the heart. By blocking these receptors, Metoprolol reduces the effects of adrenaline (epinephrine) and noradrenaline (norepinephrine) on the heart. This results in several beneficial effects for individuals with hypertension. First, Metoprolol slows down the heart rate, giving the heart more time to fill with blood between beats. Second, it decreases the force with which the heart contracts, reducing the amount of blood pumped out with each beat (cardiac output). Finally, Metoprolol also reduces the release of renin, an enzyme produced by the kidneys that contributes to the elevation of blood pressure. By reducing renin levels, Metoprolol further aids in lowering blood pressure.
• The combination of Amlodipine and Metoprolol in AMLOVAS M 5/25MG TABLET 10'S provides a comprehensive approach to blood pressure management. Amlodipine's vasodilation effect complements Metoprolol's ability to reduce heart rate and cardiac output. This dual mechanism of action allows for more effective blood pressure control than either drug could achieve alone. This synergistic effect makes AMLOVAS M 5/25MG TABLET 10'S a valuable option for individuals whose hypertension is not adequately controlled with a single medication.
• In essence, AMLOVAS M 5/25MG TABLET 10'S works by relaxing blood vessels (Amlodipine) and reducing the heart's workload (Metoprolol), leading to a significant reduction in blood pressure and improved cardiovascular health.

Common side effects of AMLOVAS M 5/25MG TABLET may include: Headache, dizziness, sleepiness, fatigue, palpitations, flushing (sense of warmth in the face, ears, neck and trunk), ankle swelling, abdominal pain, nausea, edema (swelling), constipation, diarrhea, indigestion, shortness of breath, visual disturbance, muscle cramps, increased liver enzymes, changes in heart rhythm, cough, increased potassium level in blood, glucose intolerance, decreased white blood cell count, decreased blood platelets, mood changes, sleep disturbances, tremor, visual disturbance, vertigo, ringing in ears, low blood pressure, inflammation of nose, difficulty in urination, increased frequency of urination, impotence, breast enlargement in male, hair loss. Less common or rare side effects may include: Allergic reaction, anxiety, chest pain, fainting, dry mouth, increased sweating, skin rash, itching, weight gain, weight loss, exacerbation of psoriasis, peripheral neuropathy, vomiting, taste disturbance, jaundice, hepatitis, pancreatitis, gingival hyperplasia, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, photosensitivity, angioedema.

• If you miss a dose of AMLOVAS M 5/25MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep AMLOVAS M 5/25MG TAB 1X10 away from the reach of children and pets.
• Store AMLOVAS M 5/25MG TAB 1X10 at room temperature.

• **Take AMLOVAS M 5/25MG TABLET 10'S Regularly:** Consistency is key! Take this medication at the same time each day to maintain a steady level in your body and maximize its effectiveness in controlling blood pressure. Missing doses can lead to fluctuations in your blood pressure.
• **Monitor Your Blood Pressure:** Keep a log of your blood pressure readings at home and share it with your doctor. This helps them understand how well the medication is working and adjust your dosage if needed. Regular monitoring also empowers you to be proactive about your health.
• **Be Mindful of Dietary Sodium:** Reduce your salt intake while taking AMLOVAS M 5/25MG TABLET 10'S. High sodium levels can counteract the effects of the medication and worsen hypertension. Avoid processed foods, canned soups, and excessive table salt.
• **Stay Hydrated:** Drink plenty of water throughout the day. Adequate hydration supports healthy blood volume and circulation, complementing the effects of the medication. Aim for at least 8 glasses of water daily, unless your doctor advises otherwise.
• **Consult Your Doctor Before Taking Other Medications:** Inform your doctor about all other medications, supplements, and herbal remedies you are taking. Some substances can interact with AMLOVAS M 5/25MG TABLET 10'S, potentially affecting its efficacy or causing adverse effects. This includes over-the-counter medications and even certain herbal products. Also, Limit alcohol consumption as it might interfere with AMLOVAS M 5/25MG TABLET 10'S.

• AMLOVAS M 5/25MG TABLET 10'S may be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood levels.
• Avoid consuming grapefruit or grapefruit juice while taking this medication, as it may increase the levels of amlodipine in your blood, potentially leading to increased side effects.