AMPHO-B 50MG INJECTION
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AMPHO-B 50MG INJECTION
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AMPHO-B 50MG INJECTION

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AMPHO-B 50MG INJECTION

By VHB LIFE SCIENCES LIMITED

MRP

296

₹251.6

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Product DetailsArrow

About AMPHO-B 50MG INJECTION

  • AMPHO-B 50MG INJECTION is an antifungal medication that contains Amphotericin B as its active ingredient. It is primarily used to combat serious fungal infections affecting one or more internal organs. This injection is also indicated for patients experiencing a high fever and neutropenia (a condition characterized by a reduced count of white blood cells), where a fungal infection is suspected. Furthermore, it serves as a treatment for visceral leishmaniasis, a parasitic disease affecting specific populations. This medication works by binding to ergosterol, a component of fungal cell membranes, thereby disrupting the integrity of the membrane and leading to the death of the fungal cell.
  • Before you receive AMPHO-B 50MG INJECTION, it's important to inform your healthcare provider about any allergies you may have, particularly to Amphotericin B or any other components of the injection. Exercise caution and discuss with your physician if you have a history of severe allergic reactions, kidney or liver issues, or if you are currently undergoing dialysis. Also, inform your doctor if you have low potassium levels, as this injection can further affect potassium balance. Be vigilant for potential infusion reactions during administration, which can manifest as flushing, itching, nausea, swelling of the face, mouth, tongue, or airways, and difficulty breathing. Seek immediate medical attention if you experience any of these symptoms.
  • Prior to commencing the full course of treatment, your physician may administer a small test dose of AMPHO-B 50MG INJECTION to assess for any allergic responses. It is essential to disclose if you have diabetes, as each vial of this medication contains sugar. If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your physician before starting treatment. The dosage and duration of treatment with this drug will be determined by your doctor based on the specific nature and severity of your condition. It is crucial to adhere strictly to your doctor's instructions regarding dosage and administration to ensure the effectiveness of the treatment and minimize potential side effects.
  • To maximize the effectiveness of AMPHO-B 50MG INJECTION and minimize potential complications, it's important to maintain open communication with your healthcare provider. Report any unusual symptoms or side effects promptly. Regular monitoring of kidney function and electrolyte levels may be necessary during treatment. Following a healthy lifestyle, including a balanced diet and adequate hydration, can also contribute to your overall well-being and support your body's response to the medication. It is also advised to avoid any other medications or supplements that have not been explicitly approved by your doctor. This will help to avoid the risk of drug interactions.

Uses of AMPHO-B 50MG INJECTION

  • Treatment of fungal infections. This includes addressing a range of fungal infections affecting different parts of the body, such as skin infections, nail infections, and systemic infections. Medications work to eradicate the fungal organisms, alleviating symptoms and promoting healing.

Side Effects of AMPHO-B 50MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. Serious side effects include allergic reactions (itching, rash, hives, shortness of breath, wheezing), increased blood sugar, decreased potassium, shortness of breath and fever, chills, or shivering. Common side effects include headache, dizziness, diarrhea, nausea, indigestion, and abdominal pain.

  • Serious allergic reactions (sudden onset of itching, rash or hives on the skin, shortness of breath and wheezing)
  • Increased blood sugar levels
  • Decreased potassium levels
  • Shortness of breath
  • Fever, chills, or shivering
  • Headache
  • Dizziness
  • Diarrhea
  • Nausea
  • Indigestion
  • Abdominal Pain

Safety Advice for AMPHO-B 50MG INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

If you are pregnant, suspecting, or planning for the pregnancy, consult your physician for more advice before taking AMPHO-B 50MG INJECTION. Physicians may prescribe this medicine only when it is needed.

Dosage of AMPHO-B 50MG INJECTIONArrow

  • AMPHO-B 50MG INJECTION is administered by a healthcare professional, such as a doctor or nurse, in a hospital or clinic environment. It is delivered intravenously, meaning it's given through a drip directly into your vein. It is crucial to understand that you should never attempt to self-administer this injection. The dosage and the length of your treatment will be determined by your doctor, who will consider several factors.
  • These factors include the severity of your condition, your body weight, and other individual health considerations. The doctor will carefully assess your response to the medication to adjust the dosage as needed throughout your treatment course. It is essential to adhere to the prescribed dosage and schedule provided by your healthcare provider for optimal results.
  • If you have any concerns or questions about the dosage or administration of AMPHO-B 50MG INJECTION, please consult your doctor or nurse for clarification. They can provide personalized guidance and address any uncertainties you may have. Always follow their instructions precisely for the safe and effective use of this medication.

How to store AMPHO-B 50MG INJECTION?Arrow

  • Keep AMPHO-B 50MG INJ away from the reach of children and pets.
  • Store AMPHO-B 50MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of AMPHO-B 50MG INJECTIONArrow

  • AMPHO-B 50MG INJECTION is a potent antifungal medication that combats fungal infections by targeting the cell membranes of susceptible fungi. Its primary mechanism involves binding to ergosterol, a crucial component of fungal cell membranes. This binding action disrupts the integrity of the membrane, leading to alterations in its permeability. Consequently, essential intracellular components leak out of the fungal cells, ultimately causing cell death. The effectiveness of AMPHO-B 50MG INJECTION stems from its ability to selectively target fungal cells while minimizing harm to human cells, which have different membrane compositions. This targeted action makes it a valuable tool in treating serious systemic fungal infections. It is often used when other antifungal treatments have proven ineffective, showcasing its importance in combating resistant fungal strains. Its use should be carefully monitored by healthcare professionals due to potential side effects.
  • This disruption leads to a cascade of events that destabilize the fungal cell. The compromised membrane allows for the uncontrolled passage of ions and other molecules, disrupting the delicate balance necessary for cell survival. The loss of essential nutrients and the influx of toxic substances contribute to the overall demise of the fungal cell.
  • AMPHO-B 50MG INJECTION's targeted approach minimizes damage to healthy human cells, making it a valuable treatment option for severe fungal infections.

How to use AMPHO-B 50MG INJECTIONArrow

  • AMPHO-B 50MG INJECTION is administered by a healthcare professional, such as a doctor or nurse, in a hospital or clinic environment. This medication is given intravenously, meaning it's delivered directly into your vein through an infusion drip. It is crucial that you do not attempt to self-administer this injection.
  • The dosage and the length of your treatment will be determined by your doctor. Several factors influence this decision, including the severity of your infection, your body weight, kidney function and your overall health condition. It's important to follow your doctor's instructions precisely regarding the dosage and duration of the treatment. This will ensure that the medication is most effective in combating the infection while minimizing the risk of potential side effects. Do not change or skip your dose.
  • During the infusion, the healthcare provider will monitor you closely for any adverse reactions. Be sure to inform them immediately if you experience any discomfort, pain, swelling at the injection site, fever, chills, difficulty breathing, or any other unusual symptoms. Regular blood tests may be conducted to monitor kidney function and ensure that the medication is working effectively.

FAQs

What are the possible side effects of AMPHO-B 50MG INJECTION?Arrow

While AMPHO-B 50MG 50mg Injection is generally well-tolerated, it can still have side effects. Common side effects may include fever, chills, headache, nausea, vomiting, increased blood sugar levels, muscle or joint pain, and infusion-related reactions. In rare cases, it may cause more serious side effects such as cardiac arrest, kidney damage or allergic reactions.

Can AMPHO-B 50MG 50mg Injection be used in pediatric patients?Arrow

AMPHO-B 50MG Injection can be used in babies more than 1 years old, but the dosage and administration may vary depending on the child's age, weight, and specific medical condition. It is crucial to follow the healthcare provider's instructions and closely monitor the child's response to treatment.

Why is AMPHO-B 50MG 50mg Injection less toxic?Arrow

AMPHO-B 50MG 50mg Injection is less toxic because it is less nephrotoxic. Low toxicity of this medicine may be due to the small number of binding receptors in the drug.

What are the advantages of using AMPHO-B 50MG Injection over other antifungal medications?Arrow

One of the key advantages of AMPHO-B 50MG Injection is its lower toxicity compared to conventional drugs. This makes it a preferred choice, especially for patients more susceptible to antifungal medications' side effects. Additionally, this drug has a prolonged circulation time in the body, allowing for less frequent dosing.

Can I discontinue taking AMPHO-B 50MG Injection once I feel better?Arrow

Even if you feel better, do not discontinue taking AMPHO-B 50MG Injection without consulting your doctor. Before the illness is treated, your symptoms may improve. As a result, it is recommended that you continue your treatment for the suggested term for better and more complete treatment.

NULL interaction of AMPHO-B 50MG INJECTION with other drungsArrow

No information is available regarding this.

Advice related to AMPHO-B 50MG INJECTION?Arrow

AMPHO-B 50MG Injection may cause damage to the kidney. Inform your doctor if you have kidney problems. It may be necessary to continue this medication for several weeks to several months to treat certain infections. Stopping the medication too early may result in a return of the infection. Tell your doctor if your condition lasts or gets worse.

What molecule/combination is used for making AMPHO-B 50MG INJECTION?Arrow

AMPHOTERICIN B is molecule/combination used for making AMPHO-B 50MG INJECTION.

For what ailments/diseases/conditions is AMPHO-B 50MG INJECTION prescribed?Arrow

AMPHO-B 50MG INJECTION is prescribed for various fungal infections.

How does AMPHO-B 50MG INJECTION work?Arrow

AMPHO-B 50MG INJECTION works by destroying fungal cells.

References

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Gilead Sciences International Ltd, Electronic medicines compendium (EMC)

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Gilead Sciences, Inc, US Food and Drug Administration

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Lifecare innovations

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Falah Hasan et al; Topical Amphomul 50mg Injection formulas: Promising new application; [Published on August 2019]

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Marketer / Manufacturer Details

VHB LIFE SCIENCES LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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