AMPILOX CAPSULE 10'S

How AMPILOX CAPSULE 10'S Works

• AMPILOX CAPSULE 10'S is a combination medication containing ampicillin and cloxacillin, two antibiotics that belong to the penicillin family. It is primarily used to treat bacterial infections by targeting the bacteria's ability to form cell walls. Understanding how AMPILOX works involves looking at the mechanisms of its individual components.
• **Ampicillin's Mechanism:** Ampicillin is a broad-spectrum antibiotic, meaning it is effective against a wide range of bacteria. It functions by inhibiting the synthesis of peptidoglycans, which are essential components of bacterial cell walls. Specifically, ampicillin binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall. These PBPs are enzymes responsible for cross-linking peptidoglycans, providing the cell wall with its structural integrity. By binding to PBPs, ampicillin prevents the cross-linking process, weakening the cell wall. As a result, the bacterial cell becomes fragile and prone to lysis (rupture), leading to its death.
• **Cloxacillin's Role:** Cloxacillin is a penicillinase-resistant penicillin. Penicillinase, also known as beta-lactamase, is an enzyme produced by some bacteria that can inactivate penicillin antibiotics by breaking the beta-lactam ring, a crucial structural component of these drugs. Cloxacillin's unique structure makes it resistant to degradation by penicillinase. This means it can still effectively inhibit bacterial cell wall synthesis even in the presence of penicillinase-producing bacteria. By combining ampicillin with cloxacillin, AMPILOX offers a broader spectrum of activity and overcomes resistance mechanisms that some bacteria employ.
• **Synergistic Action:** The combination of ampicillin and cloxacillin in AMPILOX creates a synergistic effect. Ampicillin targets a broad range of bacteria, while cloxacillin protects the ampicillin from being broken down by bacterial enzymes. This synergistic action enhances the overall effectiveness of the antibiotic, allowing it to combat a wider range of infections, especially those caused by bacteria that have developed resistance to other penicillin antibiotics.
• **Overall Impact:** When you take AMPILOX CAPSULE 10'S, the ampicillin and cloxacillin are absorbed into the bloodstream and distributed throughout the body. They then target bacteria at the site of infection, inhibiting cell wall synthesis and ultimately leading to bacterial cell death. This helps to reduce the bacterial load, alleviate symptoms, and resolve the infection. It is crucial to complete the full course of AMPILOX as prescribed by your doctor, even if you start feeling better, to ensure that all the bacteria are eradicated and to prevent the development of antibiotic resistance.

Like all medicines, AMPILOX CAPSULE 10'S can cause side effects, although not everybody gets them. Common side effects (may affect up to 1 in 10 people): * Diarrhea * Nausea * Vomiting * Skin rash * Hives Uncommon side effects (may affect up to 1 in 100 people): * Fungal infections (such as oral thrush or vaginal yeast infection) * Abdominal pain Rare side effects (may affect up to 1 in 1,000 people): * Allergic reactions, including swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, wheezing, and collapse. * Inflammation of the liver (hepatitis) * Jaundice (yellowing of the skin or eyes) * Stevens-Johnson syndrome (a severe skin reaction with blistering and peeling of the skin) * Toxic epidermal necrolysis (a more severe form of Stevens-Johnson syndrome) * Blood disorders, including a decrease in white blood cells (leukopenia), red blood cells (anemia), and platelets (thrombocytopenia) * Kidney inflammation (nephritis) Very rare side effects (may affect up to 1 in 10,000 people): * Black hairy tongue * Antibiotic-associated colitis (inflammation of the colon caused by antibiotics)

• If you miss a dose of AMPILOX CAPSULE, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep AMPILOX CAP 1X10 away from the reach of children and pets.
• Store AMPILOX CAP 1X10 at room temperature.

• Complete the Full Course: Even if you start feeling better, finish the entire course of Ampilox Capsule 10'S as prescribed by your doctor. Stopping early can lead to the infection returning and becoming more resistant to antibiotics.
• Take it as Prescribed: Follow your doctor's instructions carefully regarding the dosage and timing of Ampilox Capsule 10'S. Do not take more or less than prescribed, and maintain consistent intervals between doses to ensure a steady level of medication in your system.
• Stay Hydrated: Drink plenty of water while taking Ampilox Capsule 10'S. This helps flush out the infection and reduces the risk of side effects like nausea or stomach upset. Aim for at least 8 glasses of water a day.
• Inform Your Doctor of Other Medications: Before starting Ampilox Capsule 10'S, inform your doctor about all other medications, supplements, and herbal remedies you are taking. Some medications can interact with Ampilox, potentially reducing its effectiveness or increasing the risk of side effects.
• Report Any Side Effects: If you experience any unusual or bothersome side effects while taking Ampilox Capsule 10'S, such as rash, itching, swelling, severe diarrhea, or difficulty breathing, contact your doctor immediately. These could be signs of an allergic reaction or other serious complication.

• It is recommended to take AMPILOX CAP 10'S on an empty stomach, at least 30 minutes before or 2 hours after meals, as food can interfere with its absorption. However, if you experience stomach upset, you can take it with a light snack.