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Content Reviewed By:
Dr. Manoj Shah
, (MBBS)
Written By:
Ms. Priyanka Shah
, (B.Pharm)
Most side effects are temporary and resolve as your body adapts to the medication. If these effects continue or cause concern, please seek medical advice.

General cardiovascular precautions
Specialist supervision advisedAngiplat 2.5 should be used under the supervision of a physician experienced in managing coronary artery disease and other cardiovascular conditions. Baseline assessment typically includes blood pressure, heart rate, electrocardiogram, and evaluation of concomitant therapies.
No, you should not take sildenafil if you are taking ANGIPLAT 2.5MG TABLET 25'S. Taking these two medicines together can cause an excessive fall in blood pressure, which may even be life-threatening.
ANGIPLAT 2.5MG TABLET 25'S decreases the blood pressure by relaxing the blood vessels but is not recommended for the treatment of high blood pressure. The drop in blood pressure may cause lightheadedness, especially when changing your position suddenly.
Yes, excessive use of ANGIPLAT 2.5MG TABLET 25'S may cause tolerance, which means that ANGIPLAT 2.5MG TABLET 25'S may lose its effectiveness on you. Therefore, usually the doctors prescribe the smallest dose required for effective relief of acute angina attack. This helps maintain the effectiveness of ANGIPLAT 2.5MG TABLET 25'S.
Excess ANGIPLAT 2.5MG TABLET 25'S may result in low blood pressure, sweating, nausea, vomiting, headache, weak and fast pulse. It may also cause weakness, lightheadedness on standing and the patient might even faint. The patient will require emergency medical treatment in such a case.
Stopping ANGIPLAT 2.5MG TABLET 25'S suddenly may bring on attacks of angina, especially if you have been using it for several weeks or more. Talk to your doctor who will advise you to reduce the dose gradually over 4 to 6 weeks before you stop using it completely.
ANGIPLAT 2.5MG TABLET 25'S is prescribed to prevent attacks of heart-related chest pain (angina) in patients with coronary artery disease. In this disease, the blood vessels (coronary arteries) which supply blood to the heart become narrowed because of which the heart has to work harder to get enough oxygen. ANGIPLAT 2.5MG TABLET 25'S prevents angina by relaxing the blood vessels so that the heart does not have to work very hard. Also, relaxation of coronary arteries increases the oxygen supply to the heart.
Angiplat 2.5 is a sustained‑release oral tablet used in the management and prevention of angina pectoris (chest pain due to reduced blood flow to the heart). Its active ingredient is nitroglycerin (glyceryl trinitrate), an organic nitrate that relaxes and widens blood vessels, thereby reducing the workload on the heart and improving blood flow to the heart muscle.
Angiplat 2.5 contains nitroglycerin, which is converted in the body to nitric oxide, a potent vasodilator. Nitric oxide relaxes the smooth muscle in blood vessel walls, leading to dilation of veins and arteries. Venous dilation reduces the amount of blood returning to the heart (preload), and arterial dilation lowers systemic vascular resistance (afterload). Together, these effects decrease the heart’s oxygen demand and improve oxygen supply to the myocardium, helping to prevent angina episodes.
Angiplat 2.5 is a sustained‑release formulation and is generally not intended for the rapid relief of an acute angina attack. It is used for long‑term prophylaxis to reduce the frequency and severity of angina episodes. For sudden chest pain, fast‑acting nitroglycerin preparations, such as sublingual tablets or sprays, are usually recommended. Patients should follow the emergency plan provided by their cardiologist for acute chest pain and seek urgent medical attention if pain is severe, prolonged, or atypical.
You should not stop taking Angiplat 2.5 on your own, even if your chest pain appears to be controlled. Abrupt discontinuation of long‑term nitrate therapy can lead to a rebound increase in angina frequency or severity. Any change in therapy, including dose reduction or discontinuation, should be done only under the guidance of your treating physician, who will assess your cardiovascular status and may adjust other medicines accordingly.
Common side effects associated with Angiplat 2.5 include headache, flushing, dizziness, light‑headedness, a feeling of warmth, and sometimes nausea. These effects are usually related to blood vessel dilation and may lessen as your body adapts to the medicine. Some people may experience low blood pressure, especially when standing up quickly, which can cause faintness or, rarely, fainting. If side effects are severe, persistent, or worrying, you should contact your healthcare provider promptly.
Angiplat 2.5 should generally be avoided in individuals with severe hypotension, shock, marked anaemia, increased intracranial pressure, or known hypersensitivity to nitroglycerin or other nitrates. It is also contraindicated in patients taking phosphodiesterase‑5 inhibitors (such as sildenafil, tadalafil, or vardenafil) or soluble guanylate cyclase stimulators (such as riociguat), due to the risk of profound hypotension. Patients with hypertrophic obstructive cardiomyopathy, severe aortic or mitral valve stenosis, or constrictive pericarditis require careful specialist evaluation before nitrate therapy.
No. Angiplat 2.5 must not be taken together with phosphodiesterase‑5 inhibitors used for erectile dysfunction or pulmonary hypertension, such as sildenafil, tadalafil, or vardenafil. The combination can cause a marked and potentially life‑threatening drop in blood pressure, leading to dizziness, fainting, myocardial infarction, or stroke. You should inform your doctor if you are using or planning to use any of these medicines so that a safe treatment plan can be arranged.
If you feel dizzy or light‑headed after taking Angiplat 2.5, you should sit or lie down immediately to reduce the risk of falling. Avoid sudden changes in posture, such as standing up quickly. Do not drive or operate machinery while you feel unwell. If dizziness is severe, associated with chest pain, shortness of breath, or fainting, or if it persists despite rest, seek medical attention promptly and inform your doctor at the next visit so that your treatment can be reassessed.
Use of Angiplat 2.5 during pregnancy or breastfeeding requires careful individual assessment by a physician. Human data on nitroglycerin use in pregnancy and lactation are limited. The medicine should be prescribed only if the expected benefit to the mother outweighs any potential risk to the fetus or breastfed infant. Pregnant or breastfeeding women should not start or continue Angiplat 2.5 without explicit medical advice, and any symptoms such as dizziness, low blood pressure, or reduced fetal movements should be reported promptly.
Alcohol can enhance the blood pressure‑lowering effect of Angiplat 2.5 and increase the likelihood of dizziness, faintness, or fainting, so alcohol consumption is generally discouraged while on this medicine. Angiplat 2.5 may also interact with other antihypertensives, diuretics, and vasodilators, potentially leading to additive hypotensive effects. It is important to inform your doctor about all medicines you are taking, including beta‑blockers, calcium channel blockers, ACE inhibitors, angiotensin receptor blockers, and any over‑the‑counter products, so that potential interactions can be evaluated and your regimen adjusted if needed.
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MICRO LABS LIMITED
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