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APREZO 10MG TABLET 4'S
By GLENMARK PHARMACEUTICALS LIMITED
MRP
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Tablet
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Product Details
About APREZO 10MG TABLET 4'S
- APREZO 10MG TABLET 4'S is primarily used for the treatment of certain inflammatory conditions, specifically psoriasis and psoriatic arthritis. Here is an overview of Apremilast:
- APREZO 10MG TABLET 4'S works by inhibiting the enzyme phosphodiesterase-4 (PDE4). This helps to modulate the overactive immune response associated with psoriasis and psoriatic arthritis. APREZO 10MG TABLET 4'S is approved for the treatment of moderate to severe plaque psoriasis in adult patients who are candidates for systemic therapy. It is also indicated for the treatment of active psoriatic arthritis in adult patients, either as monotherapy or in combination with other disease-modifying antirheumatic drugs (DMARDs).
- APREZO 10MG TABLET 4'S has been shown to significantly improve the signs and symptoms of plaque psoriasis, including reducing the redness, scaling, and thickness of skin lesions. It can lead to a reduction in psoriasis severity and improve the quality of life for patients with this chronic skin condition.
Uses of APREZO 10MG TABLET 4'S
- Effectively treats moderate to severe plaque psoriasis, reducing the redness, scaling, and thickness of skin lesions.
- Improves the signs and symptoms of psoriatic arthritis, including joint pain, swelling, and tenderness.
- Can be used for psoriatic arthritis treatment.
- Helps improve physical function and inhibit the progression of structural damage associated with psoriatic arthritis.
How APREZO 10MG TABLET 4'S Works
- APREZO 10MG TABLET 4'S works by targeting a specific enzyme called phosphodiesterase-4 (PDE4), which is found in various cells of the body, including immune cells. Here is an explanation of how APREZO 10MG TABLET 4'S works:
- Inhibition of PDE4: APREZO 10MG TABLET 4'S acts as a selective inhibitor of PDE4. By inhibiting PDE4, it prevents the breakdown of cyclic adenosine monophosphate (cAMP), an important signaling molecule within cells.
- Modulation of Inflammatory Response: By inhibiting PDE4 and increasing cAMP levels, APREZO 10MG TABLET 4'S helps regulate the immune system and modulate the inflammatory response. It reduces the production of certain pro-inflammatory cytokines (chemical messengers) such as tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-17 (IL-17), and interleukin-23 (IL-23).
- Anti-Inflammatory Effects: APREZO 10MG TABLET 4'S ability to inhibit the production of pro-inflammatory cytokines helps to reduce the overall inflammation in the body. This can be beneficial in conditions such as psoriasis and psoriatic arthritis, where excessive inflammation plays a role in the development of symptoms.
- Impact on Immune Cells: APREZO 10MG TABLET 4'S affects various immune cells, including T cells, B cells, and dendritic cells. By modulating the activity of these immune cells, it helps to regulate the immune response and reduce inflammation.
Side Effects of APREZO 10MG TABLET 4'S
- Diarrhea
- Nausea
- Headache
- Upper respiratory tract infections
- Decreased appetite
- Fatigue
- Weight loss
- Depression or worsening of pre-existing depression
- Suicidal thoughts or behavior (rare but serious)
Dosage of APREZO 10MG TABLET 4'S
- Adults:
- For the treatment of moderate to severe plaque psoriasis: The typical starting dosage is 30 mg taken orally twice daily for the first 5 days, followed by a maintenance dosage of 30 mg taken orally twice daily thereafter.
- For the treatment of active psoriatic arthritis: The recommended dosage is 30 mg taken orally twice daily.
- Pediatrics (17 years and younger):
- APREZO 10MG TABLET 4'S is generally not recommended for use in pediatric patients. Safety and efficacy in this age group have not been well-established.
- Elderly:
- The dosage of APREZO 10MG TABLET 4'S for elderly patients (65 years and older) is typically the same as that for adults. However, individualized dosage adjustments may be necessary based on the patient's overall health, renal function, and other factors. It is important to consult with a healthcare professional for appropriate dosage recommendations.
How to store APREZO 10MG TABLET 4'S?
- Store Apremilast at room temperature, typically between 20°C to 25°C (68°F to 77°F).
- Keep the medication in its original container or packaging to protect it from light.
- Store it in a dry place, away from areas with high humidity, such as bathrooms.
FAQs
What is APREZO 10MG TABLET 4'S?
APREZO 10MG TABLET 4'S is an oral medication used for the treatment of certain inflammatory conditions, such as psoriasis and psoriatic arthritis.
What conditions is APREZO 10MG TABLET 4'S used to treat?
APREZO 10MG TABLET 4'S is used to treat moderate to severe plaque psoriasis and active psoriatic arthritis in adult patients.
How is APREZO 10MG TABLET 4'S administered?
APREZO 10MG TABLET 4'S is administered orally as a tablet, usually taken twice daily or as prescribed by a healthcare professional.
Are there any specific precautions or warnings associated with APREZO 10MG TABLET 4'S?
Precautions and warnings associated with APREZO 10MG TABLET 4'S include the risk of depression, suicidal thoughts, and possible drug interactions. It is important to discuss these factors with a healthcare professional.
Can APREZO 10MG TABLET 4'S be used during pregnancy or while breastfeeding?
The use of APREZO 10MG TABLET 4'S during pregnancy or breastfeeding should be discussed with a healthcare professional, considering the potential risks and benefits.
Are there any known drug interactions with APREZO 10MG TABLET 4'S?
APREZO 10MG TABLET 4'S may interact with certain medications, so it is important to inform healthcare professionals about all medications being taken.
How long does it take for APREZO 10MG TABLET 4'S to start working?
The onset of action for APREZO 10MG TABLET 4'S may vary among individuals and the specific condition being treated. It is best to consult a healthcare professional for an estimation of the expected time frame.
What should I do if I miss a dose of APREZO 10MG TABLET 4'S?
If a dose of APREZO 10MG TABLET 4'S is missed, it should be taken as soon as remembered, unless it is close to the time for the next scheduled dose.
References
Ratings & Review
Great experience👍🏻
PRASHANT KATARIYA
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Reviewed on 29-01-2024
(5/5)
Generic medicines available at low cost
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Reviewed on 09-07-2023
(5/5)
Good
Dhara Patva
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Reviewed on 10-02-2024
(5/5)
Very very very excellent services and ease of getting medicines with great discounts. I recommend users to go for Medikart for all medicines. Thank you
Deepa Sippy
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Reviewed on 11-03-2024
(5/5)
Good place with excellent service and good customer service
Kunal Patel
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Reviewed on 13-05-2023
(5/5)
Marketer / Manufacturer Details
GLENMARK PHARMACEUTICALS LIMITED
Country of Origin -
India
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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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